Objective To investigate the value of prenatal ultrasound observation of subaortic conical connection in the diagnosis of complete transposition of great arteries(TGA).Methods Echocardiography findings of 22 cases with complete TGA confirmed by autopsy were retrospectively analyzed and summarized.Results All cases were shown subaortic conical connection on two-dimensional echocardiography,the two great arteries were parallel in 18 cases on left ventricular long-axis view,the character of normal right ventricular outflow tract surrounding the aortic root disappeared in 17 cases.There were 13 cases with ventricular septal defect and 2 cases with left ventricular outflow tract obstruction.Aorta and pulmonary artery were shown in right anterior and left posterior position among 20 cases,and in anterior and posterior position in 2 cases.Conclusions Prenatal ultrasound observation of subaortic conical connection is of great value in the diagnosis of complete TGA.

Objective To explore the imaging characteristics of malignant lymphoma of intestinal tract.Methods Thirty-two cases of malignant intestinal lymphoma proved operatively and pathologically were studied .All cases were subjected to Ba-meal or double contrast Ba-enema examinations. There were 10 cases studied by CT scan and 19 cases by B-ultrasonography.Results By Barium studies we found 20 cases of lesions involving the small intestine or ileocecal junction and 12 involving the large intestine. In the former subgroup , we found regional dilatation of small intestine in 6, multiple intraluminal polypoid filling defects in 7, intestinal wall infiltration in 4, intraluminal nodular proliferation with ulcer formation in 3; while in the latter subgroup ,there were polypoid masses seen in 6, narrowing of intestinal lumen in 5 and coarse intestinal mucosa in 1.On CT scan , we found irregular thickening of intestinal wall in 5 cases , eccentric intraluminal mass in 2 and intestinal dilatation associated with thickening of intestinal wall in 3. B-ultrasonography showed beltoid low echo thickened intestinal wall in 5 cases ,pseudo kidney sign in 6 and lumpy low echoes in 2. Conclusion Barium study , CT scan and B-ultrasonography have different specific diagnostic characteristics for malignant intestinal lymphoma.In combination with these examinations are mutually beneficial in the diagnostic process.

Objective: To establish a method for the determination of gastrodine in Tianma Formula Granule. Methods: HPLC was used with LiChrospherR 100 column, MeOH-phosphate solution(contain KH2PO4 and Na2HPO4 each 0.1mol/L)-water(1.5:3:95.5) as mobile phase and detection wavelength at 270nm. Results: Gastrodine showed a good linearity in the range of 1.638～14.742?g. The average recovery was 98.17 %and RSD was 1.39 %(n=5). Conclusion: This method is simple, accurate and with good reproducibility, and can be used for the quality control of Tianma Formula Granule.

Objective: To determine the extract from Radix Astragali. Methods : Astragaloside IV in extract from Radix Astragali was determined by TLC-Scanning. Results : The linear relationship was at the rang of 0.78 ?g～ 4.68 ?g. The average recovery was 99.06% ( RSD=1.17% and n =5). Conclusion : The method is available with a good reproducibility. The pretreatment is simple and easy to operate.

Objective To investigate the clinical value of fetal echocardiography in prenatal diagnosis of complete vascular ring. Methods Ultrasound images of 6 cases with complete vascular ring were retrospectively analysed and summarized, all cases were confirmed by autopsy after termination of pregnancy. Results Right aortic arch and left ductus arteriosus formed U shaped comlete vascular ring coursing around the trachea in 5 cases, left aortic arch and right aortic arch formed O shaped complete vascular ring in 1 case on three-vessel trachea view. Color Dopple flow imaging aided in identifying various components of the vascular ring. Conclusions Fetal echocardiography is of great clinical value in prenatal diagnosis of complete vascular ring. Three-vessel trachea view is important for screening with particular attention to the relationship of the aortic and duct arches to the trachea.

Objective To investigate the clinical value of fetal echocardiography in prenatal diagnosis of total anomalous pulmonary venous connection(TAPVC). Methods Ultrasound images of ten fetuses with TAPVC were retrospectively analysed and compared with pathologic results. Results Ten fetuses were diagnosed TAPVC by prenatal ultrasound, seven cases were confirmed by autopsy after termination of pregnancy,three ceses were unable to be followed up. Among seven cases confirmed by autopsy, prenatal ultrasound findings showed left atrium were extremely small and no pulmonary vein was observed draining to left atrium. Five fetuses with common pulmonary vein showed widen drainage cavum and high-speed vein spectrum. Three fetuses combined with extracardiac malformations. Conclusions Fetal echocardiography has an important clinical value in diagnosing TAPVC.

