1.The association of endocrine-disrupting chemicals exposure, sociodemographic factors, and polycystic ovarian syndrome among reproductive-aged nonpregnant women at the Philippine General Hospital: A case–control study
Erlidia Flores Llamas-Clark ; John Robert Carabeo Medina ; aria Esterlita Tagle Villanueva-Uy ; Francisco M. Heralde III ; Maria Stephanie Fay Samadan Cagayan ; Paulyn Jean Buenaflor Rosell-Ubial ; Michael C. Velarde
Philippine Journal of Obstetrics and Gynecology 2024;48(3):151-161
BACKGROUND:
Polycystic ovarian syndrome (PCOS) is a prevalent condition affecting women of reproductive age, characterized by metabolic, endocrine, and reproductive disturbances including insulin resistance, abnormal uterine bleeding, infertility, and hyperandrogenism, and is associated with diabetes and cardiovascular disease. The etiology of PCOS is unclear and exposure to endocrine-disrupting chemicals (EDCs) present in everyday products may play a role by disrupting hormonal pathways.
OBJECTIVES:
To determine the association between exposure to EDC-containing products, sociodemographic factors, and PCOS diagnosis among nonpregnant reproductive-aged women.
MATERIALS AND METHODS:
A survey assessed the frequency of EDC exposure in homes and workplaces. The Rotterdam Criteria were used for the diagnosis of PCO features with clinical history and ultrasound. The association between PCOS and EDC exposure was determined using Chi-square and logistic regression analysis.
RESULTS:
The study identified significant sociodemographic factors associated with PCOS (P < 0.001) including age, civil status, and household income. Increased likelihood of PCOS was linked to frequent use of scented candles (odds ratio [OR] = 2.07), cleaning sprays (OR = 2.28), and floor polish (OR = 2.07), exposure to new upholstered furniture (OR = 4.00), thermal receipts (OR = 2.16), and consumption of microwaved and processed foods (OR = 2.60), as well as water sourced from wells (OR = 7.69). Additional associations were found with access to public markets (OR = 0.26) and the use of paper food wrappers (OR = 1.72).
CONCLUSION
These findings suggest that frequent exposure to EDC-containing products and certain sociodemographic factors may contribute to the development of PCOS among women of reproductive age. Results underscore the importance of reducing exposure to EDCs to prevent or mitigate the development of PCOS and other reproductive consequences.
Female
2.Evaluation of female infertility
Philippine Journal of Reproductive Endocrinology and Infertility 2007;4(1):19-24
This paper will focus only on the recommendations or guidelines on the evaluation for female infertility. Most of the recommendations were based on the Fertility Assessment and Treatment for People with Fertility Problems Guideline by the National Institute for Clinical Excellence.
Human
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Female
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INFERTILITY, FEMALE
3.Malignancies of the female genital organs, 10 years experience a study of incidence and histopathology.
Tae Sung LEE ; Ki Hyun CHO ; Jung Geol AHN ; Hyeong Jong LEE ; Soon Do CHA ; Tak LEE ; Young Wook SUH
Korean Journal of Obstetrics and Gynecology 1991;34(10):1425-1433
No abstract available.
Female
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Female*
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Genitalia, Female*
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Humans
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Incidence*
5.Submucosal Gastric Actinomycosis in a Hematemesis Patient.
Nae Sung JANG ; Dong Geol YU ; Hae Chang JO ; Byung Jo BAE
Journal of the Korean Surgical Society 2001;60(3):345-348
We experienced a case of submucosal gastric actinomycosis, presenting as bleeding. The 65-year-old woman had a symptom of epigastric pain, without any other intra-abdominal disease entity. A gastrofiberscopic study demonstrated a submucosal mass lesion with bleeding at the fundus. Because of the bleeding, laparotomy was undertaken, and a abscess containing a large mass was found at the gastric fundus, and total gastrectomy undertaken. Histological examination revealed a giant acute ulcer with a submucosal abscess due to actinomycosis. Because of its rarity, submucosal gastric actinomycosis is an entity overlooked by most surgeons. We report upon this case of submucosal gastric actinomycosis and include a review of the literature.
Female
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Humans
6.Reduction Surgery for Giant Breast.
