1.Meta - analysis of the risk factor for endophthalmitis in patients after cataract surgery
Fei, WEN ; Bin, LI ; Fa-Wen, LI
International Eye Science 2016;16(7):1261-1264
AIM: To explore the main risk factors related to the incidence of endophthalmitis in patients after cataract surgery in China and to provide evidence for prevention.METHODS: The results of 5 studies on the main risk factors of endophthalmitis in patients after cataract surgery were analyzed by Meta-analysis method.
RESULTS: The pooled odds ratio values and 95% CI of age(≥70), diabetes, vitreous overflow, operative time ( ≥ 10min ), common operating room and control of using time of topical anesthetic were 1. 81(95% CI: 1. 43-1. 69),3. 66 (95% CI: 1. 64 - 8. 16),2. 21 (95% CI: 1. 46 -3. 32),3. 54 (95% CI: 2. 47 - 5. 06),2. 77 (95% CI: 2. 07 -3. 72),2. 09(95% CI: 1. 53-2. 86).
CONCLUSION: The main risk factors of endophthalmitis were the age(≥70), diabetes, vitreous overflow, operative time(≥10min), common operating room and control of using time of topical anesthetic.
2.Dynamic monitoring risk of anti-hepatoma new drug development.
Jing ZHANG ; Wei FAN ; Hong-Fa LI ; Shu-Li MAN ; Zhen LIU ; Wen-Yuan GAO
China Journal of Chinese Materia Medica 2014;39(20):4050-4053
Risk monitoring of new Chinese patent anti-hepatoma drugs is tracking recognized risks and residual risks, identifying emerging risk and ensure the implementation of the plan, estimating the process of reducing effectiveness. The paper is mainly through understanding the status of Chinese patent anti-hepatoma drugs, the content, characteristic and analysis method of dynamic risk monitoring, and then select the risk control indicators, collect risk information. Finally, puts forward the thought of anti-hepatoma drugs listed evaluation in our country, and try to establish the model of dynamic risk management of anti-hepatoma drugs.
Antineoplastic Agents, Phytogenic
;
adverse effects
;
economics
;
therapeutic use
;
Carcinoma, Hepatocellular
;
drug therapy
;
Drug Discovery
;
economics
;
legislation & jurisprudence
;
organization & administration
;
Drug and Narcotic Control
;
economics
;
legislation & jurisprudence
;
organization & administration
;
Drugs, Chinese Herbal
;
adverse effects
;
economics
;
therapeutic use
;
Humans
;
Liver Neoplasms
;
drug therapy
;
Product Surveillance, Postmarketing
3.On Improving the Capability of Standardized Training Residency in Internal Intensive Medicine
Fa-Ming HE ; Qing-Wen TANG ; Fang XU ; Xiao-Jun LI ;
Chinese Journal of Medical Education Research 2006;0(07):-
Emergency medicine and critical care medicine are the new contents in standardized training of residency.The system of standardized training residency lacks for a traditional way to refer.According to the characteristic of the subjects and the practical situation,this paper discusses the methods of training in studying basic theory,idea education,improving technology and strain capability on improving the capability of standardized training residency in internal intensive medicine.
4.Graded ethanol precipitation method on physicochemical properties and antioxidant activities of polysaccharides extracted from Astragalus Radix.
Hong-fa LI ; Song-bo GUO ; Shu-li MAN ; Ya-ya FAN ; Ting-ting WANG ; Xia LI ; Wen-yuan GAO
China Journal of Chinese Materia Medica 2015;40(11):2112-2116
Astragalus polysaccharide has been widely used in food and medicinal industry owing to its health-promoting properties. In order to characterize better the relationship among molecular weight, structure-activity and activities, a simple method was used different concentration of ethanol including 30% (PW30), 50% (PW50), 70% (PW70), 75% (PW75), 80% (PW80) and 90% (PW90) to precipitate Astragalus polysaccharides into different molecular weight. As a result, PW90 showed smooth surface and the strongest antioxidant activity among these six fractions (P < 0.05). In conclusion, graded ethanol precipitation was a simple method to separate Astragalus polysaccharides into different molecular weight with different antioxidant activity fractions.
Antioxidants
;
pharmacology
;
Astragalus Plant
;
chemistry
;
Chemical Precipitation
;
Ethanol
;
chemistry
;
Polysaccharides
;
chemistry
;
pharmacology
5.Regularity of drugs compatibility of anti-hepatoma traditional Chinese medicine ancient prescriptions and risk evaluation of anti-hepatoma new drug research and development.
