1.Characteristic analysis for informed choice of dental patients
Yongwu WANG ; Feng JIANG ; Xiong ZHANG
Chinese Journal of Hospital Administration 2009;25(4):258-260
Objective Probing into the "informed choice" and its features for patients in dentist clinics for the purposes of optimizing clinical practice and reducing doctor-patient disputes, for a better patient satisfaction.Methods Questionnaire are designed for a random sampling among 106 outpatients in the dentist clinic, studying the conflict, support factors and information channels of informed choices available for dentistry patients.Results The 100 questionnaires recovered indicate that patients at large are faced with conflicts in informed choice, and they tend to seek doctor's advice for comparison among different treatments.Conclusion Dental patients deserve "informed choice", as this may guide clinical practices and improve patient satisfaction, for a more harmonious doctor-patient relationship.
2.Analysis of professor ZHANG Lei's cleaning turbidity therapy
Feng JIANG ; Rongxin ZHANG ; Yuxin SUN
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(01):-
Professor ZHANG Lei is one of the most renowned doctors in traditional Chinese medicine. He is good at treating miscellaneous disease of internal medicine, and summarizes eight clinical therapy from long-term clinical practice, and cleaning turbidity therapy is one of the most characteristic therapy. Cleaning turbidity therapy is founded under today's improvement of living standards and changes of lifestyle where more and more turbidity syndromes are caused. Qianjin Weijing Decoction is used as main prescription and modified according to different zang-fu where turbidity syndromes are located. On account of cleaning turbidity therapy is one of the eliminating pathogens therapy, strengthening healthy qi must be used according to power of healthy qi, especially healthy qi of spleen and stomach.
3.Biomechanical study and application of lateral-anterior internal fixation with TSRH in thoracolumbar fracture
Zhenhua JIANG ; Xiangdong CHEN ; Feng ZHANG
Orthopedic Journal of China 2006;0(06):-
0.05).[Conclusion]Lateral-anterior fixation with use TSRH not only has effective result in strength, rigidity and stability of the spine, but also is superior to the control group in loading-bearing ability and stability of the spine. There is no significant difference between the TSRH group and Z-plate group. But TSRH is relatively simple to operate and is cheaper than Z-plate, and has exact clinical ontcome.
4.Clinical study on the effects of Buyang-Huanwu decoction combined with western medicine on early renal injury of patients with type 2 diabetes
Ke JIANG ; Runzhou ZHANG ; Wei FENG
International Journal of Traditional Chinese Medicine 2012;34(8):683-685
Objective To investigate the effects of Buyang-Huanwu decoction combined with western medicine on early diabetic renal injury.Methods 200 cases of early diabetic renal injury were randomly recruited into study group and control group,with 100 cases in each group.The control group was treated with insulin injection and oral benazepril hydrochloride,and the blood pressure,blood lipid changes were closely monitored; while the study group was additionally treated with Buyang-Huanwu decoction on the basis of the control group.Results The total therapeutic effects in the study group was significantly higher than the control group (x2=15.62,P<0.01).The values of FBG,2 h PG,DBP,SBP,HbAlc in both groups were significantly reduced after the treatment (P<0.05,t=4.23,4.47,3.59,3.87,3.99 in the study group,t=4.34,4.76,4.05,3.78,3.69 in the control group) ; but the difference between the two groups had no significance (P>0.05).Before treatment rnALB,Urea,Cr,TG and TC were not significantly different (P>0.05) ; the values of mALB,Ureaand Cr were significantly reduced in the study group after the treatment (P<0.05,t=4.56,3.73,3.28);especially mALB in the study group was obviously lower than the control group (P<0.05,t=5.01).Conclusion Buyang-Huanwu decoction combined with western medicine was effective to treat early renal damage of type 2 diabetes,with the functions of reducing urinary protein,improving microcirculation and protecting renal function.
