1.Effect of deproteinised calf blood extract on experimental gastric ulcer in rats
Ning CAI ; Hongxin WANG ; Shuyuan LI ; Fe YAN
Chinese Pharmacological Bulletin 2003;0(08):-
AIM To observe the effect of deprot einised calf blood extract(DCBE) on experimental gastric ulcer in rats. METHODS Ulcer model of SD rats induced by acetic acid, half male and female, were divided into three group s randomly, the control group and the two treatment group DCBE (30 mg?kg -1 or 60 mg?kg -1 ). Following the two and four weeks of experiment, the gastric acid degr ee, activity of pepsin, area of ulcer, the number of tela leukocyte and activity of myeloperoxidase (MPO) were observed. RESULTS Gastric acid deg ree and activity of pepsin showed no significant difference between treatment gr oup and control group, either in DCBE 30 mg?kg -1 or in 60 mg?kg -1 , but area of ulcer, the number of tela leukocyte and the activity of myeloperoxi dase (MPO) showed a significant difference between treatment group and control group and the e ffects of 60 mg?kg -1 group were significantly decreased as compared with that of 30 mg?kg -1 group. CONCLUSION DCBE can significantl y promote tissue healing of gastric ulcer induced by acetic acid in SD rats.
2.Treatment and prognosis of squamous cell carcinoma of thyroid.
Yaohong WU ; Chuanzheng SUN ; Yan XI ; Ruimei SUN ; Jimin FE ; Xiaojiang LI ; Jun SUI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2010;24(6):241-243
OBJECTIVE:
To investigate the treatment and prognosis of the patients with squamous cell carcinoma of thyroid.
METHOD:
The clinical data of all patients with squamous cell carcinoma of the thyroid in our hospital from Dec. 1994 to Dec. 2008 were analyzed retrospectively.
RESULT:
The overall 1-year, 3-year survival rates were 36.4% and 9.1% respectively. The median survival time was 8 months. Survival analysis showed the patients receiving surgery and postoperative radiotherapy had a better prognosis.
CONCLUSION
The prognosis of squamous cell carcinoma of thyroid was poor; the patients with squamous cell carcinoma of thyroid maybe get a better prognosis by receiving surgery and postoperative radiotherapy.
Adult
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Carcinoma, Squamous Cell
;
diagnosis
;
therapy
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Female
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Humans
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Male
;
Middle Aged
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Prognosis
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Retrospective Studies
;
Thyroid Neoplasms
;
diagnosis
;
therapy