Objective:To establish a method for the uncertainty evaluation of the determination of benzoic acid. Methods: The content of benzoic acid was determined by acid-base titration. By constructed mathematics model, the source of the measurement uncer-tainty was analyzed, and the uncertainty components were quantized and combined. Results:The expanded uncertainty of benzoic acid was 0. 36% and the results were expressed as(99. 99 ± 0. 36%,k=2). Conclusion:The mathematics model is reasonable and relia-ble,and can be used in the uncertainty evaluation of content measurement of benzoic acid.

Objective To explore the effect of seminar applied in instruction of Introduction of Nursing Science for advanced vocational nursing students.Methods A total of 246 advanced vocational nursing students admitted in 2013 from class 1 to class 5 were named as the control group,who received traditional teaching method.Meanwhile a total of 252 advanced vocational nursing students admitted in 2013 from class 6 to 10 were set as the experimental group,and were given seminar teaching.We adopted California Critical Thinking Dispositions Inventory Scale,Academic Self-efficacy Scale and an anonymous questionnaire for teaching satisfaction.Theoretical examination was used to be final evaluation.Results The scores of theoretical examination in the experimental group were higher than that of the control group.The scores of critical thinking ability and academic self-efficacy of the experimental group were higher than those of the control group,with a significant difference.The result of the anonymous questionnaire showed that the experimental group showed a higher satisfaction degree with seminar teaching method.Conclusions Seminar teaching method applied in Introduction of Nursing Science is feasible and effective,which is better than traditional method in improving critical thinking ability,academic self-efficacy and teaching satisfaction.

AIM:To analyze the clinical significance of axial length, diopter and retinal nerve fiber layer thickness in hyperopia children with anisometropia amblyopia. ·METHODS: From January 2015 to January 2017 in our hospital for treatment, 103 cases, all unilateral, were diagnosed as hyperopia anisometropia amblyopia. The eyes with amblyopia were as experimental group ( 103 eyes), another normal eye as control group (103 eyes). We took the detection with axial length, refraction, foveal thickness, corrected visual acuity, diopter and the average thickness of retinal nerve fiber layer. ·RESULTS: Differences in axial length and diopter and corrected visual acuity were statistically significant between the two groups (P<0. 05). The two groups had no significant difference in retinal nerve fiber layer thickness (P>0. 05). There was statistical significance difference on the foveal thickness (P<0. 05). There was a negative correction correlation between the visual acuity, axial length with foveal and peripapillary nerve fiber layer thickness, but no significant difference in correlation ( P>0. 05 ). The positive correlation between diopter with nerve fiber layer thickness of foveal and around the optic disc were no statistically significant difference (P>0. 05). ·CONCLUSION:Retinal thickness of the fovea in the eye with hyperopic anisometropia amblyopia were thicker than those in normal eyes;the nerve fiber layer of around the optic disc was not significantly different between the amblyopic eyes and contralateral eyes. The refraction and axial length had no significant correlation with optic nerve fiber layer and macular foveal thickness.

Acute pancreatitis has uncertain and complicated conditions,and non -surgical treatment is mainly used during the early stage. However,as for the causes of acute pancreatitis in early stage,timely surgical intervention should be given to control some causes.This arti-cle also elaborates on the application of percutaneous drainage and video -assisted minimally invasive surgery.It is pointed out that there are still controversies over the advantages and disadvantages of minimally invasive surgery and conventional laparotomy and how to select video -assisted minimally invasive surgery,and that in depth studies are still needed in future.

This article adopts an ecologistic perspective to analyze the regularity of psychological phenomena,examine the mechanisms of psychological problems and mental disorders,and discuss the process of psychological counseling and therapy.The author proposes that the practice of counseling and psychotherapy should be directed with an ecological view.A practitioner needs to not only focus on the problems and symptoms,but also consider the restoration and development of the personality foundation of the individuals who seek for help.A practitioner should not only pay attention to visitors'psychological defects,but also try to assist the development of their positive characters which could alleviate symptoms,and promote the construction of their outer environments that are beneficial for psychological rehabilitation.

