1.Mechanism and Therapy on Phlegm and Static Blood Syndrome of Migraine
Yupeng DI ; Fawei WANG ;
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(02):-
Because of the effects of misbalance of Qi/Blood and Yin/Yang and abuse of medicine,food and emotion,phlegm and static blood syndrome is easy to be made in the course of pathological changes of migraine.Phlegm and static blood syndrome is the important factor in the occurrence and development of migraine. In the whole period of migraine it is showing not only stabbing pain immovable for a long time,but also showing languor and scarce of appetite;The method of dissipating blood stasis and phlegm should be used effectively.
2.Observation of effects of tiaozhi zengshou tang on regulation of dyslipidemia
Zhikuan WANG ; Fawei WANG ; Guangyi WANG
Chinese Journal of Tissue Engineering Research 2005;9(43):183-185
BACKGROUND: Dyslipidemia is the important risk of cardiac cerebral vascular diseases, such as arthrosclerosis and coronary heart disease, etc.OBJECTIVE: To observe the clinical therapeutic effects of tiaozhi zengshou tang (herbal decoction) on intervention of dyslipidemia.DESIGN: Randomized, group controlled observation.SETTING: Department of Oncology, Department of Chinese Medicine and Department of Cardiology of General Hospital of Chinese PLA.PARTICIPANTS: Totally 120 cases from inpatients with dyslipidemia in Department of Chinese Medicine and Department of Cardiology of General Hospital of Chinese PLA and outpatients in Clinic of Blood lipid from February 2002 to January 2004.METHODS: Totally 120 cases of dyslipidemia were randomized into 3 groups. In Chinese herb group (43 cases), tiaozhi zengshou tang (herbal decoction) was prescribed, one dose/d, taking separately before breakfast and dinner. In western drug group (40 cases), pravastatin sodium was prescribed, 10 mg/tablet, 1 tablet/d, taking orally before sleep at night. Integrative group (37 cases) both pravastatin sodium and herbal decoction were prescribed, the dosage, composition and administration were same as previous. The treatment lasted 8 weeks, and then, the therapeutic effects on changes of blood lipid and harmful effects were observed.MAIN OUTCOME MEASURES: Comparisons of therapeutic effects and harmful effects among groups.RESULTS: 120 cases were employed in the experiment, but 27 of those were dropped out due to loss of contact and absent re-visiting in time. Total parison of therapeutic effects among groups: The effective rates in Chinese herb group and western drug group were similar (81%, 80%, P > 0.05),changes of blood lipid series before and after treatment in each group: In Chinese herb group, triglyceride (TG) (2.59t1.64) mmol/L was reduced to (1.56±0.72) mmol/L, serum total cholesterol (TC) (5.30±1.71) mmol/L was reduced to (4.35±0.85) mmol/L (P < 0.01) and HDL-Cholesterol (HDL-Ch)(1.32±0.37) mmol/L was increased to (1.50±0.22) mmol/L (P < 0.05). In western drug group, TG (2.84±1.50) mmol/L was reduced to (2.04±0.98) mmol/L,serum TC (5.50±1.22) mmol/L was reduced to (4.71±0.89) mmol/L (P < 0.05,P < 0.01) and APoA1 (1.24±0.21) g/L was increased to (1.49±0.15) g/L (P < 0.01). In integrative group, the therapeutic effects were significant in re ducing TG, TC, LDL-Ch and APoB and increasing APoA1 and HDL-Ch harmful effects in Chinese herb group were less than western drug group (1 case, 7 cases).CONCLUSION: Tiaozhi zengshou tang provides definitely clinical therapeutic effects in dyslipidemia and presents low incident of harmful effects.
3.Characteristic and Medication Principle of Traditional Chinese Medicine on Senile Diseases
Fawei WANG ; Aizhen HAO ; Zhikuan WANG ;
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(04):-
Objective: In order to have more direction to treat senile diseases,the feature of diseases and the principle of medication are investigated.Methods: Through combining the experiences of prevention and cure of senile diseases,we can conclude and analyze from its characteristics of imbalance of YIN and YANG,clumsy of reaction,deterioration of entrails,inclusion of excess and deficiency et al.Results: Aiming its physiological and pathological feature,we propose the standpoint that we should limit reinforcing and reducing,protect gastric-qi and prescribe containing minerals.Conclusion: It has evident specificity when we diagnose and prescribe for the aged,and can not equate that to the young.
