Thirty five samples of cows sera were assayed for human HBV serological marker with ELISA method. Sixteen samples were HBsAg and/or HBeAg positive,of which human HBV-like particles were found in 6 samples by immuno electron microscopic procedure. There were 1-3 precipitation lines between 5 concentrated samples and horse anti-HBs sera one of which fused with that of human HBsAg. In all the samples human sera polyalbumin receptor (PHSAR) was negative with ELISA method, and 32P-HBV DNA dot hibridization was also negative.

Renal interstitial fibrosis represents the final common pathway of all chronic disease.The mechanism of renal interstitial fibrosis is very complex.It is not entirely clear now.The study found that epithelial-to-mesenchymal transition plays an important role in the renal interstitial fibrosis.Inhibition of epithelial-tomesenchymal transition may help to slow down the development and progression of renal interstitial fibrosis.The article mainly reviews the mechanism and treatment of epithelial-to-mesenchymal transition.

Objective To explore the synchronous cosmetic surgical procedures for the beauty-seekers who have both single eyelid and commonly horizontal cockeye in order to acheive either time saving or beautifying. Methods Firstly, the distance of moving backwards and shortening length of the eye muscle were calculated and designed according to the degree of cockeye; secondly, the height of the double eyelids line and positioning were re-designed; then the moving backwards and shortening of the horizontal macula were put up to rectify the cockeye; finally, the incisal double eyelid operation was performed. Results All 25 patients with inner cockeyes were corrected at the right position; 4 of 11 patients with outer cockeyes were corrected 5～10 degrees over the right position, and others were at the right position. The single eyelid with thin-eyelid and middle-thick-eyelid restored within 3 months; but the patient with thick-eyelid restored slowly, about half a year in average. 2 patients with redundant skin at inner corner of eye were also corrected at the right position. Conclusions Although there is somewhat difficulty in the plastic surgery for patients with cockeye and single eyelids, synchronous operation can save time and outlay, and also acheive the aim of beautifying. Therefore, it is a good approach to deal with cockeye.

Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Otorhinolaryngologic Surgical Procedures ; adverse effects ; methods ; Postoperative Complications ; prevention & control ; Sleep Apnea, Obstructive ; surgery ; Treatment Outcome ; Uvula ; surgery ; Young Adult

Adhesives ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Endoscopy ; Epistaxis ; therapy ; Female ; Humans ; Male ; Middle Aged ; Treatment Outcome ; Young Adult

Objective To investigate the distribution of authors,funding,institutions and regions of Chinese Journal of Orthopaedics between 2010 and 2015,understand the types and characteristics of authors＇ cooperation,identify the core author,core institutions and core regions,as well as evaluate academic level and journal quality from the view of literature citation.Methods According to Chinese Science Citation Database (referred CSCD) and bibliometric methods,we made statistical analysis,including the number of papers,cooperation,core authors,regional distribution of authors,systematic distribution of authors,productive institutions,funding sources and distribution.On the basis of Chinese science and technology journal citation reports (Compendex) from 2013 to 2015,the main indicators and coupling relationship of bone surgery journals were evaluated.Results From 2010 to 2015,Chinese Journal of Orthopaedics published 1 342 papers.There were 1 009 first authors,among which 802 authors (79.48％,802/1 009) published only one paper; 1 293 co-author papers contributed to 96.35％ cooperation rate and 5.69 degree of cooperation.Forty-nine papers (3.65％,49/1 342) had only one author,and 799 papers (59.54％,799/1 342) were published by affiliated Hospital,321 papers (23.92％,321/1 342) by provincial and municipal hospitals,138 papers (10.28％,138/1 342) by military hospital.There were 63 (6.24％,63/1 009) core authors publishing 252 papers (18.78％,252/1 342),and 20 productive institution publishing 630 papers (46.94％,630/1 342) in which Beijing was ranked at No.1 with 238 papers (17.73％,238/1 342).From 2010 to 2015,Chinese Journal of Orthopaedics publishing papers got 652 funding.From 2012 to 2014,its core total citations were 10 153,ranked No.1 in bone surgery journals in 2012 and ranked No.2 in 2013-2014; impact factors rose from ranked No.4 in 2012 to ranked No.2 in 2014,and the comprehensive evaluation of total score ranked No.1 in 2012-2014.Conclusion Chinese Journal of Orthopaedics has a strong team with a large number of authors,extensive source of institutions,a wide regional distribution,high cooperation rate,and strong ability to attract assistance funded paper.Affiliated Hospital and provincial and municipal hospitals are the main source of paper in the journal.Its core total citations,impact factor,subject diffusion index,academic impact indicators,comprehensive evaluation score were located in front rank of the same field of journals.

0.05).Both SBP and DBP were declined significantly in both two groups(P0.05).Heart rate decreased from (81?9)b/min to (68?7)b/min in bisorpolol group.But there wasn't this effect in contrast group.It was superior to that of contrast group significantly too(P

OBJECTIVE:To evaluate the influence of different process technics on the contents of catalpol in rehmannia root.METHODS:Dual wavelength TLC-scanning method was used to determine the contents of catalpol in different processed products of rehmannia root.RESULTS:There were significant differences in the contents of catalpol in the different processed products of rehmannia root and the crude herb.CONCLUSION:The contents of catalpol will be changed after processing with different processed methods and adding different supplementary materials.

OBJECTIVE:To study the current situation of development in personnel resources of licensed pharmacists of drug supply enterprises in China and the ways of development.METHODS:The existing problems in the development of per-sonnel resources of licensed pharmacists were analyzed through the ways of questionnaires and interviews.RESULTS&CONCLUSIONS:The drug supply enterprises lacked collocation and application rules of pharmacists and there lacked a system for employing,training,assessing and encouraging the licensed pharmacists.Furthermore,because of the inefficient policy,the supply-demand market of licensed pharmacists was unsatisfactory and the functions of the pharmacists were incomplete.Therefore,the practicing environment for the licensed pharmacists must be optimized.It is recommended that a perfect system of employment and assessment should be established;the full-time practice and the part-time practice should be allowed to coexist;the information network platform for supply-demand of the licensed pharmacists should be set up to improve the management as well as self-discipline function of licensed pharmacist association,better the further education system,and therefore promote the development of personnel resoures.

Objective To observe the clinical effect of hyaluronic acid on conception rate of ectopic pregnancy patients who received conservative tubal operation under laparoscopy.Methods 100 patients with ectopic pregnancy received conservative tubal operation under laparoscopy treatment were selected.Hyaluronic acid was used in 50 cases (the treatment group),unused anti blocking preparations for the control group in 50 cases.Then patients were followed up on the tubal patency,and observed pregnancy after 1 year.Results The rate of tubal patency after menstrual clean was 84％ in the treatment group,which was significantly higher than 60％ in the control group(x2 =7.155,P ＜ 0.05).In the treatment group,40 cases were intrauterine pregnancy,4 cases were ectopic pregnancy,6 cases were infertility.The rate of intrauterine pregnancy after 1 year was 80％ in the treatment group,which was significantly higher than 56％ in the control group(x2 =6.65,P ＜ 0.05).Conclusion Hyaluronic acid is effective in preventing tubal adhesion in the ectopic pregnancy patients who received laparoscopic conservative surgery,and can improve the postoperative tubal patency rate and conception rate.