Objective To compare the curative effects of CT-guided ethanol injection and lauromacrogol injection into the sac cavity in treating ovarian endometriosis cysts. Methods A total of 86 patients with ovarian endometriosis cyst were enrolled in this study. The patients were divided into ethanol group (n=44) and lauromacrogol group (n=42). Under CT guidance, injections of ethanol or lauromacrogol into the sac cavity of ovarian endometriosis cysts were respectively performed for the patients of both groups. The patients were followed up for six months, and the curative effects and the complications were analyzed. Results Six months after the treatment, the cure rates of ethanol group and lauromacrogol group were 95.50%and 92.86%respectively, and no statistically significant difference in cure rate existed between the two groups (P>0.05). The preoperative serum CA125 levels of the ethanol group and lauromacrogol group were (48.42±23.68)μg/L and(49.21±22.83) μg/L respectively, and the post operative ones were (23.56±5.89) μg/L and (25.49± 6.10) μg/L respectively; the differences between the preoperative data and the postoperative data were statistically significant in both groups (P<0.05), although the differences in serum CA125 levels between the two groups were not significant (P>0.05). The incidence of postoperative complications in the lauromacrogol group was obviously lower than that in the ethanol group (P<0.05). The cure time in the ethanol group was shorter than that in the lauromacrogol group, although the difference was not significant after six months. Conclusion For the treatment of ovarian endometriosis cysts, CT-guided lauromacrogol injection into the sac cavity has reliable curative effect. Compared to ethanol injection, injection of lauromacrogol is safer and has fewer adverse reactions. Therefore, this technique should be recommended in clinical practice. Serum CA125 can be used as an indicator for the evaluation of curative effect.

This paper describes the clinical pharmacists ’participation in the diagnosis and treatment for a case of disseminated neonatal herpes simplex virus （HSV）type Ⅱ infection with fever as the initial symptom and without skin and mucous membrane involvement. Clinical pharmacists assessed the newborn ’s condition ，inquired about the disease history and medication status of the child’s mother hospitalized in the department of obstetrics ，reviewed the literature ，analyzed that the fever of the child might be related to the medical history of the mother ，and considered that the child might have neonatal HSV infection . It was suggested to use acyclovir 20 mg/kg intravenously for q 8 h immediately after completing virus -related testing ，and closely monitor the common adverse drug reactions of acyclovir . The doctors accepted the consultation advice . The newborn was diagnosed as disseminated neonatal HSV type Ⅱ infection. After treatment ，the child ’s condition was relatively stable and the doctors consulted clinical pharmacists again to help formulate the follow -up drug treatment plan and monitoring plan for the patient . After reviewing relevant literature，clinical pharmacists suggested that after 21 days of intravenous acyclovir treatment ，oral acyclovir 300 mg/m2 q8 h should be continued for 6 months；moreover，common adverse drug reactions should be monitored and neurological development should be evaluated during oral acyclovir treatment ，all of which were accepted by physicians . No adverse drug reactions occurred during intravenous administration of acyclovir ， serum creatinine and urea increased in the 4th week of oral acyclovir administration，but returned to normal after drug withdrawal . The baby was followed up to 1 year old ，and the prognosis was good without neurological sequelae . Clinical pharmacists enabled the clinicians to clarify the treatment strategy and also reduced the risk of medication for the patient by participating in the pharmaceutical consultation . Clinical pharmacists play an cstc active and effective role in the medication treatment ，which fully embodies the professional value in multidisciplinary collaborative diagnosis and treatment .