Objective To evaluate the cost-effectiveness and -benefit of the World Bank Loan Project on Schistosomiasis Control in Qianjiang City. Methods According to the national scheme the cost-effectiveness and cost-benefit of the project were analysed. Results After the project was carried out for 9 years, poputation schistosome infections rate decreased by 56.48%; cattle infections rate decreased by 48.08%; snail areas reduced 1224 hm 2(42.76%). Infected snail areas reduced 273 hm 2(17.13%). Snail infections rate decreased by 97.04%. The investment for infections rate decreased by 1% in 100 people was 1384.47 yuan. The investment for infections rate decreased by 1% in 100 head of cattle was 3386.96 yuan. The investment to reduce 1 hm 2 snail ares was 8935.63 yuan. Conclusion For one yuan investment, the benefit was 7.96 yuan and the total of the net benefit was 106784700 yuan in 9 years.