Jing ZHANG ; Hong-Fa LI ; Wei FAN ; Zhen LIU ; Shu-Li MAN ; Shu-Yong SI ; Wen-Yuan GAO
China Journal of Chinese Materia Medica 2014;39(19):3870-3875
Traditional Chinese ancient prescriptions have been used for treatment of liver cancer for a long history and the scientific and rational compatibility is a great wealth for modern research and development (R&D) of new drugs. The research and development of new drugs are often accompanied with a large investment, a long cycle and a high risk, especially for the anti-tumor drugs R&D which are facing more risks and lower successful rate. In this research, the regularity of compatibility of drugs was analyzed from 124 anti-hepatoma ancient prescriptions by computer program. The results can offer help to the R&D of anti-hepatoma new drugs and reduce the risk of drug screening. In addition, we surveyed 22 companies in this field from six provinces such as Beijing, Shanghai, Tianjin and so on and obtained 240 risk assessment questionaires. Then we used qualitative analysis method to interpret the greatest impacts for the risks in the process of R&D, production and sales of anti-hepatoma new drugs. The study provides a basis for anti-liver cancer drugs R&D researchers, who can take effective measures to reduce the R&D risks and improve successful rate.
Carcinoma, Hepatocellular
;
drug therapy
;
history
;
China
;
Drug Discovery
;
history
;
Drug Incompatibility
;
Drug Prescriptions
;
history
;
Drugs, Chinese Herbal
;
history
;
therapeutic use
;
History, Ancient
;
Humans
;
Liver Neoplasms
;
drug therapy
;
history
;
Research
;
history
6.Studies on the Screening of a Cyanide-Degradation Strain and Its Cyanide-Transformation Characteristics*
You-Yan LIU ; Yu-Cai HE ; Qing-Yun LI ; Wen-Liang HAN ; Zhang-Fa TONG ; Yong-Qiang HE ;
Microbiology 1992;0(02):-
A bacterial strain DN25, effective on cyanide-degradation, was isolated from contaminated soil and identified as Alcaligenes sp. on the basis of phenotype analysis and 16S rDNA sequence analysis. It showed great tolerance to the cyanide, which can grow in the medium containing 500mg CN -/L. The suitable condition for the cell growth and boitransformation was pH8.0 and 30oC and the transformation rate for 500mg CN - /L could achieve 99% in 10 h. It has also been found that the screened strain had the ability of K 4Fe(CN) 6 transformation with 96% of transformation rate at 12 h for the concentration of 500 mg CN /L.
7.Effect of psychological capital and social support on job satisfaction among workers in a natural gas field
WU Hui GU Gui zhen LI Fu ran ZHOU Wen hui SHAO Jian zhong YU Shan fa
China Occupational Medicine 2022;49(06):610-614
To explore the effects of psychological capital social support and their interaction on job satisfaction in
Methods
natural gas field workers. A total of 1 473 workers from a natural gas field were selected as the research subjects
,
using convenient sampling method. Job Satisfaction Questionnaire Psychological Capital Questionnaire and Social Support
, Results
Scale were used to investigate the scores of job satisfaction psychological capital and social support level. The
, ,
detection rates of job satisfaction psychological capital and social support in the high level group were 55.9% 52.5% and
,
48.1% respectively. The detection rates of job satisfaction of workers in the high level psychological capital group and high level
(
social support group were higher than those in the low level psychological capital group and low level social support group 67.4%
vs , vs , P )
43.3% 71.9% 41.2% all <0.01 . The results of multivariate logistic regression analysis showed that psychological capital
[ (CI) ( - )
and social support had positive effects on job satisfaction odds ratio and 95% confidence interval were 1.58 1.17 2.41
( - ), , P ] ,
and 2.53 1.82 3.52 respectively all <0.01 . Moreover the psychological capital and social support had additive effect on
[ CI ( - ), CI
job satisfaction relative excess risk of interaction and 95% was 3.07 1.02 5.12 attributable proportion and 95% was
( - ), CI ( - )],
0.48 0.35 0.61 synergy index and 95% was 2.34 1.72 3.16 but there was no multiplication interaction between
(P )Conclusion
psychological capital and social support >0.05 . Psychological capital and social support can positively affect
job satisfaction of natural gas workers. There is an additive interaction between psychological capital and social support on job
,
satisfaction but no multiplicative interaction is found.
