1.Risk of COVID-19 outcomes among healthcare workers: Findings from the Philippine CORONA retrospective cohort study.
Adrian I. ESPIRITU ; Carl Froilan D. LEOCHICO ; Isabella E. SUPNET ; Emilio Q. VILLANUEVA III ; Marie Charmaine C. SY ; Veeda Michelle M. ANLACAN ; Roland Dominic G. JAMORA
Acta Medica Philippina 2025;59(2):25-32
OBJECTIVES
While many healthcare workers (HCWs) contracted COVID-19 during the pandemic, more information is needed to fully understand the potential for adverse health effects in this population segment. The aim of the present study is to examine the association between healthcare worker status and neurologic and clinical outcomes in COVID-19 infected inpatients.
METHODSUsing the nationwide database provided by the retrospective cohort Philippine CORONA study, we extracted relevant data and performed a secondary analysis primarily focusing on the presentation and outcomes of healthcare workers. Propensity score matching in a 3:1 ratio was performed to match HCWs and non-HCWs. We performed multiple logistic and Cox regression analyses to determine the relationship between HCWs and COVID-19 clinical outcomes.
RESULTSWe included 3,362 patients infected with COVID-19; of which, 854 were HCWs. Among the HCWs, a total of 31 (3.63%) and 45 (5.27%) had the primary outcomes of in-hospital mortality and respiratory failure, respectively. For both overall and 3:1 propensity-matched cohorts, being an HCW significantly decreased the odds of the following outcomes: severe/critical COVID-19 at nadir; in-hospital mortality; respiratory failure; intensive care unit admission; and hospital stay >14 days.
CONCLUSIONWe found that being an HCW is not associated with worse neurologic and clinical outcomes among patients hospitalized for COVID-19.
Human ; Health Personnel ; Covid-19 ; Sars-cov-2 ; Cohort Studies
2.Umbilical endometriosis: A case series on the different approaches in management
Janelle Marie Guinto Doloiras ; Regina Paz A. Tan-Espiritu
Philippine Journal of Obstetrics and Gynecology 2025;49(1):68-73
Endometriosis is defined as the presence and growth of the glands and stroma of the lining of the uterus in an aberrant or heterotopic location. The cause of endometriosis is uncertain and involves many mechanisms including retrograde menstruation, vascular dissemination, metaplasia, immunologic, and hormonal influences to name a few. Primary umbilical endometriosis is a rare disorder defined as the presence of ectopic endometrial tissue within the umbilicus. It commonly presents with catamenial pain and bleeding from an umbilical nodule. It is a rare condition and treatment has not been standardized yet due to the limited number of cases. Surgical management is the treatment of choice to avoid local recurrence while hormone therapy may be used preoperatively for symptomatic relief. This paper reports a series of recently observed cases of primary umbilical endometriosis with main aim of discussing the different approaches in the management of this rare condition.
Human ; Female ; Adolescent: 13-18 Yrs Old ; Child: 6-12 Yrs Old ; Umbilicus ; Endometriosis
3.Risk of COVID-19 outcomes among healthcare workers: Findings from the Philippine CORONA retrospective cohort study
Adrian I. Espiritu ; Carl Froilan D. Leochico ; Isabella E. Supnet ; Emilio Q. Villanueva III ; Marie Charmaine C. Sy ; Veeda Michelle M. Anlacan ; Roland Dominic G. Jamora
Acta Medica Philippina 2024;58(Early Access 2024):1-8
Objectives:
While many healthcare workers (HCWs) contracted COVID-19 during the pandemic, more information is needed to fully understand the potential for adverse health effects in this population segment. The aim of the present study is to examine the association between healthcare worker status and neurologic and clinical outcomes in COVID-19 infected inpatients.
Methods:
Using the nationwide database provided by the retrospective cohort Philippine CORONA study, we
extracted relevant data and performed a secondary analysis primarily focusing on the presentation and outcomes of healthcare workers. Propensity score matching in a 3:1 ratio was performed to match HCWs and non-HCWs. We performed multiple logistic and Cox regression analyses to determine the relationship between HCWs and COVID-19 clinical outcomes.
Results:
We included 3,362 patients infected with COVID-19; of which, 854 were HCWs. Among the HCWs, a total
of 31 (3.63%) and 45 (5.27%) had the primary outcomes of in-hospital mortality and respiratory failure, respectively. For both overall and 3:1 propensity-matched cohorts, being an HCW significantly decreased the odds of the following outcomes: severe/critical COVID-19 at nadir; in-hospital mortality; respiratory failure; intensive care unit admission; and hospital stay >14 days.