4.Effect of Shuyusan on Behavior and Concentrations of Neurotransmitters in Chronic Stress Depression Rats
Liping CHEN ; Fawei WANG ; Dongmei DUAN
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(05):-
Objective To investigate the effect of Shuyusan on the behavior of chronic stress induced depression model rats, as well as concentrations changes of norepinephrine (NE), dopamine (DA) and serotonin (5-HT) in cerebral cortex. Method Fifty mice were randomly divided into 5 groups:normal control group, model group, amitriptyline group, and high/low dose prescription group of Shuyusan. Except normal group, the other groups were given the chronic mild unpredicted stress for 21 days. After 21 days different stimulation, open-Field test was used to estimate the behavior of rats, the concentrations of NE, DA and 5-HT were detected with fluorescence spectrometer method. Results Horizontal and vertical motion of the model group was significantly lower than that of the control group (P
5.Effects of Shenlong decoction on life quality of the aged patients with cerebral vascular dementia
Liping CHEN ; Fawei WANG ; Jianjun JIA ;
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
Objective To investigate the clinical effects of Shenlong decoction(main ingredients consisted of ginsent root,radix polygonimultiflori,Pheretima,Ligusticum wallichii,Fructas Alpiniae oryphyllee etc.)on the treatment of cerebral vascular dementia (VD)in the elderly patients.Methods VD in all the patients(age:72.1?5.3 years old)was diagnosed according to the APA criteria, and the cerebrovascular diseases were confirmed by CT or MRI.68 patients were divided into 2 groups randomly.The experimental group consisting of 36 patients was given Chinese traditional medicine,Shenlong decoction,orally 500ml q.i.d.for 3 months,and the other 32 patients were given acetamide pyrrolidone(piracetam)orally 1.6g,tid for 3 months as a control group.The MMSE(Mini Mental State Examination)and BBS(Bless Behaviour Schedule)were used to evaluate the cognitive function and the daily activity in those patients be- fore and after treatment.Results After treatment,the scores of cognition and daily activity were improved in all the patients with VD. The effective rate in the Shenlong group was 52.8%,and 53.13% in the piracetam group.There was no significant difference in the im- provement of the short time memory and orientation ability between the two groups.However,compared with the control group,the score of daily activity was significantly improved in the Shenlong decoction group only(P
6.Protectively Eeffect Study of Yixintang on Injury of Myocardial Ischemia-Reperfusion
Liping CHEN ; Fawei WANG ; Jun YI
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(02):-
Objective To observe the protective effect of Yixintang on injury of myocardial ischemia-reperfusion with isolated working heart. Method 40 mice are randomly divided into 5 groups:control group, Yixintang group 1, Yixintang group 2, Yixintang group 3 and Verapamil group. The change of left ventricular systolic output pressure (LVSP), rate of rise left ventricular pressure (?dp/dtmax), left ventricular end diastolic pressure (LVEDP), heart rate, as well as the contain of malondialdehyde (MDA) release and activity of superoxide dismutase (SOD) were measured as investigate indicator. Results After ischemia and reperfusion in Yixintang group, the heart can be good recovery its function. The values of myocardial dynamics and hemodynamics indexes LVSP and ?dp/dtmax, in Yixintang group 3 and Verapamil group the indicator were obviously higher than those in the control group, after ischemial and reperfusion. The content of MDA in myocardial tissue in Yixintang group 3 and Verapamil group after ischemia and reperfusion was obviously lower than in other groups. It also could depress the activity of SOD, there was significant difference among Yixintang group 3, Verapamil group and control groups (P
7.Observation on subglossal collateral vessels in elderly patients with diabetes
Aizhen HAO ; Yi LIU ; Fawei WANG
Medical Journal of Chinese People's Liberation Army 2001;0(09):-
Objective To observe the changes in sublingual collateral vessels of elderly patients with diabetes. Methods Sublingual collateral vessels of 88 patients with diabetes were observed and compared with that of 76 normal people. Results The changes in sublingual collateral vessels of patients with diabetes were more serious than that of normal people (u=4.174, P
8.TCM Methods to Treat Diabetes Complicated with Respiratory Tract Infection among Elderly Patients
Aizhen HAO ; Fawei WANG ; Yupeng DI
Chinese Journal of Nosocomiology 2006;0(05):-
OBJECTIVE To investigate the mechanism and treatment of diabetes among elderly patients from the view of traditional Chinese medicine(TCM).METHODS On the basis of clinical experience and the achievement of the modern medicine,we expounded the mechanism of diabetes among elderly patients and treat from eight parts.RESULTS Using eight different TCM methods to treat diabetes elderly patients,we found their good curative effect with less adverse reaction,good prognosis,and very suit for old man.CONCLUSIONS TCM has large potentiality and advantage among diabetes elderly patients complicated with respiratory tract infection.
9.Qingfei Decoction in Acute Upper Respiratory Tract Infections:A Clinical Investigation
Liping CHEN ; Xiaoping TANG ; Fawei WANG
Chinese Journal of Nosocomiology 2006;0(08):-
OBJECTIVE To investigate the effect of the Qingfei decoction in the acute upper respiratory tract infections.METHODS From Jan 2004 to Sep 2006,there were 68 cases with acute upper respiratory tract infections treated with chinese medicines.The patients were divided into 2 groups:36 cases were treated with Qingfei decoction,32 cases were treated with Shuanghuanglian granules as a control.Both of the groups were treated for 5 days,the clinical symptoms such as: fever,cough and sore throat were used to evaluate the efficacy of both groups.RESULTS Both of the groups were effective;the effective rate was 88.9% and 75.0% in the Qingfei group and in the control group,respectively.There was significant difference between 2 groups(P
10.Combined traditional Chinese and western medicine for treatment of ulcerative colitis: a report of 65 cases
Liping CHEN ; Fawei WANG ; Ping LIU
Medical Journal of Chinese People's Liberation Army 2001;0(07):-
Objective To evaluate the treatment of ulcerative colitis with combined Chinese oral herbs and herbs enema with western medicine. Methods 105 patients with ulcerative colitis diagnosed by colonoscopy were randomly divided into two groups: traditional combining with western medicine treatment group (treatment group) with 65 patients, and western medicine treatment group (control group) with 40 patients. In the treatment group the treatment consisted of oral herbs and enema herbs as well as sulfasalazine, while in the control group the patients received sulfasalazine only. After two courses of treatment, the immediate cure rate and cure rate after 2 years were assessed. Results The immediate cure rate and total efficacious rate of treatment group were 52% and 94.64% respectively, while those of control group were 36.2% and 82.5%, respectively. There was significant difference between two groups in the effective rate (P