5.Effects of monitored anesthesia care with deep sedation on gastrointestinal endoscopy
Bailin JIANG ; Liming ZHANG ; Yi FENG
Chinese Journal of Digestive Endoscopy 2017;34(3):197-199
Objective To explore effects of monitored anesthesia care (MAC) on gastrointestinal endoscopy.Methods All patients who underwent gastrointestinal endoscopy in Peking University People's Hospital from September 2010 to September 2015 were analyzed retrospectively and divided into two groups:the MAC group and control group by usage of MAC.Success rates of removal of foreign bodies by upper gastrointestinal endoscopy were compared between two groups during this period.Detection rates of ectopia of gastric mucosa in upper esophagus were compared between two groups from September 2014 to September 2015 when esophagogastroduodenoscopy was performed.The monthly cases of gastrointestinal endoscopies were compared between the two groups,which were separately collected from one MAC operating table and one routine operating table from September 2014 to September 2015.Results The success rate of removal of foreign bodies in the MAC group was higher than that in the control group (100.0% VS 89.7%,x2 =11.737,P=0.001).The detection rate of ectopia of gastric mucosa in upper esophagus in the MAC group was higher than that in the control group(4.3% VS 1.7%,x2 =58.751,P<0.001).The monthly cases of gastrointestinal endoscopies in the MAC group was higher than that in the control group(350.2±36.2 cases VS 213.2±27.9 cases,t =17.591,P<0.001).Conclusion The use of MAC for gastrointestinal endoscopy improves operating success rate,accuracy and operating time.MAC in gastrointestinal endoscopy can be recommended.
6.The present studies of the role of the aortic vascular smooth muscle apoptosis and Hippo-YAP signaling pathway in the development of aortic dissection
Wenjian JIANG ; Feng LAN ; Hongjia ZHANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2016;32(1):51-54
Aortic dissection is a kind of fatal cardiovascular disease, and the apoptosis of aortic vascular smooth muscle plays an important role in aortic dissection.The new discovered Hippo-YAP signal transduction pathway is significant in regulation of the function of vascular smooth muscle, and it can cause many cardiovascular diseases.This paper aims to review the present studies of the mechanism of the apoptosis of aortic vascular smooth muscle and Hippo-YAP signaling pathway in the pathogenesis of cardiovascular diseases, especially the aortic dissection.
7.Endoscopic treatment of septated chronic subdural hematoma With a report of 45 cases.
Wenchuan ZHANG ; Feng JIANG ; Jie MA
Chinese Journal of Minimally Invasive Surgery 2001;0(04):-
Objective To evaluate the therapeutic results of neuroendoscopy for the treatmentof of patients with septated Chronic Subdural Hematoma(SCHS). Methods 45 patients with SCSH were operated on under endoscope through a burrhole approach.neomembranes were resected by small microscissors.A closed drainage system was applied temporarily to ensure the efflux of the remaining hematoma. Results Forty-five cases were treated successfully.All patients had a sufficient or complete hematoma evacuation whithout recurrence of subdural hematoma.There was no subdural infection,bleeding,brainedema and cranial aerocele. Conclusions Neuroendoscopy is minimally invasive technique and have the advantages ot simple,effective,safe,less complication,less expensive and shorter hospitalization in the treatment of SCSH.
8.Effect of sodium nitroprusside sustained release on cognitive function, S-100βprotein and visinin-like protein 1 in pituitary tumor surgery patients
Huahui QIU ; Zenghui ZHANG ; Feng JIANG
Chinese Journal of Biochemical Pharmaceutics 2015;(6):83-85,88
Objective To investigate the effect of sodium nitroprusside sustained release on cognitive function, S-100βprotein and VILIP-1 in pituitary tumor surgery patients.Methods 156 cases of pituitary tumor patients were selected and divided into two groups according to random number table method,78 patients in each group.All patients underwent general anesthesia induction,the experimental group treated with 0.5~6 μg ( kg· min) infusion of sodium nitroprusside induced hypotension by micro pump at the beginning of operation.MMSE was used to determine the cognitive function of 2 groups of patients 1 day before operation and 2 days after operation,S-100βand VILIP-1 content were determined by ELISA before anesthesia,after surgery,and 0,12,24,48 h after operation.Results There was no statistical significance between the 2 groups in the incidence of postoperative cognitive dysfunction.Compared with control group, the operation time, bleeding volume and the recovery time of the experiment group were lower(P<0.05).S-100βprotein and VILIP-1 showed increased at first and then decreased at the peak of 24h;compared with the normal group, the levels of S-100βprotein and VILIP-1 of the cognitive impairment were higher ( P <0.05 ).Compared with the control group, the levels of S-100βprotein and VILIP-1 of the experiment group were lower(P <0.05).Conclusion Sodium nitroprusside sustained release controlled hypotension can reduce the level of cognitive disorder, patients of S-100βprotein and visinin-like protein 1 and has certain directive significance to the clinical.
