Objective To explore the effect of seminar applied in instruction of Introduction of Nursing Science for advanced vocational nursing students.Methods A total of 246 advanced vocational nursing students admitted in 2013 from class 1 to class 5 were named as the control group,who received traditional teaching method.Meanwhile a total of 252 advanced vocational nursing students admitted in 2013 from class 6 to 10 were set as the experimental group,and were given seminar teaching.We adopted California Critical Thinking Dispositions Inventory Scale,Academic Self-efficacy Scale and an anonymous questionnaire for teaching satisfaction.Theoretical examination was used to be final evaluation.Results The scores of theoretical examination in the experimental group were higher than that of the control group.The scores of critical thinking ability and academic self-efficacy of the experimental group were higher than those of the control group,with a significant difference.The result of the anonymous questionnaire showed that the experimental group showed a higher satisfaction degree with seminar teaching method.Conclusions Seminar teaching method applied in Introduction of Nursing Science is feasible and effective,which is better than traditional method in improving critical thinking ability,academic self-efficacy and teaching satisfaction.

Objective:To establish a method for the uncertainty evaluation of the determination of benzoic acid. Methods: The content of benzoic acid was determined by acid-base titration. By constructed mathematics model, the source of the measurement uncer-tainty was analyzed, and the uncertainty components were quantized and combined. Results:The expanded uncertainty of benzoic acid was 0. 36% and the results were expressed as(99. 99 ± 0. 36%,k=2). Conclusion:The mathematics model is reasonable and relia-ble,and can be used in the uncertainty evaluation of content measurement of benzoic acid.

AIM:To analyze the clinical significance of axial length, diopter and retinal nerve fiber layer thickness in hyperopia children with anisometropia amblyopia. ·METHODS: From January 2015 to January 2017 in our hospital for treatment, 103 cases, all unilateral, were diagnosed as hyperopia anisometropia amblyopia. The eyes with amblyopia were as experimental group ( 103 eyes), another normal eye as control group (103 eyes). We took the detection with axial length, refraction, foveal thickness, corrected visual acuity, diopter and the average thickness of retinal nerve fiber layer. ·RESULTS: Differences in axial length and diopter and corrected visual acuity were statistically significant between the two groups (P<0. 05). The two groups had no significant difference in retinal nerve fiber layer thickness (P>0. 05). There was statistical significance difference on the foveal thickness (P<0. 05). There was a negative correction correlation between the visual acuity, axial length with foveal and peripapillary nerve fiber layer thickness, but no significant difference in correlation ( P>0. 05 ). The positive correlation between diopter with nerve fiber layer thickness of foveal and around the optic disc were no statistically significant difference (P>0. 05). ·CONCLUSION:Retinal thickness of the fovea in the eye with hyperopic anisometropia amblyopia were thicker than those in normal eyes;the nerve fiber layer of around the optic disc was not significantly different between the amblyopic eyes and contralateral eyes. The refraction and axial length had no significant correlation with optic nerve fiber layer and macular foveal thickness.

Objective:To establish an HPLC method for the determination of aspartame in Xiaoer Anfen Huang Namin granule. Methods:An Agilent Zorbax SB-C18 column(250 mm × 4. 6 mm,5 μm)was used with the mobile phase of acetonitrile-0. 05 mol·L -1 H3 PO4(20 ∶80). The flow rate was 1. 0 ml ·min -1 and the detection wavelength was 204 nm. The column temperature was 25℃ and the injection volume was 10 μl. Results:Aspartame had a good linear relationship within the range of 21. 72- 868. 67 μg · ml -1(r = 1. 000 0). The average recovery of aspartame was 99. 36% and RSD was 0. 3% (n = 6). Conclusion:The method has good stability and repeatability,and is suitable for the quality control of Xiaoer Anfen Huang Namin granule.

In the view of the ethics, this paper analyzed the present situation and problems of special physical education practitioners in China, and pointed out that the conflict of values, conflict of interests, job burnout, and educational value view were the practical ethical confusion that influenced special physical education practitioners. It put forward that ethical construction of special physical education practitioners should set up human-oriented concept, highlight the ethical feelings of humanism, formulate feasible and operable ethical norms for special physi-cal education work, improve practitioners′professional proficiency and ethical awareness, and establish the human-oriented humanistic care professional ethics idea.

