1.The association of endocrine-disrupting chemicals exposure, sociodemographic factors, and polycystic ovarian syndrome among reproductive-aged nonpregnant women at the Philippine General Hospital: A case–control study
Erlidia Flores Llamas-Clark ; John Robert Carabeo Medina ; aria Esterlita Tagle Villanueva-Uy ; Francisco M. Heralde III ; Maria Stephanie Fay Samadan Cagayan ; Paulyn Jean Buenaflor Rosell-Ubial ; Michael C. Velarde
Philippine Journal of Obstetrics and Gynecology 2024;48(3):151-161
BACKGROUND:
Polycystic ovarian syndrome (PCOS) is a prevalent condition affecting women of reproductive age, characterized by metabolic, endocrine, and reproductive disturbances including insulin resistance, abnormal uterine bleeding, infertility, and hyperandrogenism, and is associated with diabetes and cardiovascular disease. The etiology of PCOS is unclear and exposure to endocrine-disrupting chemicals (EDCs) present in everyday products may play a role by disrupting hormonal pathways.
OBJECTIVES:
To determine the association between exposure to EDC-containing products, sociodemographic factors, and PCOS diagnosis among nonpregnant reproductive-aged women.
MATERIALS AND METHODS:
A survey assessed the frequency of EDC exposure in homes and workplaces. The Rotterdam Criteria were used for the diagnosis of PCO features with clinical history and ultrasound. The association between PCOS and EDC exposure was determined using Chi-square and logistic regression analysis.
RESULTS:
The study identified significant sociodemographic factors associated with PCOS (P < 0.001) including age, civil status, and household income. Increased likelihood of PCOS was linked to frequent use of scented candles (odds ratio [OR] = 2.07), cleaning sprays (OR = 2.28), and floor polish (OR = 2.07), exposure to new upholstered furniture (OR = 4.00), thermal receipts (OR = 2.16), and consumption of microwaved and processed foods (OR = 2.60), as well as water sourced from wells (OR = 7.69). Additional associations were found with access to public markets (OR = 0.26) and the use of paper food wrappers (OR = 1.72).
CONCLUSION
These findings suggest that frequent exposure to EDC-containing products and certain sociodemographic factors may contribute to the development of PCOS among women of reproductive age. Results underscore the importance of reducing exposure to EDCs to prevent or mitigate the development of PCOS and other reproductive consequences.
Female
2.Evaluation of female infertility
Philippine Journal of Reproductive Endocrinology and Infertility 2007;4(1):19-24
This paper will focus only on the recommendations or guidelines on the evaluation for female infertility. Most of the recommendations were based on the Fertility Assessment and Treatment for People with Fertility Problems Guideline by the National Institute for Clinical Excellence.
Human
;
Female
;
INFERTILITY, FEMALE
3.Malignancies of the female genital organs, 10 years experience a study of incidence and histopathology.
Tae Sung LEE ; Ki Hyun CHO ; Jung Geol AHN ; Hyeong Jong LEE ; Soon Do CHA ; Tak LEE ; Young Wook SUH
Korean Journal of Obstetrics and Gynecology 1991;34(10):1425-1433
No abstract available.
Female
;
Female*
;
Genitalia, Female*
;
Humans
;
Incidence*
5.Clinical study of transaxillary subpectoral augmentation mammoplasty.
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(4):656-664
No abstract available.
Female
;
Mammaplasty*
6.Synchronous Development of Gastrointestinal Stromal Tumor and Arteriovenous Malformation in the Jejunum: A Case Report.
Sang Hwa SHIM ; Yoon Hee HAN ; Ji Eun KWAK ; Sun Hee CHANG ; Hanseong KIM ; Je G CHI ; Mee JOO
Korean Journal of Pathology 2008;42(3):185-188
Vascular malformations associated with neoplasms are extremely rare. Herein we report an extraordinary coincidence of arteriovenous malformation (AVM) and gastrointestinal stromal tumor (GIST) in the jejunum. A 44-year-old woman presented with melena and anemia. Abdominal computed tomography revealed a highly vascularized, strong early arterial enhancing soft tissue mass in the jejunum, which was confirmed by angiography to be an AVM supplied by the distal jejunal branch of the superior mesenteric artery. An emergency operation was performed due to active gastrointestinal (GI) bleeding. The resected jejunum showed a protruding, mostly solid subserosal mass. The mass was confirmed to be a spindle cell type GIST and was intermingled with the AVM located in the overlying submucosa and muscularis propria. To our knowledge, this is the first reported case of an AVM associated with a GIST. This case masqueraded radiologically as an AVM alone and presented clinically with GI bleeding.
Female
;
Humans
7.Carcinosarcoma (True Malignant Mixed Tumor) of the Parotid Gland: A Report of a Case with Small Cell Carcinoma as the Carcinoma Component.
Hun Soo KIM ; Hyang Jung CHO ; Yeun Tai CHUNG ; Soon Ah PARK ; Hae Joong CHO ; Jin Man KIM
Korean Journal of Pathology 2008;42(3):175-180
True malignant mixed tumor (carcinosarcoma) of the salivary gland is an extremely rare tumor. By definition, it is a heterologous neoplasm that's composed of both malignant epithelial and mesenchymal components. We report here on a case of an 83 year old female patient with a parotid gland mass. Histologic examination showed a biphasic pattern of growth with both a poorly differentiated epithelial component and a sarcomatous spindle cell background. The immunohistochemical and ultrastructural findings support the diagnosis of a small cell neuroendocrine epithelial tumor and an undifferentiated malignant mesenchymal features. The histologic and ultrastructural features along with the immunohistochemical findings are presented. We also review the literature and we discuss the different opinions on the exact histogenesis of the true malignant mixed tumor of the salivary gland. To the best of our knowledge, this histological pattern has not been previously reported in the English medical literature.
Female
;
Humans
8.Benign Fibrous Histiocytoma of Spinal Cord.
Hae Joo NAM ; Won Hee CHOI ; Tae Sook LEE
Korean Journal of Pathology 1988;22(4):510-514
Fibrous histiocytoma composed of fibroblasts and histiocytes is quite variable in histologic pattern. The biologic behavior is unpredictable by histologic ground. This tumor is well-known in subcutaneous tissue and deep soft tissue, but quite rare in central nervous system. We experienced a case of the fibrous histiocytoma involving the dura mater of spinal cord in a 26 year old female patient. In gross findings, the mass was a well demarcated, ovoid mass attached to the dura matter, and measured 2.5x1.5 cm in diameter. The cut surface was rubbery, solid, gray-white or yellow. Microscopically, the lesion consisted of polyhedral cells with round or oval nuclei and faintly eosinophilic or vaculoated cytoplasm, and multinucleated giant cells. Some giant cells were Touton-type. Composing cells were bland-looking. Mitotic figures were average 3 per 10 high power fields.
Female
;
Humans
9.A clinical study of endometriosis.
Seon Je HWANG ; Yong Ho RHO ; Wook Hyeon KWON ; Hee Dong YANG ; Jeong Sang GWAK
Korean Journal of Obstetrics and Gynecology 1993;36(7):3028-3033
No abstract available.
Endometriosis*
;
Female