Conclusion
We found that being an HCW is not associated with worse neurologic and clinical outcomes among
patients hospitalized for COVID-19.
Health Personnel
;
COVID-19
;
SARS-CoV-2
;
Cohort Studies
4.A case of diffuse cutaneous systemic sclerosis in a 52-year-old Filipino woman
La Verne Ivan H. Espiritu ; Mikiko L. Yamanaka
Journal of the Philippine Dermatological Society 2024;33(Suppl 1):3-3
Diffuse cutaneous Systemic Sclerosis (dsSSc) is an uncommon subtype of Scleroderma or Systemic Sclerosis (SSc), a multisystemic autoimmune disease. Philippine reports remain limited, hence there is a need to review this condition to accurately diagnose and manage Filipino patients. We present the case of a 52-year old Filipino female with a one-year history of pruritus and generalized skin thickening presenting as multiple, well-defined, hyperpigmented patches and plaques. She also presented with systemic symptoms like fever, dysphagia, and finger tenderness, swelling, numbness, and color changes upon exposure to extreme temperatures known as Raynaud’s Phenomenon. Clinical findings, alongside dermoscopic, histopathologic, nail capillaroscopy, and diagnostic data, confirmed dsSSc diagnosis with complications like Barrett’s Esophagus and Interstitial Lung Disease. Treatment options include corticosteroids, emollients, immunosuppressants, biologics, and phototherapy. Multidisciplinary teams are essential to address systemic complications.
Human ; Female ; Middle Aged: 45-64 Yrs Old ; Scleroderma, Systemic
5.Latitude and seasons influence the prevalence of Theileria orientalis and affect the hematology of non-grazed dairy cows in Korea
Hector ESPIRITU ; Hee-Woon LEE ; Md Shohel Al FARUK ; Su-Jeong JIN ; Sang-Suk LEE ; Yong-Il CHO
Parasites, Hosts and Diseases 2024;62(1):64-74
This pilot study aimed to investigate the effects of regional and seasonal variations on the prevalence of Theileria orientalis and the hematological profile of non-grazed dairy cows in Korea. A total of 365 clinically healthy lactating Holstein Friesian cows from 26 dairy farms in 7 provinces that were categorized into northern, central, and southern regions were sampled during the warm period from July to August and the cold period from October to December. The detection of T. orientalis major piroplasm surface protein gene and the hematology non-grazed dairy cows were analyzed using peripheral blood samples. The T. orientalis prevalence was 20.0% (73/365). The prevalence in the southern region was 35.9%, which was significantly higher than that in the central (21.6%) and northern (12.9%) regions (P < 0.05). The prevalence during warm period was higher (43.0%) than that during the cold season (13.5%). The infected cows showed significantly lower erythrocyte counts in the southern region (5.8 ± 0.6 M/µl) and during the warm period (5.8 ± 0.7 M/µl) compared with those in the central and northern regions and during the cold season, which affected the extended RBC parameters, including hematocrit and hemoglobin concentrations. Our findings revealed the prevalence of T. orientalis in Korea, highlighting its high occurrence during warm periods and in certain geographical regions. Climatic factors could contribute to the health and productivity of cattle, as evidenced by the prevalence of T. orientalis and its negative impact on animals.
6.Prevalence of geriatric syndromes among elderly patients seen in the Rizal-Tagak Family Medicine Clinic: A cross-sectional study.
The Filipino Family Physician 2024;62(2):279-288
BACKGROUND
As the aging population increases, health conditions in older adults require increased attention. Geriatric syndromes are clinical conditions that do not belong to specific disease categories but are concomitantly occurring that significantly affect the functionality and quality of life of older adults. The importance of routine screening of geriatric syndromes was emphasized as this will help in identifying the current conditions and health-related problems of the elderly population in the community, and its implication to their quality of life.
OBJECTIVEThis study aimed to determine the prevalence of the geriatric syndromes among elderly patients seen in the Rizal Tagak Community Geriatrics clinic.
METHODSThis research is a cross-sectional descriptive using the locally available DOH Geriatric Screening Tool for Senior Citizens and FRAIL Index Assessment tool.
RESULTSForty-six patients were included in the study. The results of the study showed that the most prevalent geriatric syndrome is frailty (78.26%), followed by polypharmacy (73.91%), visual problems (67.40%), fall risk (56.62%), urinary incontinence (45.65%), and memory impairment (41.30%). Less prevalent geriatric syndromes were malnutrition (13.04%), depression (10.87%), physical functional incapacity (8.7%), and hearing problems (6.52%).