9.Study of the Therapeutic Effects of Bushenshengsui I on Mice With Experimental Aplastic Anaemia
Jiang FENG ; Lin HONG ; Shumo ZHANG
China Pharmacy 2001;0(08):-
OBJECTIVE:To study the possible mechanism of Bushenshengsui I(BSSS I),a kind of compound Chinese herbs,in treatment of aplastic anaemiaMETHODS:The animal model of mice with aplastic anaemia was established by 60Co irradiationThe therapeutic effects of BSSS I on aplastic anaemia were observed with the changes of peripheral blood cell count,bone marrow GM-CFU-c and activities of blood IL-1,IL-2 and IL-6RESULTS:After treatment with BSSS I,the peripheral blood cell count,amount of bone marrow karyocyte and GM-CFU-c of bone marrow of the aplastic anaemia mice elevated markedly,and the blood IL-1 and IL-6 activities increased obviouslyThe levels of IL-6 increased to the level of normal and showed positive relationship with IL-1(r=0904)The levels of IL-2 of the treatment group showed a decrease but with no significant differencesCONCLUSION:The results showed that BSSS I may improve the function of hematopoiesis by elevating the peripheral blood cells and the amount of bone marrow karyocytes,accelerating GM-CFU-c of bone marrow,and through moderating the activities of IL-1,IL-2,IL-6
10.Clinical and pathological analysis of patients with primary mesangial proliferative glomerulonephritis in different genders
Yali ZHANG ; Jie FENG ; Shasha JIANG ; Jiping SUN ; Xueliang FENG
Clinical Medicine of China 2012;28(9):951-954
Objective To understand the differences between sexes in the clinical and pathological features of patients with mesangial proliferative glomerulonephritis(MPGS).MethodsOne hundred and five patients with MPGS admitted to our hospital were retrospectively studied in clinical and pathological aspects.Results( 1 ) The proportion of male patients were 75 of 105 ( 71.43 % ) and that of females were 30 of 105 ( 28.57% ) ; ( 2 ) The average age of the male patients was ( 40.25 ± 15.50 ) and that of the females was (36.23 ± 15.26) in year.There was no significant difference between the two groups( t =1.206,P =0.231 ) ;(3) There was no significant difference in duration of disease,hematuria,edema,hypertension prevalence and mean blood pressure( P > 0.05 ).The proportion of patients with hematuria was 56.19% (59/105).The males accounted for 69.33% ( 52/75 ) and the females were 63.33% ( 19/30 ) in the main clinical manifestations of nephrotic syndrome.There was no significant difference( x2 =0.352,P > 0.05 ) between the proportion of males and females; (4)Males and females groups had no significant difference( P > 0.05 )on levels of urinary protein,serum albumin,immunoglobulin,complement,urea nitrogen and serum creatinine.Complement decreased in 53 cases,accounting for 53% of all the participants.The proportion of male patients with renal insufficiency was 24.00% (18/75),and the proportion of females with renal insufficiency was 13.33% (4/30).There was no significant difference ( x2 =1.472,P > 0.05 )on the percentage of males and females with renal insufficiency.The mean value of urea nitrogen was higher than the normal levels ; (5) The proportion of male cases with different deposition of immune complexes was 93.06% (67/72),and the proportion in females were 92.86% (26/28) in the exception of 5 cases ( male 3 and female 2 ) with no glomeruli in immunofluorescence examination.No significant difference was found between the two groups( x2 =0.001,P > 0.05 ) ; ( 6 ) There was no significant gender differences( x2 =1.696,P > 0.05 ) found in risk assessment.ConclusionThe prevalence of MPGS is higher in male patients than in females,the main clinical manifestations of which were nephrotic syndrome.Patients were found to have a higher rate of hematuria,decreased complement C3,and renal dysfunction than the normal levels.There was no significant difference in gender on the clinical and pathological aspects of MPGS.