Objective To understand the characteristics and related factors of adverse reactions (ADR) of anti-tuberculosis drugs among Zhuang nationality patients with smear-positive pulmonary tuberculosis (TB) and to provide basis to ADR control.Methods During Dec 2007 to May 2008,408smear-positive pulmonary TB cases of Zhuang nationality in 14 counties were selected by simple random sampling,and followed up for 6-8 months.Questionnaires were performed and liver/renal functions were tested during the research.Data were analyzed by chi square test and Logistic regression model.Results The incidence of ADR of Zhuang nationality people was 17.2％,which was higher than national level ( 12.62 ％ ).The incidence of allergic reaction was highest of all ADR ( 5.9 ％ ) and the incidences among different types of ADR were significantly different ( x2 =36.9,P=0.000).Serious ADR types were allergic reaction,gastrointestinal reaction,liver damage,nerve damage and kidney damage.And 24.3 ％ of the cases had two or three kinds of ADR.ADR occurred at the median of 21.5th day of anti-TB treatment,and the gastrointestinal reaction occurred the earliest (6th day).81.4 ％ of the ADR occurred in the first 2 months of anti-TB treatment.The rates of drug withdrawal and interruption were 11.5 ％ and 9.2 ％,respectively.Liver damage and nerve damage were the main causes of treatment withdrawal and interruption.Multiple factor non-conditional Logistic regression analysis showed that the ADR was correlated with age and the risk of ADR in ≥60years old patients was 3.3 times of that in 14-34 years old patients (OR=3.275,P=0.006).Thus,ADR incidence was increased with aging.Conclusions The incidence of ADR is higher in Zhuang nationality patients than that in general patient population.ADR monitoring and intervention must be strengthened in high-risk groups during high-risk period to reduce the adverse effect of anti-TBtreatment.

Objective To analyze the transformation situation of the tuberculosis (TB) diagnosis and treatment mode in 18 coun-ties(cities) of Guangxi and to explore the countermeasure for perfecting the TB control service system in Guangxi .Methods The self-designed questionnaire was adopted to retrospectively investigate the transformation situation of the TB diagnosis and treatment mode in 18 counties(cities) .Results In the 18 counties(cities) ,there were 8 counties(cities) ,accounted for 44 .4% ,with the trans-formation reason of the qualification was not completed in the original agency;there were 16 counties (cities ) ,accounted for 88 .9% ,with issuing the formal documents and arranging relevant work by the local health bureau before the transformation ;the number of full-time TB staff was reduced in 14 counties(cities) ,accounted for 77 .8% ,after the transformation ;there were 8 coun-ties(cities) ,accounted for 44 .4% ,set up the independent TB outpatient in the designated hospital ;there were 4 counties(cities) ,ac-counted for 22 .2% ,received the evaluation of very goodandgoodfor the TB control work after the transformation .Conclusion The health administrative department should actively promote the counties (cities) without the completed medical qualification to transform the TB diagnosis and treatment mode and coordinate the related works to carry out smoothly .

Taxillus chinensis,belonging to hemiparasitic herbal medicine and featuring its wild host range,is used for relief from rheumatic conditions,reinforcement of liver and kidney,strengthening of tendon and bone,and prevention of abortion.It showed that host trees presented significant impacts on the quality of Taxillus chinensis in the modern researches.In this study,both domestic and foreign published articles over Taxillus chinensis from various host trees were reviewed to summarized its herbalogy,chemical constituents,toxicity,and pharmacological action.In regard to the influences on the quality of medicinal materials,ideas and references for the quality control of Taxillus chinensis were provided by analyzing the quality of Taxillus chinensis impacted by hosts.