1.Observations on the Efficacy of Triple Needling at Muscle Insertions plus Moxibustion in Treating Acute Carpometacarpal Joint Injury
Shanghai Journal of Acupuncture and Moxibustion 2016;35(4):446-448
Objective To investigate the efficacy of triple needling at muscle insertions plus moxibustion in treating acute carpometacarpal joint injury. Method Forty patients were randomly allocated to acupuncture and medication groups, 20 cases each. The therapeutic effects were evaluated after one course of treatment. Result The total efficacy rate and the cure rate were 100.0%and 80.0%, respectively, in the acupuncture group and 90.0% and 50.0%, respectively, in the medication group. There were statistically significant differences in the total efficacy rate and the cure rate between the two groups (P<0.01). The VAS score decreased significantly in both groups of patients after treatment compared with before (P<0.01). The post-treatment VAS score was lower in the acupuncture group than in the medication group (P<0.01). Cooney wrist joint score increased in both groups after treatment compared with before (P<0.01). The post-treatment Cooney score was higher in the acupuncture group than in the medication group (P<0.01). Conclusion Triple needling at muscle insertions plus moxibustion has clinically a marked therapeutic effect on acute carpometacarpal joint injury.
2.International Business of Global Chemical Pharmaceutical Enterprises and Its Enlightenment on China
China Pharmacy 1991;0(06):-
OBJECTIVE: To explore strategies for Chinese chemical pharmaceutical enterprises in the practice of international business. METHODS: Based on the theory of international business, the international business of global chemical pharmaceutical enterprises was analyzed in terms of business time, real strength and business procedures, etc. RESULTS & CONCLUSION: The success of international business of the global chemical pharmaceutical enterprises is closely related to their long business time, real strength and the successful internationalization of the mix of investment,research & development, production and sales. Striving to carry out international business strategy, Chinese chemical pharmaceutical enterprises should draw advanced experiences by acting from improving management strategy, comprehensive competitive power, high grade products with high added value and making good use of the global resources.
5.Preliminary Study on Anticyclophilin A Auto-Antibodies in Sera of Patients with Psoriasis
Chinese Journal of Dermatology 2001;34(2):93-94
Objective To determine the level of anticyclophilin A auto-antibodies (ACA) in sera of patients with psoriasis. Methods Cyclophilin A (CyPA) was extracted and purified from bovine thymus. The level of anticyclophilin A auto-antibodies (ACA) was detected by enzyme-linked immunosorbent assay (ELISA) and immunoblotting test (IBT) in sera of patients with psoriasis. Results It was shown that the level of ACA was significantly higher in the sera of patients with psoriasis than those in control group (IBT:P<0.01,ELISA:P< 0.01). ACA was found to be positive in 41.3% of the patients by ELISA. In psoriatic group, the serum level of ACA was higher during the progressive stage than that in the stationary stage, however, no significant difference was observed (IBT:P>0.05,ELISA:P >0.05). Conclusion The results suggest that there is autoimmunological mechanism in the pathogenesis of psoriasis.
6.Predictors of one year mortality in the elderly patients with hip fracture following poststroke hemiplegla
Chinese Journal of Orthopaedic Trauma 2012;14(2):93-97
Objective To investigate predictors of one year mortality in the elderly patients with hip fracture following poststroke hemiplegia.MethodsA retrospective study was conducted to analyze clinical data of the elderly patients who had received surgery in our hospital from January 2000 to May 2007 forhip fractures.Patients in the poststroke hemiplegia group (group A) and the hemiplegia-free group (group B)were compared in terms of general characteristics.Predictors of one year mortality in group A were analyzed statistically.Variables to be analyzed included age,gender,American Society of Anesthesiologists(ASA) rating,preoperative comorbidity,fracture type,prefracture ambulatory status and cognitive ability,hospital stay,interval from injury to surgery,anaesthetic mode and operational mode. Results Altogether 1379 patients with a mean age of 76.4 ± 7.0 years (from 65 to 99 years) were eligible for the present investigation.Of them,101 were assigned into group A.There were significant differences between the 2 groups in ASA rating,number of preoperative comorbidity,prefracture ambulatory status and cognitive ability,hospital stay and one year survival ( P < 0.05).One year follow-up found 25 deaths in group A (mortality rate 24.8% ).Multiple logistic regression analysis showed that gender ( P =0.017),ASA rating ( P=0.009),prefracture ambulatory status ( P =0.000),chroic respiraory disease ( P =0.022) and number of preoperative comorbidity ( P =0.048) were risk factors associated with the one year mortality in group A.ConclusionsEldarly hip fracture patients with hemiplegia tend to have a longer hospital stay and a higher mortality rate than those without hemiplegia.Male gender,ASA rating ≥ Grade Ⅲ,number of preoperative comorbidity ≥ 3,chronic respiratory disease and weak prefracture ambulatory status are predictors of one year mortality in the elderly patients with hip fracture following poststroke hemiplegia.
7.IL-10 gene polymorphism with ulcerative colitis susceptibility and its influence on clinical outcomes
Chinese Journal of Immunology 2016;32(9):1369-1373
Objective:To study the correllation of genetic polymorphisms of IL-10 polymorphic loci with ulcerative colitis sus-ceptibility and its influence on clinical outcomes.Methods:A total of 80 patients with ulcerative colitis were selected as case group and the others by sex and age matched healthy subjects as control group according to the case-control study design.Peripheral venous blood samples were drawn and DNA was extracted from all subjects prior to treatment.PCR primers of -819T/C(rs1800871),-592A/C (rs1800872),-1082G/A(rs1800896) were designed for PCR amplification.The fragments produced from human genomic DNA were performed by restriction enzyme digestion of amplified PCR products,and further separated using agarose gel electrophoresis.Relative risk(OR) and 95%confidence interval(95%CI) were calculated by the Logistic regression,in order to evaluate the correlation of IL-10 gene polymorphism with susceptibility of ulcerative colitis and clinical outcomes.Results:(1)The distribution frequency of genotype AA,GG and AG of polymorphic loci rs1800896 in cases patients were significantly different from that in control group(P<0.01).(2) Compared to rs1800896 genotype AA,genotype GG were significantly associated with increased risk for ulcerative colitis(P<0.01)and the decreased clinical remission rate ( P<0.01 ).( 3 ) The distribution frequency of genotype CC, CT and TT of polymorphic loci rs1800871 were not significantly different between groups(P>0.05).(4)The distribution frequency of genotype AA,AC and CC of polymorphic loci rs1800872 were not significantly different between groups(P>0.05).Conclusion:IL-10 polymorphic loci rs1800896 genotype GG would be associated with increased susceptibility to ulcerative colitis,and poor prognosis of patients.