Keywords: ; ; ; ; ;
Psychological capital Social support Job satisfaction Interaction Natural gas Worker
8.mf-ERG effective evaluation of early and background diabetic retinopathy
Cun-Wen, PEI ; Li, WEN ; Xue-Mei, FENG ; Shao-Yang, SHI ; Li, FA ; Hong-Yu, WANG ; Yan-Ping, SUN ; Yun-Dong, DUAN ; Hong-Tao, YANG
International Eye Science 2014;(12):2217-2219
AlM: To measure the retinal electrical activities in patients with diabetic retinopathy ( DR ) by applying multifocal electroretinogram ( mf-ERG) and evaluate the degree of visual damage at different stages of DR
METHODS:Thirty cases ( 30 eyes ) aged 50 ~70 years old, excluding other diseases, were as normal group, and 99 cases ( 99 eyes ) diagnosed with type 2 diabetes were as experiment group. The cases received mf-ERG examination in the standard state, respectively. The results were statistically analyzed
RESULTS: For DR patients with early and background stage, the reaction density of mf - ERG P1 wave decreased as the disease worsened, significantly reduced in non - proliferating stage and decreased more significantly in the background of the stage Ⅲ. This showed that in the macula, electrical activity had weakened before the retina without visual or morphological changes, and with the development of the disease, the electrical activity decreased more obviously.
CONCLUSlON:mf-ERG can evaluate the severity of DR, especially suit in the early and background period of DR.
9.Application of SEMG to study the effects of imagery training on back-style high jump.
Wen-Feng LIU ; Yong-Ling CHANG ; Chang-Fa TANG ; Zhen-Zhen HONG ; Li-Qin YIN ; Jin CHEN ; Wen-Ning REN ; Long JIANG ; Jian KUANG
Chinese Journal of Applied Physiology 2013;29(3):260-270
Adolescent
;
Adult
;
Athletic Performance
;
psychology
;
Back
;
physiology
;
Electromyography
;
Exercise
;
physiology
;
Humans
;
Imagery (Psychotherapy)
;
Male
;
Young Adult
10.Treatment of thoracolumbar fractures by rehabilitation exercise using knee pads on the orthopedic traction bed.
Kai-Fa YOU ; Hong-Xi LAI ; Feng-Lin ZOU ; Tian-Fa DENG ; Yu-Hua LI ; Tian-Hua WEN ; Chong-Qing HUANG
China Journal of Orthopaedics and Traumatology 2010;23(4):302-304
OBJECTIVETo discuss the clinical effectiveness in treating thoracolumbar fractures adopting the rehabilitation exercise utilizing knee pads on the orthopedic traction bed.
METHODSFrom June 1996 to June 2006, we studied the clinical effectiveness of thoracolumbar fractures utilizing knee pads on the orthopedic traction bed for rehabilitation exercise. The cases surveyed total 209, 163 of which had full data. There were 98 males and 65 females with the age from 17 to 74 years (mean, 14.5 years). Consulting time after injury from 30 min to 7 days. Fracture site in T11 had 8 cases, in T12 24 cases, in L1 73 cases, in L2 33 cases, in L3 8 cases, in L4 3 cases, in T12 and L1 14 cases. Compression degree of vertebral anterior border: full compression had 1 case,more than 4/5 had 23, more than 2/3 had 67, more than 1/2 had 40, in 1/3 had 46.
RESULTSAmong them, 8 cases with legs paresis no recovery in nerval function or stopping recovery changed methods, and underwent surgical treatment. Others 155 cases were followed up from 2 to 12 years with an average of 3 years and 4 months. The average height of vertebral anterior borders of the 169 injured compressed had increased from 1.55 cm before treatment to 2.70 cm after treatment with an average of 1.15 cm. The height of the injured vertebral anterior borders had recovered from 50.5% (1.55/3.07) before treatment to 89.4% (2.70/3.02) after treatment. Kyphosis angle of the injured vertebral bodies had recovered from 13.25 degrees to -1.6 degrees in average. Twenty-three cases associated with dislocation basic reduction.
CONCLUSIONRehabilitation exercise using knee pads on the orthopedic traction bed can obtain satisfactory clinical effect in treating thoracolumbar fractures, the method is easy. At 3, 7, 10 days after treatment, the height of bed should be adjusted according X-ray.
Adolescent ; Adult ; Aged ; Exercise Therapy ; instrumentation ; methods ; Female ; Follow-Up Studies ; Humans ; Lumbar Vertebrae ; injuries ; physiopathology ; surgery ; Male ; Middle Aged ; Orthopedic Equipment ; Recovery of Function ; Spinal Fractures ; physiopathology ; rehabilitation ; surgery ; Thoracic Vertebrae ; injuries ; physiopathology ; surgery ; Treatment Outcome ; Young Adult