This paper was to discuss the case analysis method for teaching basic theory of TCM. First, it is found that case analysis can help improve learning interest of students and develop their abilities of thinking and analysis. Secondly, it can play a solid foundation for students to study the following professional basic courses and help them gain the interest of other courses, and understand the continuous knowledge of TCM. Finally, it benefited teachers to develop their ability of teaching and clinical practice.

The physical feature of gallbladder is gallbladder qi dominating ascending, which has two meanings, one is gallbladder dominates ascending of Yang qi, and the other is gallbladder has the nature of dispersing stagnated qi.Gallbladder has the physical features of gallbladder qi dominating ascending and bile dominating decending. The opposite movement of ascending and descending conforms to Yin and Yang theory in Chinese medicine.

Objective: To analysis the finding of never conduction velocity(NCV) in patients with ALS and investigate the clinical significance of NCV. Methods: Keypoint was applied to estimate the NCV of median,ulnar,tibial,peroneal in 106patients with ALS and 123healthy volunteers,in which sunface electrodes was used for both stimulating and recording. Results: SCV of median and MCV of median,ulnar,peroneal in patient group was a significant difference as compared with the normal subjects;A significant difference was noted in all latency except sensory fiber of median.A significant differencence of compound muscle action potential amplitude of medial,ulnar,tibial was noted in two groups. Conclusion: NCV in patients with ALS could show abnormal slowing,so the valuation for differentiation of NCV is not so good as the clinical signs and the distribution of electromyographic abnormalities.

Military medical ethics is a famous theory abroad and have drawn controversy.We should enhance the study of the subject.Understanding the principle and the difficulties is the premise for the study of the theory.

This article introduced the recognitions of the ovigin and development of phlegm and fluid-retention by ancient Chinese and Japanese doctors,as well as the formation of phlegm,the idenfification,and the treatment based on syndrome differentiation.Chinese and Japanese doctors enriched the understanding of phlegm together with the therapeutic methods.

Medical insurance system is good for fair distribution and disposition, dealing with relationships between social benefits and economic benefit, as well as fair implementation on both doctors and patients' intersets, so that it benefits medical moral fairness.

BACKGROUND: Effect of metabolic disorders after kidney transplantation on prognosis, especially new-onset diabetes after transplantation (NODAT), has aroused concerns. OBJECTIVE: To investigate the risk factors for NODAT in renal transplant recipients, thus providing reference for identifying high-risk patients and taking active prevention measures. METHODS: Clinical data of 365 patients undergoing allograft renal transplantation were analyzed retrospectively. According to whether NODAT occurred or not, all the patients were assigned to NODAT (n=71) and non-NODAT (n=294) groups. The independent risk factors for NODAT were determined using univariate and non-conditional multivariate logistic regression analysis. RESULTS AND CONCLUSION: The cumulative incidence of NODAT in renal transplant recipients within year postoperatively was 19.45%. Non-conditional multivariate logistic regression analysis showed that age ≥ 45 years old, body mass index ≥ 25 kg/m2, family history of diabetes mellitus and acute rejection were associated with NODAT in renal transplant recipients. To conclude, the age, family history of diabetes mellitus, high body mass index and acute rejection can increase the incidence of NODAT in renal transplant recipients.

Idiopathic Refractory Nephrotic Syndrome (IRNS) has been an intractable problem in clinical treatment .Anti CD20 monoclonal antibody is a new type of immunosuppressive agent , which can induce the lysis and apoptosis of B cells .Significant-ly, it improves the prognosis of IRNS patients .In recent years, a number of case studies and clinical trials have been conducted on the effectiveness of anti CD20 monoclonal antibody in the treatment of children with IRNS .In this paper, the mechanism, clinical applica-tion, adverse effects and problems in the study of anti CD 20 monoclonal antibody in IRNS will be reviewed .

Objective To study the effects of ?-tocopheryl succinate (?-TOS) on apoptosis of gastric cancer cells induced by TRAIL. Methods The cell cycles and the percentage of apoptosis were analyzed with flow cytometer and the expressions of NF-?B, survivin, bcl-2 and caspase-3 in gastric cancer cells were assessed with Western blot. Results After being exposed to TRAIL 300ng/ml for 24 hours, the apoptosis rate was 36.05% for MKN28 and 11.80% for SGC-7901. When exposed to ?-TOS at 60?mol/L for 24 hours, the apoptosis rate was 9.0% for MKN28 and 8.5% for SGC-7901. With a combination of ?-TOS 60?mol/L and TRAIL 300ng/ml for 24 hours, the apoptosis rate was elevated to 48.1% for SGC-7901 and 63.7% in MKN28, respectively. The results of Western blot showed that TRAIL inhibited the expressions of NF-?B and survivin, while had no inhibition on the expressions of bcl-2 of SGC-7901 and MKN28 cell lines. The expression levels of bcl-2 and survivin had no change when the cells were exposed to ?-TOS alone. When the cells were treated with ?-TOS and TRAIL simultaneously, the expressions of NF-?B, bcl-2, and survivin were greatly decreased. Conclusions ?-TOS can enhance the activity of TRAIL in inducing apoptosis, and the down-regulation of the expression of NF-?B, bcl-2 and survivin may be involved in the mechanisms.

Objective: To investigate the antagonistic effect of lithium on the neurotoxicity of lead acetate and the possible mechanisms. Method: Wistar rats were randomly divided into control group, Pb group and four Pb+ LiCl groups fed with feed containing 3, 30, 300, 3 000 mg/kg LiCl respectively. All Pb exposed groups were given distilled water containing 0.2% PbAc. The changes of nNOS protein and gene expression in rats hippocampus were studied by ABC immunohistochemistry and the semiquantitative reverse transcription-polymerase chain reaction (RT-PCR) method. Rusults: Compared with the control group, the number of nNOS positive neurons in CA1 area and the nNOS mRNA content of hippocampus of LiCl (3, 30 mg/kg) groups were increased,while those of Pb-exposed rats were significantly decreased. Compared with Pb groups, the number of nNOS positive neurons and the nNOS mRNA content of Pb+LiCl (3,30,300 mg/kg) groups were increased. In dentate gyrus, the changes of the number of nNOS positive neurons coincided with the changes in CA1 area, but those in CA3 area showed little difference. Conclusion: Low dose of lithium could resist the lead neurotoxcity obviously.