1.The association of endocrine-disrupting chemicals exposure, sociodemographic factors, and polycystic ovarian syndrome among reproductive-aged nonpregnant women at the Philippine General Hospital: A case–control study
Erlidia Flores Llamas-Clark ; John Robert Carabeo Medina ; aria Esterlita Tagle Villanueva-Uy ; Francisco M. Heralde III ; Maria Stephanie Fay Samadan Cagayan ; Paulyn Jean Buenaflor Rosell-Ubial ; Michael C. Velarde
Philippine Journal of Obstetrics and Gynecology 2024;48(3):151-161
BACKGROUND:
Polycystic ovarian syndrome (PCOS) is a prevalent condition affecting women of reproductive age, characterized by metabolic, endocrine, and reproductive disturbances including insulin resistance, abnormal uterine bleeding, infertility, and hyperandrogenism, and is associated with diabetes and cardiovascular disease. The etiology of PCOS is unclear and exposure to endocrine-disrupting chemicals (EDCs) present in everyday products may play a role by disrupting hormonal pathways.
OBJECTIVES:
To determine the association between exposure to EDC-containing products, sociodemographic factors, and PCOS diagnosis among nonpregnant reproductive-aged women.
MATERIALS AND METHODS:
A survey assessed the frequency of EDC exposure in homes and workplaces. The Rotterdam Criteria were used for the diagnosis of PCO features with clinical history and ultrasound. The association between PCOS and EDC exposure was determined using Chi-square and logistic regression analysis.
RESULTS:
The study identified significant sociodemographic factors associated with PCOS (P < 0.001) including age, civil status, and household income. Increased likelihood of PCOS was linked to frequent use of scented candles (odds ratio [OR] = 2.07), cleaning sprays (OR = 2.28), and floor polish (OR = 2.07), exposure to new upholstered furniture (OR = 4.00), thermal receipts (OR = 2.16), and consumption of microwaved and processed foods (OR = 2.60), as well as water sourced from wells (OR = 7.69). Additional associations were found with access to public markets (OR = 0.26) and the use of paper food wrappers (OR = 1.72).
CONCLUSION
These findings suggest that frequent exposure to EDC-containing products and certain sociodemographic factors may contribute to the development of PCOS among women of reproductive age. Results underscore the importance of reducing exposure to EDCs to prevent or mitigate the development of PCOS and other reproductive consequences.
Female
2.Evaluation of female infertility
Philippine Journal of Reproductive Endocrinology and Infertility 2007;4(1):19-24
This paper will focus only on the recommendations or guidelines on the evaluation for female infertility. Most of the recommendations were based on the Fertility Assessment and Treatment for People with Fertility Problems Guideline by the National Institute for Clinical Excellence.
Human
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Female
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INFERTILITY, FEMALE
3.Malignancies of the female genital organs, 10 years experience a study of incidence and histopathology.
Tae Sung LEE ; Ki Hyun CHO ; Jung Geol AHN ; Hyeong Jong LEE ; Soon Do CHA ; Tak LEE ; Young Wook SUH
Korean Journal of Obstetrics and Gynecology 1991;34(10):1425-1433
No abstract available.
Female
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Female*
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Genitalia, Female*
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Humans
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Incidence*
4.Female Adnexal Tumor Probable Wolffian Origin: Report of a case.
Soo Kyong CHUNG ; Seok Jin GANG ; Byoung Kee KIM ; Sun Moo KIM
Korean Journal of Pathology 1987;21(1):45-48
The clinical and pathological features of a distinctive female adnexal tumor of probable Wolffian origin (FATWO) are presented. As fat as our knowledge is concerned, no report on the FATWO has been published in Korea. In April, 1986, we experienced a case of FATWO that arose within the leaf of the right broad ligament in a 68 years old female. Clinical data and histopathological findings of the case were discussed and a brief review of the literature on this entity was made.
Female
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Humans
5.Renal Cell Carcinoma Associated with Rhabdomyosarcomatous Component: Report of a case.
Mee Soo CHANG ; Mi Kyung JEE ; Kyo Young LEE ; Sang In SHIM ; Sun Moo KIM
Korean Journal of Pathology 1987;21(1):40-44
Renal cell carcinoma, intimately associated with a sarcomatous component, is a rare malignant renal tumor. There is disagreement whether these represent true sarcomas or are sarcomatoid metaplasia. Therefore, this sarcomatous component is at times still a troublesome problem for pathologists. In March, 1986, we experienced a case of renal cell carcinoma associated with rhabdomyosarcomatous component in 47 year-old woman who had a rapidly enlarged, palpable abdominal mass. Grossly, a spherical renal cell carcinoma, 17x14x10 cm, in upper and middle portions of the right kidney showed extension through the renal capsule into the perirenal fat. Area of myxoid change was evident in the reanl cell carcinoma, with extensive hemorrhagic necrosis. Microscopically, in the myxoid area, there was malignant spindle cell proliferation in which many rhabdomyoblasts showing distinct cross striation could be demonstrated. This rhabdomyosarcomatous component intermixed with renal cell carcinoma of clear cell type could be also identified in the focal area.
