Abdominal aortic aneurysm (AAA) is a common aortic disease causing death. Many factors are associated with AAA rupture, such as aneurysm diameter, shape, intraluminal thrombus, and hemodynamic changes. It has been shown that hemodynamic changes may be one of the main risk factors for AAA rupture. There are several imaging modalities to evaluate AAA, in which Doppler ultrasound and magnetic resonance blood flow imaging are capable of assessing the hemodynamic changes in AAA. This review will discuss the risk factors for rupture and imaging advancement of AAA.

OBJECTIVE: To discuss the strategy of comparative advertisement use in medical profession. METHODS: The excellence and the shortcoming of comparative advertisement were analyzed in case study, and the strategy of comparative advertisement use in medical profession was put forward. RESULTS&CONCLUSIONS: The use of comparative advertisement in a practical, rational and innovative way helps advertisement to play its potentials.

BACKGROUND:Silk fibroin has excel ent biocompatibility, biodegradability and unique mechanical properties. Its composite, silk fibroin/nano-hydroxyapatite, can simulate the composition and structure of nature bone tissue, contributing to remedying the insufficient mechanical properties of nano-hydroxyapatites. OBJECTIVE:To observe the biological safety of silk fibroin/nano-hydroxyapatite composites. METHODS:Silk fibroin/nano-hydroxyapetite composite biomaterial was synthesized by the coprecipitation method using silk fibroin, calcium chloride and diammonium phosphate as raw materials. According to the demands of International Standard Organization (ISO10993) and Technical Evaluation Standards of Biomedical Materials and Medical Instruments promulgated by Chinese Board of Health (GB/T 16886), experiments of cel toxicity in vitro, acute toxicity and hemolysis were investigated to evaluate the biocompatibility of silk fibroin/nano-hydroxyapetite composite. RESULTS AND CONCLUSION:L929 cel s co-cultured with silk fibroin/nano-hydroxyapatite composite leaching liquor had good cel morphology, metabolism and proliferation. The leaching extract of silk fibroin/nano-hydroxyapatite composite injected into mice intraperitoneal y had no significant adverse reactions. And silk fibroin/nano-hydroxyapatite composite extracts caused 2.39%blood hemolysis, less than the international standards 5%. These experimental results on cel toxicity test in vitro, acute toxicity and hemolysis met the demands of ISO10993 and GB/T, which show the biological safety of the silk fibroin/nano-hydroxyapatite composite for clinical application.

ObjectiveTo investigate the value of hysterosalpingography in the diagnosis of infertility.MethodsHysterosalpingographic and clinical materials of 1 320 cases with infertility were collected and analyzed retrospectively. ResultsAmong 1 320 cases, the percentage of abnormal uterus was 9.55 ％. Bilateral patency of fallopian tubes cases were accounted for 46.67％, and bilateral obstruction and unilateral obstruction were accounted for 27. 05％ and 26.29％ respectively. The obstruction position of the interstitial portion, the isthmus, the ampulla, the complete fimbrial and the part fimbrial were 23.94％, 16.21％ ,6.13％ ,23.09％ ,30. 63％ respectively. The accidence of tubal obstruction in the secondary infertility group was significantly higher than that in the primary group (P ＜0.01 ) ,and in the secondary infertility group,the bilatral tubal obstruction frequencies for “abortion times ≥3”were significantly higher than those for “abortion times ＜ 3” ( P ＜ 0.01 ). The pregnancy rate was 27.65％ in three months after hysterosalpingography. ConclusionHysterosalpingography was a cost-effective and indispensable method for diagnosing female infertility.

Liver transplantation has been taken as one of the most effective therapies for patients with end-stage liver disease. However, 10%-40% patients develop biliary complications (BC) after transplantation and 6%-13% patients have to receive liver retransplantation,with the mortality being around 19%. BC is one of the major risk factors for the prognosis of liver transplantation. This review summarizes the etiology and the mechanism(s) of biliary complications after liver transplantation.

