1.Mean Corpuscular volume in alcoholics.
Seog Woon KWON ; Seong Ho PARK ; Duk Lyul NA ; Sang Woon CHOI ; Han Ik CHO
Korean Journal of Clinical Pathology 1992;12(3):299-303
No abstract available.
Alcoholics*
;
Erythrocyte Indices*
;
Humans
2.Red Cell Distribution Width and Coronary Artery Calcification.
Sevket BALTA ; Ali Osman YILDIRIM ; Cengiz OZTURK
Korean Circulation Journal 2016;46(2):270-272
No abstract available.
Coronary Vessels*
;
Erythrocyte Indices*
3.Red cell distribution width and its association with Neonatal Bacteremia: A case-control study
Hashima P. Diamla ; Robert Dennis J. Garcia
Pediatric Infectious Disease Society of the Philippines Journal 2022;23(1):50-61
Background:
Bacteremia is a major cause of prolonged hospital stay and mortality in neonates and its early diagnosis remains a challenge to pediatricians. Red cell distribution width (RDW) is a component of a complete blood count test which is accessible and inexpensive and has been reported to be a possible diagnostic marker for neonatal bacteremia. This study determined the association of RDW with neonatal bacteremia in term and preterm neonates.
Methodology:
This is a retrospective case-control study of 26 bacteremic neonates as cases and 104 non-bacteremic neonates, either symptomatic or with risk factors for bacteremia, as controls. Included newborns were seen between January 1, 2010 to September 30, 2021. Laboratory data obtained were CBC, C-reactive protein and blood culture.
Results:
RDW values between bacteremic and non-bacteremic neonates were not significantly different. There was an association between RDW and neonatal bacteremia at an RDW level of > 16.1, where the likelihood of bacteremia was three times higher compared with lower RDW values. Significantly lower levels of hemoglobin, hematocrit, RBC count, WBC count, platelet count, MCH and MCHC, and a higher CRP level were seen among bacteremic neonates compared to those who were not. The median RDW for both term and preterm neonates was close to 16, with a narrow inter-quartile range at 1 and 2 for controls and cases, respectively. The range (minimum to maximum) of RDW values of bacteremic preterm neonates was more variable than those of term neonates. Using RDW to detect bacteremia, it had an equivocal discriminatory power or AUC of 0.6056. We found insufficient evidence to demonstrate a correlation between RDW and other CBC parameters, except for MCHC. For MCHC, the results suggest a very weak and indirect correlation.
Conclusion
RDW was not significantly different between bacteremic and non-bacteremic neonates, but there was a suggested association between RDW and bacteremia at an RDW level of > 16.1, at which level there was a 3-fold risk for bacteremia.
Erythrocyte Indices
;
Case-Control Studies
4.Increase of red blood cell's mean corpuscular volume in the elderly normal population of Korea.
Soo Jung JE ; Cheolwon SUH ; Hyun Sook CHI
Korean Journal of Hematology 1992;27(2):227-231
No abstract available.
Aged*
;
Erythrocyte Indices*
;
Humans
;
Korea*
5.Assessment of Bull's Mean and Exponentially Adjusted Moving Mean (EAMM) Using Selection of Expected Range in the Red Cell Indices.
Seung Min HONG ; Ha Young CHOI ; Jin IM ; Sook Jin JANG ; Dae Soo MOON ; Young Jin PARK
Korean Journal of Clinical Pathology 1998;18(3):299-305
BACKGROUND: Because moving means can be easily shiftable according to their crude data, we made a selective expected ranges to calculate the moving means. Bull's mean (exponential factor, P=0.50) and Exponentially Adjusted Moving Mean (EAMM, P=0.66) were assessed. we studied to determine appropriately expected range and exponential factor. METHODS: We made the target values from RBC indices being measured with H-2 hematology autoanalyzer from 800 patients and the expected range from red cell indices data of additional 600 patients. Both moving means using this expected ranges were calculated. The % difference of Bull's mean and EAMM was compared and total mean of (deltaBull's mean/deltaBatch mean) and (deltaEAMM/deltaBatch mean) was compared. RESULTS: The target values were MCV: 90.6 fL, MCH: 29.8 pg. MCHC: 32.8 g/dL. The expected ranges were within +/-6% of their target values. Among the 20 batches obtained from expected range, there were no above +/-3% difference of red cell indices in both moving means. The comparison between % difference of Bull's mean and that of EAMM showed no difference. Total mean of (deltaEAMM/deltaBatch mean) was higher than that of (deltaBull's mean/deltaBatch mean). CONCLUSIONS: The % difference results of Bull's mean and EAMM were basically similiar within the expected range but EAMM method was more sensitive than Bull's mean method under the aspect of specimen effects, so EAMM was more detectable than Bull's mean on the quality control of red cell indices.