Female
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Humans
6.A Case of Recurrent Intestinal Pseudo-obstruction in a Patient with Systemic Lupus Erythematosus.
Yun Jung KIM ; Jeong Ha PARK ; Kyu Sig HWANG ; Sang Cheol BAE
The Journal of the Korean Rheumatism Association 2008;15(1):81-86
Gastrointestinal manifestations are common in systemic lupus erythematosus (SLE). Intestinal pseudo-obstruction (IpO) is a rare, poorly understood and recently recognized gastrointestinal manifestation of SLE. We report a 26-year-old female with SLE for 3 years. 10 months ago, IpO was diagnosed first, and it was responded well to high-dose steroid therapy. After then, oral prednisolone and azathioprine were administered, but the patient had been lost to follow up until recurrence of IpO. She was admitted with diffuse abdominal pain, distension, frequent vomiting, and intermittent dysuria due to recurrent IpO accompanied with bilateral ureterohydronephrosis. Despite of high dose steroid therapy, her symptom and imaging findings were not improved. The patient was treated with pulses of cyclophosphamide, and then the patient's symptoms and signs were gradually subsided. Three weeks following cyclophosphamide therapy, she was able to eat without vomiting and following abdominal CT showed nearly complete resolution of diffuse intestinal distension and bilateral ureterohydronephrosis. High level of awareness of IpO in SLE and appropriate medical treatment is needed to prevent unnecessary surgical treatment. And if this complication is refractory to corticosteroid, active immunosuppressive therapy, such as cyclophosphamide, should be considered.
Female
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Humans
7.An Anesthetic Experience for the Removal of Huge Ovarian Cystic Tumor .
Cheol Seung LEE ; In Ho HA ; Jung Sung HA
Korean Journal of Anesthesiology 1982;15(4):631-635
In removing a huge abdominal mass, we often observe acute hemodynamic changes, For adequate anesthetic management we must carefully observe CVP, MAP, ECG and pulse rate ect. The authons report an an anethetic experience in the removal of huge a ovarian cystic mass. The patient was 29year old female. Under contianous monitoring of CVP, MAP, ECG, pulse rate and fluid administration, the patient tolerated the anesthetic period well. The total weight of the tumor mass was about 34kg, which waa composed of 30L cystic fluid and 4kg of solid maas.
Female
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Humans
8.Concenteric Chorioretinal Atrophy after Photodynamic Therapy.
Dae Hyun SON ; Sung Won CHO ; Soon Hyun KIM
Journal of the Korean Ophthalmological Society 2005;46(7):1240-1245
PURPOSE: To report a case of chorioretinal atrophy after photodynamic therapy to subfoveal choroidal neovascular membrane. METHODS: We followed up the photodynamic treatment to a 57-year-old woman who complained of the falling of vision in her right eye for 2 months and was diagnosed with subfoveal choroidal neovascular membrane at our institution. Since the size of neovascular membrane increased 3 month after the first photodynamic treatment, the patient underwent retreatment. Concentric chorioretinal atrophy developed around the laser applied site 3 months after retreatment, and enlargement of the atrophy area occurred 2 years later. In multifocal electroretinography, the retinal function of the chorioretinal atrophic eye was not decreased compared with the other eye. RESULTS: The choroids collateral circulation damage or direct drug photochemical effect was thought to be the cause of the chorioretinal atrophy after photodynamic treatment at the laser applied site but there is no functional decline of the atrophic retina.
Female
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Humans
10.The Urinary Fluoride Concentration and Periodontal Condition in Postmenopausal Osteoporotic Women.
The Journal of the Korean Academy of Periodontology 1999;29(4):837-845
There were few reports about the fluoride concentration in bone and osteoporotic women. This study was designed to evaluate the relationship between the urinary fluoride concentration and periodontal condition in osteoporotic old women. Twenty-eight postmenopausal women(Test group) and twenty-one premenopausal women(Control group) were examined. Bone mineral density(BMD) of lumbar spine(L2-L4) was measured by dual energy X-ray absorptiometry(DEXA). The urine samples were collected at early morning and determined with the help of a fluoride-specific electrode and Tisab-bufferd samples. The results were as follows. 1.The mean urinary fluoride concentration in test and control group showed statistically no difference. 2.The bone mineral density(BMD) of the spine in test group was significantly lower than control group(p<0.05). 3.The significant negative correlation was found between BMD level and age after menopause(p<0.001, gamma=-0.526). 4.The urinary fluoride concentration was not correlated with age, age after menopause and bone mineral density. 5.The urinary fluoride concentration was not correlated with periodontal condition.
Female
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Humans