Objective To investigate the relationship between MRI signal type and CT structural characteristics on lumbar hy-perostogeny ,and the possible mechanism of vertebral body remodeling on degenerative lumbar spine .Methods Imaging data of for-ty-five subjects who were referred for both MRI and CT imaging of the lumbar spine from July 2011 to January 2012 were retro-spectively analyzed .Volume Rendering(VR) and Multi-Planar Reformation(MPR) were used to observe structural characteristics of osteophyte .Osteophyte formation ,MRI signal type and CT features of osteophyte were recorded ,then analyzed their relationship . Results 45 subjects contain 225 vertebral bodies ,there were 38 vertebral bodies containing osteophyte visible to naked eye .The four types of MRI signal were type Ⅰ to type Ⅳ ,accounting for 2(5 .3% ) ,4(10 .5% ) ,10(26 .3% ) and 22(57 .9% ) ,respectively . The three types of CT structural characteristics are type A to type C ,accounting for 4(10 .5% ) ,11(28 .9% ) and 23(60 .5% ) ,re-spectively .The main MRI signal of type A is type Ⅱ(100% ) ,and that of type B and C are both type Ⅳ(72 .7% and 65 .2% ) .Con-clusion There is a corresponding relation between MRI signal type and CT structural characteristics on lumbar hyperostogeny . Constant reconstruction of osteophyte remodels vertebral body on degenerative lumbar spine .

Objective To investigate the application potentiality of dynamic three-dimensional contrast-enhanced ultrasound (3D-CEUS) in showing vascular patterns of hepatic tumors.Methods Total of 65 hepatic tumors were examined with two-dimensional contrast-enhanced ultrasound (2D-CEUS) and dynamic 3D-CEUS and make statistical comparison between two imaging modes in aspects of enhancement patterns,spatial relationships of tumors and vascularity of different hepatic tumors.Results Dynamic 3D-CEUS showed the same enhancement patterns with 2D-CEUS.However,Dynamic 3D-CEUS was superior to 2D-CEUS in the display of spatial relationships of hepatic tumors and vascularity(P ＜0.05).The vascularity between benign and malignant hepatic tumors was statistically significant (P ＜ 0.05).Conclusions Dynamic 3D-CEUS is a useful technique in the differential diagnosis of hepatic tumors as well as 2D-CEUS,and dynamic 3D-CEUS displays the spatial relationship of hepatic tumors and vascularity more visually and comprehensively,which provides additional beneficial information for the diagnosis and therapy of hepatic tumors.

Objective To compare the diagnostic value of MR examination with fast imaging employing steady state acquisition (FIESTA) and single shot fast spin echo (SSFSE) sequences for normal fetal thymuses.Methods Totally 366 normal fetuses were examined using MRI with FIESTA and SSFSE sequences,and the anatomy and MR manifestations of thymuses were observed.Kappa analysis and x2 test were performed.The transverse area (TA) and transverse diameter (TD) were measured on the "three vessel" level,while the superoinferior diameter (SID) was measured on the sagittal level.The mean value of these parameters at different gestational were calculated,and the regression equations of each parameter and gestational age were fitted.Results Two doctors had good agreements with the images of FIESTA and SSFSE sequences (Kappa=0.745,0.802,both P＜0.01).The clear rate of FIESTA and SSFSE sequences was 86.34％ (632/732) and 37.70％ (276/732) respectively,and the differences were significant (x2 =367.520,P＜0.001).The thymic size increased with the gestational age,and the regression equations and correlation coefficients were:TA =-5.80 + 0.35 ×gestational (r=0.820,P＜0.01),TD=-14.59+1.63×gestational (r=0.817,P＜0.01),and SID=-9.63+1.44×gestational (r=0.778,P＜0.01).Conclusion The subtle structure and contour of fetal thymus showed with FIESTA sequence are clearer than those of SSFSE sequence.MRI can clearly show fetal thymus after 22 weeks of pregnancy.

Objective To explore the value of prenatal MRI signs in diagnosis of placenta accreta.Methods MRI data of 163 pregnant women with suspected placenta accreta were retrospectively reviewed.According to the results of cesarean section,they were divided into placenta accreta group (n =136) or without placenta accreta group (n =27).The differencesof MRI signs between the two groups were compared.Taking cesarean section results as the gold standard,the sensitivity,specificity,positive and negative predictive value of MRI signs were calculated,respectively.Results Uterine bulging,abnormal vessels and hypointense T2WI bands at junction of placental and myometrium,as well as uterine recess had statistical differences between the two groups (all P＜0.05).No statistical difference of placental heterogeneity,focal interruptions in myometrial wall,uterine penetration and parametrium implantation nor protrusion of placenta into cervix was found between the two groups (all P＞0.05).The MRI signs of uterine penetration and parametrium implantation,uterine recess,protrusion of placenta into cervix yielded a specificity and positive predictive value of 100％,respectively.Conclusion Prenatal MRI has high efficacy in the diagnosis of placenta accrete.Placenta accrete should be highly suspected especially in the presence of uterine penetration and parametrium implantation,uterine recess and protrusion of placenta into the cervix.