CONCLUSIONRoutine screening for geriatric syndromes among the elderly is very important as these conditions have serious consequences and impact on the quality of life of the older adults. Early detection of geriatric syndromes will help in implementing early and appropriate interventions to prevent further complications which will be beneficial in promoting healthy aging.
Human ; Aging
7.Mapping the journey of patients with painful diabetic peripheral neuropathy in the Philippines
Rosalina B. Espiritu-Picar ; Bien J. Matawaran ; Jermaine M. Lim ; Priyan Ratnasingham
Acta Medica Philippina 2023;57(6):46-51
Objectives:
Knowing the limited epidemiological studies on painful diabetic peripheral neuropathy (pDPN) in the
Philippines, the present review aimed to map the prevalence of pDPN and identify the associated healthcare gaps.
Materials and Methods:
A systematic search of MEDLINE, Embase and BIOSIS was conducted using predefine inclusion criteria, and relevant studies published in English between 2004 and 2021 were identified. An unstructured literature search was also conducted on public and government websites with no date restriction. Data combined from all sources were synthesized and presented as a simple mean.
Results:
Three studies were considered for final analyses of the 26 articles retrieved from structured and unstructured searches. The sample sizes for the three studies were 103, 172, and 100, respectively. The simple mean prevalence of pDPN was estimated at 26.5%. Awareness of pDPN based on a published study was 89%. According to published studies, screening and diagnosis of pDPN were 65% and 76.7%, respectively. One-third of the patients with pDPN (75%) were treated. No literature is available for adherence and control.
Conclusion
Limited data exist on the different management stages of patients with pDPN in the Philippines. The study analysis will help address the knowledge gaps, improve patient care and pain management, and aid decisionmaking.
diabetes mellitus
;
Philippines
8.Assessing the effectiveness of the Well-Being Through Occupational Participation (WBOP) intervention in promoting Filipino Occupational Therapy Faculty Members' Well-Being: A pilot study
Elena Wong Espiritu ; Natalie Norman Michaels ; Evan Dallas Eidson ; Caroline Stegall ; Victoria Vik ; Chloe Volpi ; Chloe Samter
Philippine Journal of Health Research and Development 2023;27(4):67-77
Background:
Filipino occupational therapy educator emigration and limited preparedness for an academic role has resulted in high university turnovers. Remaining faculty experience decreased well-being due to increased academic role responsibilities.
Objective:
Assess the effectiveness of an occupation-based intervention in promoting Filipino occupational therapy faculty members' well-being.
Methodology:
This pilot study used a convergent mixed-methods design. Participants were recruited to participate through the Philippine Academy of Occupational Therapists and the University of Philippines Manila - Department of Occupational Therapy. Faculty members participated in the Well-Being through Occupational Participation (WBOP) intervention. Quantitative data was analyzed using a Wilcoxon Signed-Rank Test, comparing pre and post-test scores from four standardized measures: Self Compassion Scale Short Form (SCS-SF), Scales of General Well Being (SGWB), Engagement in Meaningful Activities Survey (EMAS), and Occupational Balance Questionnaire 11 (OBQ). Qualitative data was analyzed using a multi-level coding process resulting in three themes.
Results:
Five faculty members participated. The SCS-SF scores (T=15, p=0.042, r=0.64) and SGWB (T=15, p=0.041, r=0.65) scores showed a significant increase post-intervention, with large effect sizes. The OBQ (T=14, p=0.078) and EMAS (T=13.5 p=0.102) post-intervention scores did not reflect a significant increase. From the qualitative data, three themes emerged: time to reflect on well-being and occupational engagement, opportunity to view well-being differently, and increased mindset and intentionality.
Conclusion
Results suggest the WBOP intervention was effective in promoting well-being in these Filipino occupational therapy faculty members. Future intervention implementation may be helpful in positively impacting faculty member well-being. A research study with a larger number of participants is warranted.
Occupational Therapy
9.Exploring factors influencing Essential Intrapartum and Newborn Care (EINC) practice amongst Covid-19 suspected mothers: a qualitative study.
Danielle Laya T. Castro ; Clarisse Joyce S. Espiritu ; Marie Angelique S. Magdangal ; Rafael Adriano P. Nalupta ; Albert Paul M. Surposa
Philippine Journal of Health Research and Development 2023;27(2):1-
BACKGROUND:
The practice of Unang Yakap or Essential Intrapartum and Newborn Care (EINC) during the COVID-19 pandemic poses a safety concern with regards to a newborn’s exposure to their COVID-19 suspected mother.