Erythrocyte Indices*
;
Hematology
;
Humans
;
Quality Control
6.A Study on Red Cell Distribution Width of Iron Deficiency Anemia in Childhood.
Hong Ryang KIL ; Young Hun CHUNG
Journal of the Korean Pediatric Society 1988;31(10):1321-1327
No abstract available.
Anemia, Iron-Deficiency*
;
Erythrocyte Indices*
;
Iron*
8.A Study on the Normal Value of Red Blood Cell of Korean Primary School Children.
Journal of the Korean Pediatric Society 1981;24(8):743-751
This study was undertaken on 120 healthy primary school children (male 60, female 60), who live in a fishing village, Geo-Mun island, Chulla-Namdo, in order to investigate normal value of red blood cell. Ages of the children were ranged from six years to twelve years. The author cheked the number of red blood cell, hemoglobin level, hematcrit, mean corpuscular volume(MCV), mean corpuscular hemoglobin(MCH), and mean corpuscular hemoglobin concentration(MCHC). MCV, MCH, and MCHC were calulated by formula of Wintrobe. The results obtained were as follows; 1. The mean value of RBC count was 4,500,000/mm3(range : 3,470,000-5,850,000/mm3) 2. The mean value of hemoglobin level was 12.5gm/dl(range: 11.0~14.0gm/dl). 3. The mean value of hematcrit was 37.0%(range: 32~42%). 4. The mean value of MCV was 83.5 cub. micron(range 71.0~105.3 cub. micron.) 5. The mean value of MCH was 28.3rr(range: 22.2~39.7rr). 6. The mean value of MCHC was 33.8gm/100ml (range: 32.4~35.9/100 ml).
Child*
;
Erythrocyte Indices
;
Erythrocytes*
;
Female
;
Humans
;
Reference Values*
10.Comparing Biological Markers of Alcohol Dependence in the Patients of an Alcohol Counseling Center.
Jung Hyun BYUN ; Boung Chul LEE ; Byung Joo HAM ; Chan Seung CHUNG ; Mina HUR ; Jung Joon LEE ; Ihn Geun CHOI
Journal of the Korean Society of Biological Psychiatry 2006;13(4):273-278
OBJECTIVES: Biochemical markers can provide an objective evidence of heavy alcohol drinking. The purpose of this study was to compare and evaluate the usefulness of biological markers detecting alcohol dependence, such as mean corpuscular volume(MCV), gamma-glutamyl transferase(GGT), and carbohydrate-deficient transferrin(CDT) in the patients of an alcohol counseling center. METHODS: This study was done with 64 patients with alcohol dependence and 36 healthy subjects. Relative values(%) of CDT were determined in their sera with turbidimetric immunoassay(Bio-Rad %CDT assay, Axis-Shield ASA, Oslo, Norway), and were compared with conventional markers of alcohol consumption, GGT and MCV. RESULTS: Among the patients with alcohol dependence, 78.1% showed abnormal %CDT levels compared with GGT(61.9%) and MCV(20.7%). The areas under the receiver operating characteristic(ROC) curves(95% confidence interval) for %CDT, GGT, and MCV were 0.934(0.866-0.973), 0.871(0.789-0.930), and 0.575 (0.472-0.673), respectively. CONCLUSION: %CDT seems to be the most reliable biological marker for the detection and monitoring of alcohol consumption in the patients with alcohol dependence of the alcohol counseling center.
Alcohol Drinking
;
Alcoholism*
;
Biomarkers*
;
Counseling*
;
Erythrocyte Indices
;
gamma-Glutamyltransferase
;
Humans