1.Fermentation with microorganism for indigo
Tai YANG ; Yonghong WANG ; Feiyi XU ; Ming YANG ; Runchun XU ; Qilin SUN
Chinese Traditional Patent Medicine 1992;0(08):-
AIM: To apply the natural fermentation technology to produce indigo. METHODS: Fresh leaves of conehead were put in water and let its ferment naturally, then add lime to fermentation liquor to naturalize,indigo content was determined by HPLC. RESULTS: Fermentative temperature at 28 ℃ and oxygen supply were most important condition. CONCLUSION: Fungi can be successfully applied to indigo production.
2.Mathematical Model of Tumor Growth in Radiotherapy and Radiosensitivity Analysis
Meng ZHANG ; Gaiping ZHAO ; Feiyi XIA ; Haifei XU ; Xiaoli YU
Journal of Medical Biomechanics 2022;37(2):E292-E298
Objective To establish a mathematical model of tumor growth and invasion under radiotherapy, so as to numerically simulate the effect of radiotherapy on tumor growth and make sensitivity analysis.Methods The mathematical model of tumor growth and invasion with time evolution before and after radiotherapy was established. The model included four key variables in the process of tumor invasion: tumor cells, extracellular matrix (ECM), matrix-degradative enzymes (MDEs) and oxygen. The linear quadratic (LQ) model was used to simulate the survival probability of tumor cells after radiotherapy, and the effects of different radiotherapy schemes and radiotherapy coefficients on the treatment effect were discussed. Traditional radiotherapy and intraoperative targeted radiotherapy were compared.Results Under the premise of constant total dose, the results of radiotherapy were directly proportional to the radiotherapy coefficient, but not related to the radiotherapy frequency; the therapeutic effect of intraoperative targeted radiotherapy was better than that of standard treatment.Conclusions Simulation results are basically consistent with clinical experimental results. As a more efficient treatment method, intraoperative targeted radiotherapy can provide new ideas for clinical tumor treatment.
3.Finite Element Analysis on Biomechanical Properties of Unicompartmental Knee Arthroplasty in ACL Fracture of the Knee Joint
Pengxiang LI ; Gaiping ZHAO ; Feiyi XIA ; Jiajing YANG ; Haifei XU ; Tong MA ; Yihui TU
Journal of Medical Biomechanics 2020;35(1):E070-E076
Department of Orthopedics, Yang Pu Hospital Affiliated to Tongji University,