Angle medicine is a concerted application of three kinds of Chinese materia medica for a certain cause, pathogenesis and disease. Professor HAN Fei is a famous TCM pediatric specialist. She has been working on children tic disorder for a number of years, with a lot of experience. This article introduced Professor HAN Fei's experience in treatment of children tic disorder by using angle medicine, and briefly analysed the reasons and connotation of application, including Margaritifera Concha combine with Dragons Bones and Ostreae Concha, Paeoniae Radix Alba combine with Bombyx Batryticatus and Cicadae Periostracum, Xanthii Fructus combine with Angelicae Dahuricae Radix and Magnoliae Flos, Polygoni Multiflori Caulis combine with Acori Tatarinowii Rhizoma and Albiziae Cortex.

OBJECTIVE:To systematically review the efficacy and safety of Ambrette capsule combined with Tripterygium gly-cosides tablet versus Tripterygium glycosides tablet alone in the treatment of diabetic nephropathy to provide evidence-based refer-ence for clinical treatment. METHODS:Retrieved from CJFD,Wanfang database,VIP database,Cochrane Library,EMBase and Medline randomized controlled trials(RCT)about Ambrette capsule combined with Tripterygium glycosides tablet(test group)ver-sus Tripterygium glycosides tablet alone(control group)in the treatment of diabetic nephropathy were collected. Meta-analysis was performed by using Rev Man 5.1 software after data extraction and quality evaluation. RESULTS:A total of 5 RCTs were includ-ed,involving 400 patients. Results of Meta-analysis showed the effective rate [OR=4.10,95%CI(2.27,7.38),P<0.001],24 h uri-nary protein quantificative value[MD=-0.54,95%CI(-0.72,-0.36),P<0.001] in test group were significantly higher than con-trol group,there were statistical significances. alanine aminotransferase value [MD=0.14,95%CI(-1.08,1.36),P=0.82] and changes value of peripheral white blood cells(WBC)[MD=-0.31,95%CI(-0.64,0.03),P=0.07] were not statistical difference between 2 groups. CONCLUSIONS:Efficacy of Ambrette capsule combined with Tripterygium glycosides tablet in the treatment of diabetic nephropathy were superior to Tripterygium glycosides tablet alone with similar safety. Due to limit of methodological quali-ty,more strict,long-term follow-up large-scale RCTs were required to validate the conclusion.

Objective To explore the effect of health failure mode and effects analysis(HFMEA)in reducing the risk of medication errors in of inpatients.Methods HFMEA was used to assess potential risk factors for medica-tion management process,in order to analyze the failure mode and the causes of potential risks.Effective precautionary measures were formulated and implemented.Results After the intervention.the incidence rate of errors in medication had been reduced from 5.21% to 1.77%,and the difference was statistically significant(χ2 =201.06,P <0.01). Conclusion HFMEA is effective in reducing the events of errors in medicine of inpatients.So as to guarantee the safety of the clinical medication of inpatients.

Invasion aud metastasis are the major biological characteristics of malignant tumors.The studies in past decades showed that lymphangiogenesis was closely related to cancer metastasis.The metastasis of tumor is a complex pathological process which involved in multiple genes and protein factors.This review discussed the structure and physiological characteristics of the lymphatic system,elaborated the factors in lymphangiogenesis,the relationship of metastasis and lymphangiogenesis,and major mechanism of tumor metastasis through lymphatic vessels.

Objective: To observe the clinical effect of heat-sensitive moxibustion on abdominal distension following laparoscopic cholecystectomy. ＜br> Methods: A total of 240 cases were randomly allocated into an observation group and a control group according to their admission sequence, 120 in each group. Cases in the observation group were treated with conventional care, glycerol enema and heat sensitive moxibustion, whereas cases in the control group were only treated with conventional care and glycerol enema. Then the passage of gas by anus within 24 h and improvement of abdominal distension were observed in both groups. ＜br> Results: There were statistical differences in the emergence time of bowel sounds and the initial passage of gas by anus between the two groups (bothP＜0.05). The therapeutic effect in the observation group was better than that in the control group (P＜0.05) . ＜br> Conclusion: Heat-sensitive moxibustion has reliable effect for abdominal distension following laparoscopic cholecystectomy.