OBJECTIVE:To prepare compound zinc sulfate oral solution and establish its quality control method. METHODS: The oral solution was prepared with zinc sulfate and lysine hydrochloride as chief components. The content of lysine hydrochloride was determined by coordination titration and uv spectrophotometry, respectively, and the stability of the preparation was investigated. RESULTS: The oral solution was colorless or yellowish, with its identification and test results all in conformity with the related stipulation stated in Chinese Pharmacopeia(2005 edition). The average content of zinc sulfate labeled in the sample stood at 101%. The linear range of lysine hydrochloride was 3.2～9.6 ?g?mL-1(r=0.999 9) and its average recovery rate was 99.75%(RSD=0.27%, n=6). The preparation was stable within 6 months storing under room temperature. CONCLUSION: This preparative technology of compound zinc sulfate oral solution is simple and feasible, and the quality of which is stable and controllable.

Objective: To investigate the trend in burden of mental disorders among the elderly in China from 1990 to 2021, so as to provide the basis for formulating prevention, control and intervention measures for mental disorders in this population. Methods: Based on the data of the Global Burden of Disease 2021 (GBD 2021), the number of cases, prevalence, disability-adjusted life years (DALY) and DALY rate of mental disorders among the elderly in China were collected, and standardized prevalence and DALY rate were calculated using the world standard population. The burden of mental disorders was analyzed, and the trend in burden was analyzed using average annual percent change (AAPC). Results: The standardized prevalence and standardized DALY rate of mental disorders among the elderly in China showed upward trends from 1990 to 2021 (AAPC=0.160% and 0.286%, both P<0.05). In 2021, there were 38.944 9 million cases of mental disorders among the elderly in China, the DALY was 5.389 8 million person-years, the standardized prevalence was 14 462.91/105, and the standardized DALY rate was 1 993.69/105, with the increases of 184.12%, 192.90%, 5.71% and 9.60% compared to 1990, respectively. The burden of mental disorders increased significantly among the elderly aged 60 to <65, 65 to <70, 70 to <75, and 75 to <80 years, with the increases of 5.81%, 5.92%, 6.08% and 6.03% in prevalence, and the increases of 10.16%, 10.12%, 10.31% and 9.88% in DALY rates, respectively. Depression and anxiety ranked the top two in standardized prevalence and standardized DALY rates. The standardized prevalence and standardized DALY rate of autism showed the largest increases, at 18.82% and 18.10%, respectively, while congenital intellectual disabilities exhibited the largest decreases, at 36.15% and 29.71%, respectively. The standardized prevalence and standardized DALY rate of mental disorders were higher in women than in men (both P<0.05). Compared to men, women had higher standardized prevalence and standardized DALY rates of depression, anxiety and congenital intellectual disabilities, but lower standardized prevalence and standardized DALY rates of schizophrenia, autism, attention deficit hyperactivity disorder, and other mental disorders (all P<0.05). Conclusion The burden of mental disorders among the elderly population in China showed an upward trend from 1990 to 2021, with heavier burdens observed among women, individuals aged 60 to <80 years, and those with depression and anxiety.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.