1.Malignant Melanoma of the Foot in Patients with Diabetes Mellitus – A Trap for the Unwary
Paisal Hussin ; Seng Cheong Loke ; Fatimah Mohd Noor ; Maliza Mawardi ; Vivek Ajit Singh
The Medical Journal of Malaysia 2012;67(4):422-423
Melanomas on the foot are difficult to differentiate from
diabetic foot ulcers (DFU). In particular, acral lentiginous and amelanotic melanomas have a high chance of being misdiagnosed. We present two patients with diabetes
mellitus and malignant melanomas of the foot initially
diagnosed as DFU. Both cases were treated with wide
excision amputation and local dissection, without adjuvant
chemotherapy or radiotherapy. Both patients remain
disease-free up to the last follow-up visit. It is important to maintain a high index of suspicion and a skin biopsy should be done in any DFU with atypical features.
2.An Unusual Presentation of Neurotized Congenital Giant Melanocytic Nevus and Type 1 Neurofibromatosis: A Diagnostic Challenge
Qin Jian Low ; Tzyy Huei Lim ; Ri An Lee ; Seng Wee Cheo ; Noor &lsquo ; Ain Mohd Nasir ; Ikmal Hisyam Bakrin ; Wen Yee Evelyn Yap
Malaysian Journal of Medicine and Health Sciences 2022;18(No.1):372-374
Among the three subtypes of neurofibromatosis are type 1 and 2 neurofibromatosis and schwannomatosis, von
Recklinghausen disease also known as type 1 neurofibromatosis has an autosomal dominant inheritance. It is the
commonest form as and presents with numerous café-au-lait macules and neurofibromas. Giant congenital melanocytic nevus (CGMN) on the other hand is characterized by a melanocytic proliferation that present at birth. CGMN
develops due to a defective embryonic pigment cell (melanocyte) precursors development and are often present at
birth. Giant congenital melanocytic nevus (CGMN) and type 1 neurofibromatosis may occur together rarely. Clinicians should be aware of the rare presentation of both CGMN and type 1 neurofibromatosis in a patient.
3.Malnutrition and its associated factors among children under 5 years old in Putrajaya: a study protocol
Mohamad Hasnan Ahmad ; Nor Azian Mohd Zaki ; Fatimah Othman ; Azli Baharudin ; Ruhaya Salleh ; Cheong Siew Man ; Adibah Huda Mohd Zainul Arifien ; Nurin Iman Ahmad Kamal ; Noor Ani Ahmad ; Hazizi Abu Saad ; Poh Bee Koon ; Mohd Azahadi Omar ; Tahir Aris
Malaysian Journal of Nutrition 2021;27(No.1):141-151
Introduction: Prevalence of malnourished children in Putrajaya was unexpectedly
high in 2016. This paper describes the study protocol for a case-control study
conducted to identify the associated factors of malnutrition among children under
5 years old in Putrajaya. Methods: This study involved two phases. Phase I
was ‘screening’ where all children aged 6-59 months in 118 preschools and four
government health clinics were measured for their weight and height. The World
Health Organization Anthro software was used to determine the nutritional status
of these children. Phase II was the ‘interview’ where children from screening were
sampled into four pairs of case and control. The optimum sample size for the case
of stunted, wasted, underweight, and overweight were 380, 335, 318, and 308,
respectively. The same number of controls were recruited. Parents/caregivers of
selected children were approached to obtain data on parental factors, children factors,
food intake factors, and environmental factors that contributed to malnutrition.
Data analysis was performed by multiple logistic regression in SPSS version 26.
Results: Screening phase successfully measured 8,261 (50.1%) children from an
estimated 16,500 children under 5 years old in Putrajaya. The number of children
who were stunted, wasted, underweight, and overweight were 2,105 (25.5%), 512
(6.2%), 1,516 (18.4%), and 248 (3.0%), respectively. As overweight was undersampled, the number of controls for overweight was doubled to increase the power
of the study. Parents/caregivers of selected cases and controls were interviewed in
their household or any other venues at their convenience. Conclusion: This protocol
promises beneficial outputs to stakeholders and policy makers that can be used for
combating malnutrition in children.