OBJECTIVES:
This study aims to describe the experiences of COVID-19-suspected mothers and explore the factors influencing their decision to allow healthcare professionals to practice full EINC. Specifically, it aims to: 1) describe the experiences of mothers prior to, during, and immediately after delivery, and during postpartum care leading to their decision; and 2) explore the factors that influence the participant’s decision to practice EINC amidst the pandemic.
METHODOLOGY:
For this phenomenological case study, online interviews with nine (9) participants were conducted using a 13-item questionnaire describing their experience. Thematic analysis using the inductive and semantic approach was conducted to identify the common themes or factors.
RESULTS:
Of the nine (9) participants, five (5) experienced EINC, while four (4) did not. The COVID-19 status and the choice to undergo Unang Yakap were not a causal relationship. Two main influences, mother-related factors, and hospital-related factors, were identified and were found to have weight in decision-making. The mother-related factors include prior knowledge and perception towards EINC, COVID-19 status, personal beliefs, and information from social media; while the hospital-related factors are hospital facilities, hospital protocols, and HCW-patient relationship.
CONCLUSION
By delineating the different factors that influence mothers’ decisions, this study allows for the identification of possible bottlenecks in the practice of EINC, as well as effective and efficient means to encourage its practice.
COVID-19
10.Success rate of helicobacter pylori eradication using vonoprazan-based triple therapy as first-line treatment at a tertiary hospital in Baguio City
Tristan John B. Guston, MD ; Maria Elizabeth T. Espiritu, MD
Philippine Journal of Internal Medicine 2023;61(2):36-44
Background:
Helicobacter pylori is acknowledged to cause chronic gastritis and peptic ulcer disease and is also implicated
in gastric carcinoma and B cell mucosa-associated lymphoid tissue (MALT) lymphoma development. It has infected at least
half of the world’s population. Proton Pump Inhibitors (PPIs) have been the conventional antacid of choice for H. pylori
eradication triple therapy, while vonoprazan is a novel drug of its class that was recently studied but is limited to an oral
form which makes it less feasible in cases of acute gastrointestinal bleeding. According to several systematic reviews and
meta-analyses, the vonoprazan-based triple therapy regimen for H. pylori eradication is a non-inferior treatment to
traditional PPI-based treatment when given in 1 week for patients having no active gastrointestinal bleeding. Likewise, a
safety profile has been established with its use, offering an alternative treatment option.
Objectives:
The research aims to identify the H. pylori eradication rate among H. pylori-positive patients who received a
vonoprazan-based triple therapy regimen as outpatients, describe their clinicodemographic profile, and identify potential
side effects associated with the treatment.
Methods:
This study utilized a cross-sectional study design in a single tertiary institution from January 2018 to December
2020. Descriptive and inferential statistics were used in data analysis. Frequency and percentage were utilized to determine
the success and failure rates of H. pylori eradication, describe the clinicodemographic profile of patients who underwent
vonoprazan-based triple therapy, and the potential side effects with treatment. The chi-square test of independence was
applied to assess the significant difference in the successful and failed eradication rates across the clinicodemographic
profile. A P-value of <0.05 was considered statistically significant, and statistical analyses were conducted using SPSS
version 20.0.
Results:
32 (91%) had successful H. pylori eradication, with the majority of them determined by a negative 13C-UBT result
(62.8%) and the rest with a negative H. pylori stool antigen test (28.6%). The majority of patients undergoing H. pylori
eradication using a vonoprazan-based regimen with documented successful eradication belonged to the 19 to 39 years
old group (50%), clerical support workers (40.63%), with a chief complaint of abdominal pain (46.88%), with no known co-
morbid illness (75%), and with endoscopic finding limited to antral gastritis alone (46.88%). This study described only two
documented side effects of treatment: diarrhea and abdominal pain (2.9%).
Conclusion
Vonoprazan-based triple therapy, given at 20 mg twice daily for 7 days, has shown a high H. pylori eradication
rate among hemodynamically stable patients, without active bleeding, and treated on an outpatient basis. There was a
significant difference in eradication success and failure across co-morbidities, with a higher success rate in those without
co-morbid illness. A high success rate was also seen in patients <40 years of age, with a single chief complaint, and with
antral gastritis as the sole endoscopic finding.
Helicobacter pylori


Result Analysis
Print
Save
E-mail