Adjuvants, Immunologic ; therapeutic use ; Animals ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Phytotherapy ; Systemic Inflammatory Response Syndrome ; complications ; drug therapy

Through learning philosophy,human beings can overcome the fear of death and gain the wisdom of life.With the rapid development of modem high-tech,some people advocate to pursue the immortality of individual life using science and technology.This is the most restless thoughts,originating from the false belief of dogmatic rationalism:with the development of science and technology,human beings are possible to fully grasp the mysteries of the nature (including human body).In fact,nature as well as human body is always hidden in infinite mystery.The pursuit of immortality is from the pursuit of meaning.Setting up morality,making contribution,and achieving glory by writing are the legitimate ways for human beings to pursuit immortality as cultural animals.One just can pursue immortality in the cultural sense,but cannot pursue the immortality of individual life.

Objective To introduce the development of an adjustable and bed- type table for pleural puncture and observe its clinical effect. Methods 100 patients who were to undergo pleural puncture were divided into the experimental group and the control group with 50 cases in each group.The experimen-tal group adopted the adjustable and bed-type table for pleural puncture, while the control group used the conventional method.The pulse,respiration and artery blood oxygen saturation degree were observed. The ef-feet of puncture was also compared. Results The pulse and respiration increased and the artery blood oxygen saturation degree decreased after puncture,which were significantly different between the two groups. One- time success rate of puncture,comfort degree and satisfaction degree of patients in the experimental group were better than those of the control group. Conclusions Adjustable and bed- type table for pleu-ral puncture can reduce the uncomfort of patients and increase the success rate of puncture and satisfaction degree of patients.

Dental Restoration, Permanent ; Humans ; Prosthesis Coloring

Acute Disease ; Aged, 80 and over ; Fibrin Fibrinogen Degradation Products ; analysis ; Humans ; Male ; Pulmonary Embolism

Objective To explore the causes and surgical management of acute gangrenous cholecvstitis(AGC)after endoscopic sphincterotomy(EST).Methods Clinical and pathological data of 1066 patients who underwent EST from June 2003 to January 2007 were analyzed retrospectively.ResultsAGC was complicated in 16 patients(16/1066,1.5%),who underwent emergency operations and no death occurred.During the follow-up period of 4 to 36 months,no infection or obstruction was found.Conclusion Difficuitv in EST manipulation and biliary obstrucion might play a leading role in AGC after EST,and early surgical intervention is effective.

Objective To study the correlation between human leukocyte antigen (HLA)-DRB1 alleles and anti neutrophil cytoplasmatic antibodies (ANCA) in Han and Uygur ulcerative colitis (UC)patients in Xinjiang region.Methods The serum ANCA was determined by indirect immunofluorescence assay in 62 Uygur UC patients,58 Han UC patients,188 Uygur and 184 Han healthy control individuals.HLA-DRB1 typing was performed by polymerase chain reaction-sequence based typing (PCR-SBT).The allele frequency of HLA-DRB1 was compared in ANCA positive and negative Han and Uygur patients as well as healthy controls.Stratified analysis was performed according to UC clinical type,severity and involvement.SPSS 17.0 software was applied for x2 test.Once P＜0.05,the odds ratio (OR) and 95％ confidence intervals (95％CI) was calculated.Results The positive rate of ANCA in Uygur UC patients (53.2％,33/62) was significantly higher than that of Han patients (34.5％,20/58) and the difference was statistically significant (x2=4.269,P =0.045).In Uygur,the gene frequency of HLA-DRB1 * 13 in ANCA positive UC patients (0.202)was significantly higher than that of ANCA negative patients (0.017) (x2 =10.092,P=0.016,OR=16.000,95％CI:2.892 to 88.524) and healthy controls (0.075) (x2=9.351,P＝0.040,OR=3.407,95％CI:1.666 to 6.971).The gene frequency of HLA-DRB1 * 13 in ANCA positive pancolitis type UC patients (9/15) was significantly higher than that of ANCA negative pancolitis type UC patients (1/14) and the difference was statistically significant (x2=8.955,P =0.040,OR =19.500,95％CI:2.787 to 136.461).However,in Han patients,there were no significant differences of HLA-DRB1 alleles frequencies among ANCA positive patients,ANCA negative patients and healthy controls (all P＞0.05),and the results of stratified analysis were same.Conclusions In Uygur UC patients of Xinjiang region,HLA-DRB1 * 13 may correlated with ANCA and with ANCA of pancolitis type UC patients.There is no such correlation in Han patients of Xinjiang region.

Recent studies about the GCT are focusing on searching for new standards and indexes to prognose the biological behavior of the GCT because of the traditional standards and indexes have been realized often not agree with to the clinic. we review the lately research about the biological behavior of the GCT, then analyse and sum up the correlative indexes that could be significant in studying the prognosis of the GCT.

Objective The aim of this paper is to develop a holistic mathematical model to quantify the correlation between skin thermal sensation and noxious stimuli,since skin thermal pain is one of the most common problems in everyday life and the understanding of the underlying physical mechanisms is still not clear.Methods The model is developed by considering the biothermomechanical behaviour of skin tissue and by incorporating the current understanding of biophysical and neurophysiological mechanisms of pain sensation.Results The proposed model consisted of three interconnected sub-models: peripheral modulation of noxious stimuli,which converts the energy from a noxious thermal stimulus into electrical energy via nerve impulses;transmission,which transports these neural signals from the site of transduction in the skin to the spinal cord and brain;and modulation and perception in the spinal cord and brain.The model predictions agree well with existing experimental data.Conclusion With this model,a direct relationship has been built between the level of thermal pain sensation and the character of noxious stimuli.

Objective To evaluate the clinical results of phacoemulsification combined with pars plana vitrectomy for eyes with cataract and proliferative diabetic retinopathy. Design Non-controlled retrospective case series study. Participants 123 eyes with proliferative diabetic retinopathy (PDR) and cataract. Methods Phacoemulsification,posterior chamber intraocular lens (PCIOL) implantation combined with pars plana vitrectomy were done in 123 eyes with proliferative diabetic retinopathy (PDR) and cataract. Postoperative vision,number of secondary procedures and surgical complications were analyzed. Main Outcome Measures Postoperative visual improvement and associated complications. Results All 123 eyes underwent combined surgery. The average follow-up was 10 months. 99 eyes (81%) experienced postoperative vision improvement of varying degrees. Vision improved by 2 lines or more in 93 eyes (76%). No apparent corneal edema or corneal decompensation were encountered. One patient with type 1 diabetes developed neovascular glaucoma 6 months after surgery. Retinal detachment occurred in 1 eye and reoperated. Vitreous hemorrhage requiring secondary procedure happened in 4 eyes. All 24 eyes (19%) without vision improvement were found to be with diabetic maculopathy. Conclusions Phacoemulsification combined with pars plana vitrectomy can be used as an effective surgical tool to improve visions in patients with PDR and cataract. Diabetic maculopathy is the major cause of poor visual improvement. (Ophthalmol CHN ,2006,15: 198-201)