Objective To study the repairment of pancreas mesenchymal stem cells(MSCs) on injured pancreas of rats,and find a new source of cells for treatment of diabetes. Methods ① Pancreases were taken out of three-day-old Wistar rats under bioclean condition,and cells were obtained by V-collagenase digestion. Generations were passed by conventional culture,cells were purified by adherence screening method,cell morphous was observed by Giemsa staining. The expressions of surface marker CD34 and CD44 were determined by FCM,and compared with bone marrow MSCs(BM-MSCs),the differences in character and function were observed. ②The experimental rats were divided into two groups randomly. Pancreas ischemic necrosis model was made by deligation,then the purified pancreas MSCs were marked with DAPI and then were transplantated partially. After two weeks,the survival rate was measured and histopathological detection was performed. Results ① The cells had concordant morphous gradually with vigorous generation. There was no significant difference in morphology and surface antigen compared with BM-MSCs.② The survival rate in experimental group was 75% ,the necrotic tissue had basi-rebounded. Blue fluorescent was observed in repaired pancreas tissues. The survival rate in control group was 20%. The survival rate in experimental group was higher than that in control group (P

Objective A classification for hepatic venous outflow obstruction after piggyback liver transplantation (PBLT) and its clinical significance.Methods We conducted a retrospective study on 248 patients who underwent liver transplantation from May 2000 to August 2006.The aims were to elucidate the causes and treatment of postoperative venous outflow obstruction.Results Venous outflow obstruction occurred in 38 patients after transplantation.Among those,2 (5.26％) had superior hepatic inferior vena cava (IVC) stenosis,13 (34,21％) had the hepatic vein anastomosis twisted at an angle,7 (18.42％) had IVC stenosis at the posthepatic segment,and 16 (42.10％) had outflow obstruction at the hepatic veins.In these 38 patients,34 underwent PBLT,2 underwent APBLT,and 2 COLT.Most patients with hepatic venous outflow obstruction improved with surgical treatment and interventional therapy.Conclusions Hepatic vein outflow obstruction was associated with the technique of hepatic vein anastomosis,the type of cavocaval anastomosis and graft size mismatch between the donor and the recipient.Performing piggyback liver transplantation according to the classification of hepatic vein and appropriate treatments could improve the prognosis of venous outflow obstruction in clinical practice.

Objective To observe the clinical characteristic and prognostic analysis of severe anti-N-methyl-D-aspartate receptor ( anti-NMDAR) encephalitis.Methods The clinical data of 9 patients with severe anti-NMDAR encephalitis were retrospective analyzed.Results Nine patients ( two male and seven females ) were taken care at ICU.They were 27.7 years old at average.The median course was 22.4 d and median length of stay in ICU was 50. 9 d.The mainly clinical characteristics were fever(7 cases), psychiatric behavioral symptoms(9 cases), seizures(9 cases) , decreased consciousness ( 8 cases ) , abnormal movement ( 7 cases ) , automatic instability ( 9 cases ) and hypoventilation(6 cases) .Three cases had ovarian teratoma.Anti-NMDAR antibodies in CSF of all patients were testing positive, while in serum were 6 cases.CSF-IgA in 7 cases were increased.The brain MRI indicated abnormal signals in temporal lobe, hippocampus in 3 patients.The EEG showed slowing wave abnormal in 5 patients.All patients were treated with combined first-line immunomodulatory therapies with steroids, intravenous immunoglobulin, or plasma exchange. Five patients were fullly recoveried, 4 patients were improved with residual symptoms. Conclusions Severe anti-NMDAR encephalitis may present progress quickly mental behavior change, epilepsy, and disturbance of consciousness, movement disorders, autonomic nerve dysfunction.Which accompanied with tumor is rare.Most patients with active immunotherapy can get good prognosis.

Fanconi anemia (FA) is an rare autosomal recessive inherited disease which manifests progressive marrow failure, congenital bone malformation, high risk to cancers and so on. Chromatin of FA cells display auto-instability and high hypersensitivity to interstrand DNA cross-links such as mitomycin C. As normally FA develop into acute myeloid leukemia easily, it has been regarded as pre-leukemia state. Till now 11 FA genes have been found and play a role in sustaining stability of gene groups through the same mechanism. As an active connecting protein, FANCF protein play an important part in correct FA complex formation. Which makes FANCD2 single ubiquitin. Ubiquitin FANCD2 induces chromatin and BRCA1 interact, and repair injured DNA. FA gene defect makes gene group instable and increases the risk of chromatin collapse, which finally leads to acute myeloid leukemia and myelodysplastic syndrome.

Objective: To study the effective initiating time of the maxillary protraction therapy for the children with skeletal classⅢ malocclusion. Methods: 20 cases with class Ⅲ malocclusion were divided into 2 groups: older group (9～ 12 years old) and younger group(5～8 years old), and treated with maxillary protraction. Before and after treatment cephalometric radiographs were taken and analyzed. Results: Good effects were found in both groups. The treatment in the younger patients showed the advantages of shorter treatment period, more skeletal changes, less dental changes and less side effects. Conclusion: Earlier maxillary protraction is more beneficial to the children with Angle Ⅲ malocclusion.