Objective:To investigate the cesarean perioperative usage in patients, and the rationality of drug evaluation.Methods: A retrospective analysis in February 2012 to August 2013 in our hospital for treatment of cesarean perioperative clinical information on the use of antimicrobial agents for statistics, and use frequency analysis method for analysis.Results: All patients with the highest rates of antibiotic Ornidazole, the highest consumption of Ornidazole, the highest amount of sales Ornidazole, cefotiam, the highest frequency of drug use Ornidazole use reasonable potassium penicillin drugs, cefotiam, ornidazole; most unreasonable use drugs penicillin, cefazolin amount of sorting/DDDs (medication on the number) were higher than a sort; cefmetazole the amount of sorting/ DDDs (medication on the number) Sort lowest value, and less than 1.Ratio of only 0.56% monotherapy, combination therapy of two drugs highest proportion is 76.67%. Conclusion: Perioperative cesarean section used antibiotics exists that use a longer time, the problem of improper dosage should strengthen supervision and improve the rational use of medicines in hospitals level.

The paper introduces concept, value, content, composition and frame theory of the overall informatization framework, an-alyzes the requirements of regional health informatization, summarizes the main modes of regional health informatization construction in China and elaborates the overall framework of regional health informatization and positioning of each composing factors, in order to provide references for regional health informatization construction in various regions.

Objective To investigate the relationship of serum uric acid(SUA) with type 2 diabetes mellitus and diabetic macrovascular complications and to study the influential factors of SUA.Methods Recruited were eighty type 2 diabetic patients(group B),ninety-two type 2 diabetic patients with coronary artery disease(group C) and one hundred and twelve healthy controls(group A) whose qualitative urine protein assay were negative.Serum concentrations of uric acid and other biochemical materials were assayed at a fasting state.The sensitivity of insulin was also evaluated.Results(1) The SUA levels in group A,B and C were(280±81)(257±76) and (302±72) mmol/L respectively;SUA in group B was lower than that in group A(P=0.037) or group C(P=0.000) and SUA in group C tended to be higher than that in group A(P=0.050).(2) SUA level significantly increased in man than in woman(P=0.001).(3) The independent influential factors of SUA were WHR(R=0.354) in man,and BMI(R=0.286) and age(R=0.623) in woman.(4) After adjusting the age,sex,distribution of body fat and serum lipid level, the logistic regression analysis of group B and C showed that hyperuricemia was the independent risk factor for diabetic macrovascular complications,and this was especially obvious in smoker or hypertensive patient.Conclusions SUA in type 2 diabetic patients is lower than that in both healthy controls and type 2 diabetic patients with coronary disease.The level and contributing factors of SUA are different between men and women.

Reaction conditions of docosahexaenoic acid (DHA) ester complexing with silver ion were reported. Ultraviolet spectral features of DHA ester and its complex with silver ion were investigated. Shifts of characteristic absorption peak before and after the complexing reactions were observed And the structure of complex and complexing mechanism were discovered.

OBJECTIVE:To establish the quality standard for Qiwei kangti powders.METHODS:Radix Astragali,Angelica sinensis,Salvia miltiorrhiza were identified by TLC.The content of tanshinone Ⅱ A(the chief content in Salvia milti-orrhiza) was determined by HPLC.RESULTS:The TLC spots developed were fairly specific.Tanshinone Ⅱ A showed a good linear relationship at a range of 5.44～32.64 ?g?mL-1(r=0.999 8),and its average recovery was 99.54%(RSD=0.955%,n=9).CONCLUSION:The established quality standard is applicable for the quality control of Qiwei kangti powders.

The remodeling and reparative process post myocardial infarction (MI) can be divided into three phases:the inflammatory phase,the proliferative phase and the stable phase.The inflammatory immune response plays an important part in the process of cardiac remodeling.First of all,the initiation of inflammatory response relies on the activation of innate immunity with a group of pro-inflammatory cytokines,chemokines and adhesion molecules.These molecules lead to the infiltration of the infarct area with neutrophils and mononuclear cells,further clearing the wound from dead cardiomyocytes and matrix debris.After resolution of inflammatory response,reparative cells and cytokines infiltrate into the heart and promote the differentiation and growth of myofibroblasts and endothelial cells,contributing to wound contraction as well as producing fiber tissue to form a scar.Moreover,overactive immune responses could accentuate infarct injury and dilative remodeling while deficiency of inflammation leads to insufficient repair,which highlights the dual function of the immune response in myocardial injury and repair post MI.Also the intense immune response along with fibrosis in non-infarct area is also closely associated with adverse remodeling.Thus,targeting specific factors in the inflammatory reaction may hold promise in patients with MI.

Purpose To study the diagnostic value of imprint cytology and to improve the accuracy of the rapid diagnosis of sentinel lymph node (SLN) during the operation of breast cancer.Methods 169 SLNs during 67 operations of breast cancer were detected by both frozen section and imprint cytology, and the results were compared with the histopathological diagnosis of permanent sections.Results Of 169 SLNs, 163 cases were diagnosed correctly with frozen section (163/169, 96.45%); 162 cases were diagnosed correctly with imprint cytology (162/169,95.86%);and 166 cases were diagnosed correctly by combination of imprint cytology and frozen section (166/169,98.22%).Conclusions Combination of imprint cytology and frozen section could increase the accuracy of the rapid diagnosis of SLN in breast cancinoma operation.

Cytochrome P450 are abundant in Streptomyces which play an important role in the biosynthesis of secondary products and metabolism of exotic chemicals of Streptomyces. Recent progress and function of cytochrome P450 in Streptomyces were reviewed in this paper. The problems in study of Streptomyces Cytochrome P450, and the prospects for future study of cytochrome P450 and its application were also discussed.

Cardiomyopathy, Hypertrophic ; Humans

Objective To investigate the expressions and significance of PAX-5, OCT-2 and BOB.1 in Hodgkin lymphoma (HL). Methods Immunohistochemical method was used to detect the expressions of CD30, CD15, PAX-5, OCT-2, BOB.1, CD20 and CD3 in 44 samples of formalin-fixed, paraffin-embedded tissues of HL. The histological classification was carried out according to the WHO classification for tumors of hematopoietic and lymphoid tissues (2001). Results In all 44 cases, 3 (6.8) were nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) and 41 (93.2) were classical Hodgkin lymphoma (CHL). In Hodgkin and Reed Sternberg cells, CD30 were expressed in 36 samples (81.8), CD15 in 27 (61.4), CD20 in 14 (31.8), PAX-5 in 43 (97.7), OCT-2 in 14 (31.8), and BOB.1 in 7 (15.9). All samples of NLPHL expressed OCT-2 and BOB.1, while in the samples of CHL, 30 samples (73.2) expressed both OCT-2 and BOB.1, 7 (17.1) expressed only OCT-2, 1 (2.4) expressed only BOB.1 and all were negative for CD30. Conclusion Hodgkin lymphoma is a rare neoplasm with uncertain cause and difficult to diagnose. The detection of PAX-5, OCT-2 , BOB.1 in combination with CD30, CD15 will conduce to the diagnosis and differential diagnosis of Hodgkin lymphoma.