Journal of the Korean Surgical Society 2001;60(3):264-267
PURPOSE: Women with large breasts suffer from both physical embarrassment and physical discomfort. Recently, partially due to socioeconomic development, growing numbers of woman with large breasts have sought reduction surgery, which previously had not been popular in Korea. At this time, a proper evaluation of the operation is required in order to promote the procedure. METHODS: Case files of 60 reduction operations using the inferior pedicle flap method for the reduction of large breasts were clinically reviewed. RESULTS: The patients were aged 19~65 (mean 34.5) years. The primary reasons for surgery were self-consciousness, shoulder/neck/back pain, wet skinfold/eczema and intractable mastalgia. Breast parenchymal pattern analysis by mammography revealed relatively a high frequency of dysplastic change (DY) among women with intractable breast pain, which was nearly entirely relieved by reduction surgery. The nipple-areolar complex were saved with inferior dermal pedicle flaps without any occurrence of necrosis. An average of 350 (range 50~800) grams of tissue from each breast was removed. There were no blood transfusions and significant postoperative complications were rare, although some patients complained of hypertrophic scars. CONCLUSION: Postoperative results were sufficiently satifactory to consider reduction surgery for inappropriately large breasts as a rehabilitative method.
Female
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Humans
7.Female Adnexal Tumor Probable Wolffian Origin: Report of a case.
Soo Kyong CHUNG ; Seok Jin GANG ; Byoung Kee KIM ; Sun Moo KIM
Korean Journal of Pathology 1987;21(1):45-48
The clinical and pathological features of a distinctive female adnexal tumor of probable Wolffian origin (FATWO) are presented. As fat as our knowledge is concerned, no report on the FATWO has been published in Korea. In April, 1986, we experienced a case of FATWO that arose within the leaf of the right broad ligament in a 68 years old female. Clinical data and histopathological findings of the case were discussed and a brief review of the literature on this entity was made.
Female
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Humans
8.Renal Cell Carcinoma Associated with Rhabdomyosarcomatous Component: Report of a case.
Mee Soo CHANG ; Mi Kyung JEE ; Kyo Young LEE ; Sang In SHIM ; Sun Moo KIM
Korean Journal of Pathology 1987;21(1):40-44
Renal cell carcinoma, intimately associated with a sarcomatous component, is a rare malignant renal tumor. There is disagreement whether these represent true sarcomas or are sarcomatoid metaplasia. Therefore, this sarcomatous component is at times still a troublesome problem for pathologists. In March, 1986, we experienced a case of renal cell carcinoma associated with rhabdomyosarcomatous component in 47 year-old woman who had a rapidly enlarged, palpable abdominal mass. Grossly, a spherical renal cell carcinoma, 17x14x10 cm, in upper and middle portions of the right kidney showed extension through the renal capsule into the perirenal fat. Area of myxoid change was evident in the reanl cell carcinoma, with extensive hemorrhagic necrosis. Microscopically, in the myxoid area, there was malignant spindle cell proliferation in which many rhabdomyoblasts showing distinct cross striation could be demonstrated. This rhabdomyosarcomatous component intermixed with renal cell carcinoma of clear cell type could be also identified in the focal area.
Female
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Humans
9.Angiofollicular Lymph Node Hyperplasia(Castleman's disease): 3 cases report.
Jeong Hee PARK ; Gil Ro HAN ; Hee Jin CHANG ; Jin Hee SOHN ; Jung Il SUH
Korean Journal of Pathology 1992;26(3):298-305
Angiofollicular lymph node hyperplasia(AFLNH) was first described in 1956 by Castleman et al. It was initially reported as a solitary mediastinal mass but multicentric and extranodal disease is now well known. Histologically two distinct variants, e.g. the hyaline vascular type and the plasma cell type, of AFLNH are recognized. And the plasma cell type is typically associated with clinical syndrome consisting of fever, anemia, elevated erythrocyte sedimentation rate and polyclonal hypergammaglobulinemia. Recently, we experineced three cases of AFLNH. Histologically, two cases were hyaline vascular type, that were presented as a right supraclavicular mass of 49-year-old female, and as an anterior mediastinal mass of 53-year-old female. The remaining one case was plasma cell type that was presented as a left axillary mass of 63-year-old male. The former two cases showed typical features of hyaline vascular type but in case 1, exuberant proliferation of hyalinized vessels of capillary size was characteristic feature. The latter case of plasma cell type characteristically showed clinical syndrome consisting of fever, hypoalbuminemia, polyclonal hypergammaglobulinemia. All cases were presented as a single mass and they were well after surgical excision.
Female
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Humans