As an important policy, the multiple-site physician practice system is expected to promote the flow of physicians and optimize the distribution of health resources, though it is difficult to enforce in practice. From the perspective of institutional change, the fundamental reason lies in path dependence existing in system, organization and mindset:First, the government regulation system has a strong inertia to restrict the flow of physicians, and the multiple-site physician practice lacks the unity of legitimacy and rationality. Secondly, fierce competition between hospitals and the distribution pattern of rights and responsibilities between hospital and physician cause the hospitals to oppose multiple-site physician practices. Third, the stability tendency in mind and the desires for profit restrain the flow of physicians. Therefore, the institutional change of the multiple-site physician practice requires improvements in three aspects:the innovation of government systems to unlock the multiple-site physician practice must be accelerated to realize the unity of legitimacy and rationality;a change is needed in the operation logic of hospitals to control the profit incentives and management of practices by contract;the thought-pattern of physicians must be changed to con-front the proper demand for interests and build innovative incentive mechanisms.

Attention deficit and hyperactivity disorders (ADHD),a neurodevelopmental disability with core symptoms of inattention,hyperactivity and impulsivity increases the risk of many cognitive problems.However,the brain structures and pathways involved in the interplays between the core symptoms,such as activity deficits,and cognitive impairments have remained unknown over the past decades.This article review the academic developments in recent years that elucidate the neural mechanisms involved in the sensorimotor-cognitive difficulties at systematic,circuitry,cellular,and molecular levels.The treatment potentials of physical activity enhancement were addressed,as a new alternative and supplementary therapeutic strategy for ADHD,based on our current understanding of the neurobiology of cognitive-sensorimotor interaction.

Objective To explore the effect of health failure mode and effects analysis(HFMEA)in reducing the risk of medication errors in of inpatients.Methods HFMEA was used to assess potential risk factors for medica-tion management process,in order to analyze the failure mode and the causes of potential risks.Effective precautionary measures were formulated and implemented.Results After the intervention.the incidence rate of errors in medication had been reduced from 5.21% to 1.77%,and the difference was statistically significant(χ2 =201.06,P <0.01). Conclusion HFMEA is effective in reducing the events of errors in medicine of inpatients.So as to guarantee the safety of the clinical medication of inpatients.

After a description of the development of massive MOOC in domestic biomedicine and its characteris-tics, the major advantages and disadvantages of MOOC were analyzed in aspects of its copyright , guiding role of teachers, course experiments, and independent study of students, the application of MOOC in medical libraries was elaborated with 4 suggestions put forward for the development of MOOC in medical libraries.

Objective To explore the value of fractional exhaled nitric oxide (FeNO) in diagnosis and treatment of asthma-COPD overlap syndrome (ACOS).Methods A total of 195 patients categorized into elderly ACOS,asthma,COPD and chronic cough groups were consecutively admitted from September 2013 to June 2014 in our hospital.All patients were examined with chest imaging,fractional exhaled nitric oxide (FeNO) test,and pulmonary function tests to analyze the differences in FeNO,FEV1/pred％ and FEV1/FVC among four groups,and to detect the relevance of FeNO to FEV1/pred％ and FEV1/FVC within each group.Results Both of the ACOS and asthma groups had higher FeNO values than the COPD and control groups [(30.9 ± 27.8,34.5 ± 29.4) vs.(17.3 ± 9.9,16.1 ± 8.6),P ＜ 0.05],while the values of FEV1/pred％ and FEV1/FVC in the ACOS and COPD groups were significantly lower than those in the other twogroups [FEV1/pred％,(52.9±8.4,53.5 ±9.6) vs.(81.1 ±5.9,85.7 ±7.1),allP＜0.05; FEV1/FVC,(51.9 ± 7.2,50.7 ± 7.1) vs.(79.2 ± 4.8,81.0 ± 5.9),all P ＜ 0.05].Although FeNO was directly related to FEV1/pred％ in the control group,there were no significant correlation between FeNO and FEV1/pred％ (or FEV1/FVC) in the other three groups [ACOS group,r =0.115,-0.007 (P =0.464,0.963) ; asthma group,r =0.038,0.045 (P =0.772,0.733) ; COPD group,r =0.097,0.010(P=0.498,0.944); control group,r =0.315,0.091 (P =0.045,0.571)].Conclusions The combination of FeNO and pulmonary function tests can facilitate the differential diagnosis of ACOS and other chronic obstructive airways disorders.For the elderly COPD patients with higher FeNO values,it should be noted whether they were complicated by ACOS or not.Furthermore,the inhalation of corticosteroid can be used to reduce the airway inflammation in these patients.