1.Characteristic of cerebrovascular pathological changes in cerebral infarction patients accompanied with hyperhomocysteinemia
Journal of Clinical Neurology 2017;30(4):278-280
Objective To compared the characteristics of cerebrovascular pathological changes in cerebral infarction patients accompanied with hyperhomocysteinemia (HHcy) and primary hypertension.Methods The level of homocysteine (Hcy) of 258 cerebral infarction patients with primary hypertension were detected, and patients were divided into H type hypertension group and hypertension group according to the level of Hcy.The cerebrovascular pathological changes were observed by DSA.Results There were 112 cases in H type hypertension group, and 146 cases in hypertension group.There had no significant difference between the two groups in gender, age, systolic pressure, diastolic pressure, and the rates of drinking and smoking (all P>0.05).Internal carotid artery (ICA) and middle cerebral artery (MCA) were involvements, and it was mainly with intracranial artery stenosis in the two groups.Compared with hypertension group, the rates of intracranial vessel lesion and severe cerebrovascular stenosis in H type hypertension group were significantly increased, and the rate of collateral vessels was significantly decreased(all P<0.05).Conclusion The stenosis of cerebrovascular seems much more narrower, heavier, and have less collateral circulation in cerebral infarction patients with H type hypertension.
2.Explore the Researching Thoughts of Senile Dementia
International Journal of Traditional Chinese Medicine 2009;31(1):19-
This article reviewed hot spot and problems in the research of the senile dementia,and proposal the researching thoughts and the tentative treament plan of this disease.
3.An Algorithm for Microcirculatory Blood Flow Velocity Measurement Based on Trace Orientation in Spatiotemporal Image.
Journal of Biomedical Engineering 2015;32(2):446-450
The velocity of blood in vessels is an important indicator that reflects the microcirculatory status. The core of the measurement technology, which is based on spatiotemporal (ST) image, is to map the cell motion trace to the two-dimensional ST image, and transfer the measurement of flow velocity to the detection of trace orientation in ST image. This paper proposes a trace orientation measurement algorithm is based on Randomized Hough Transformation and projection transformation, and it is able to estimate trace orientation and flow velocity in noisy ST images. Experiments showed that the agreement between the results by manual and by the proposed algorithm reached over 90%.
Algorithms
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Blood Flow Velocity
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Humans
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Microcirculation
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Spatio-Temporal Analysis
4.Clinical advancement of aromatase inhibitors in the therapy for human breast cancer
Fei FEI ; Jinsong LU ; Zhimin SHAO ;
China Oncology 1998;0(01):-
We review the proceedings on the methods of how the aromatase inhibitor maintains its function, the recently developed drugs and the progress in the field of endocrine therapy for human breast cancer
6.Clinical characteristics and salvage treatment for recurrent nasopharyngeal carcinoma.
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(3):261-264
Adult
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Aged
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Carcinoma
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Humans
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Middle Aged
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Nasopharyngeal Neoplasms
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diagnosis
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pathology
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therapy
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Neoplasm Recurrence, Local
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therapy
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Salvage Therapy
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Young Adult
7.A comparison study of laparoscopic versus open liver lobectomy (segmentectomy) for hepatocellular carcinoma
Bangyu LU ; Wenqi LU ; Fei HUANG
Chinese Journal of Minimally Invasive Surgery 2005;0(07):-
Objective To investigate short-term effects of laparoscopic liver lobectomy for the treatment of hepatocellular carcinoma. Methods A comparison was made between 17 cases of laparoscopic liver lobectomy (segmentectomy) (Laparoscopic Group) and 22 cases of open hepatectomy (Open Group) from January 2001 to June 2004. The operative time, blood loss, blood transfusion amount, liver functions and blood picture before and after the surgery, and complications between the two groups were compared respectively. Results The operative time was longer in the Laparoscopic Group (median, 300 min) than in the Open Group (median, 145 min) ( u =107.05, P =0.023). Both groups presented a similar appearance in the blood loss and the blood transfusion amount. Serum levels of bilirubin and ALT varied within narrower limits in the Laparoscopic Group than in the Open Group. No significant difference was seen in blood pictures before and after the surgery in both groups. No complications happened in the Laparoscopic Group, whereas 4 cases of complications were observed in the Open Group (1 case of incision infection, 1 case of hydrothorax, 1 case of subphrenic dropsy, and 1 case of postoperative bleeding). Conclusions Laparoscopic liver lobectomy (segmentectomy) for hepatocellular carcinoma is minimally invasive, safe and effective.
8.Application of three-dimensional contrast-enhanced MR angiography in the diagnosis and treatment of aortic coarctation
Qi LIU ; Jianping LU ; Fei WANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(06):-
Objective To evaluate the clinical value of three-dimensional contrast-enhanced MR angiography (3D CE-MRA) in the diagnosis and treatment of aortic coarctation. Methods Twenty-one patients with aortic coarctation underwent 3D CE-MRA with a 3D FLASH sequence after injection of 0.2 mmol Gd-DTPA per kg b. w. The source images were subtracted and transferred to computer workstation subsequently post-procession. In six patients, cardioangiography was performed simultaneously. The diagnoses of all patients of them were proven by surgery. Results There were 6 cases (28.6%) of simple type of aortic coarctation and 15 (71.4%) accompanied other cardiovascular abnormalities. 3D CE-MRA could directly demonstrate the stenotic location, degree, extent and extracardiac vascular abnormalities, which accorded with surgical findings. The depiction of the entirety and collateral vessel formation was very helpful for surgery. It can be easier for pre- and post- operative evaluation. Conclusion 3D CE-MRA is a noninvasive and accurate technique in the diagnosis of aortic coarctation. It could replace the cardioangiography for extracardiac vascular abnormalities, and may be one of the first choice examinations.
9.Investigation of psychological status of the AIDS affected orphans settled in Sunshine Homestead
Qiwen XIE ; Fei WANG ; Jiakun LU
Chinese Journal of AIDS & STD 2007;0(03):-
Objective To understand the psychological status of the AIDS affected orphans in Henan Sunshine Homestead.Methods One hundred orphans from three Henan Sunshine Homesteads were investigated by questionnaire and depth-interviews.Results The study showed that the AIDS affected orphans were satisfied with their present living conditions in general,but still had some dissatisfaction.They valued peer relations,but were passive to contact strangers,and also felt lacking of care from the elderly.Nearly 70% of the orphans were some what introverted in nature,and some were in lack of thankful heart to managers of the Homestead and their patrons.
10.Research advances in adult hepatic progenitor cells
Fei LI ; Zhenzeng MA ; Lungen LU
Journal of Clinical Hepatology 2017;33(5):994-997
The liver has a strong regenerative capacity,and in case of acute injury,the proliferation of mature hepatocytes helps to complete liver regeneration.However,in case of chronic injury,the proliferative capacity of mature hepatocytes is damaged or exhausted,and the activation,proliferation,and differentiation of hepatic progenitor cells are involved in liver regeneration.This article summarizes the characteristics and origins of hepatic progenitor cells,their role in tissue repair after liver injury and development of liver cancer,and potentials and problems of cell transplantation in the treatment of liver diseases.It is pointed out that an understanding of the biological characteristics of hepatic progenitor cells,their role in liver injury and liver cancer,and related pathogenesis helps with the treatment of liver diseases.