Background: A water supply sufficiency and quality standard has been still important object of the priority issues of countries, regions as well as the Worldwide. In December, 2003, the General Assembly of the UN announced to worldwide a decade named as "Water for life" with duration of 2005 - 2015. Public Health Institute of Mongolia,2 Health Sciences University of Mongolia Background: A water supply sufficiency and quality standard has been still important object of the priority issues of countries, regions as well as the Worldwide. In December, 2003, the General Assembly of the UN announced to worldwide a decade named as "Water for life" with duration of 2005 - 2015. Ensure environmental sustainability objective 6.16 within MDGs of Mongolia proposed to decrease a share of inhabitants without safe drinking water, and a share of inhabitants not provided by an improved sanitation infrastructure, respectively. After Mongolia shifted to a market economy system, production rapidly developed, and rapid increasing of mining, population centralization in urban areas and use of the chemical elements were basic and necessary conditions to study an arsenic content in drinking water of Gobi provinces. Goal: To determine arsenic content in drinking water of Gobi provinces and provide a hygienic assessment. Materials and Methods: Research study designed by cross-section methods and analyzed one action data. In total of 62 soumsfrom five Gobi provinces (namely Gobi-Altai, Gobisumber, Dornogobi, Dundgobi, and Umnugobi) were selected as a research sites. Samples are taken according to the standard MNS ISO 5667-2:2001 from total of 142 deep drilled wells amongst 62 selected soums. According to the ISO-MNS 11885:2007 standard, arsenic content (As) were tested in the samples by using Optical Emission Spectrometer with brand name of Varian 720 -ESICP. Test analyses were assessed after comparison with the content level of arsenic in drinking water standard of Mongolia as coded MNS 900:2005 and the recommended levels stated in "Guidelines for drinking water quality", developed by the WHO. Results: Arsenic contents were presented 106 samples, represented 74.6 percent of the total samples from the 142 deep drilled wells in the selected sites of 62 soums among 5 Gobi provinces. In additionally, existing arsenic contents in 22 samples were 15.4 percent of the selected samples counted 1 to 6 times higher than the drinking water standard of Mongolia as coded MNS 900:2005 and the recommended levels stated in "WHO - Guidelines for drinking water quality". Total drinking water arsenic contents across the selected 5 Gobi provinces were statistical mean 0.0084 ± 0.0009 mg/l. Conclusion: 15.4 percent arsenic contents in drinking water in Gobi provinces were greater than the drinking water standard of Mongolia as coded MNS 900:2005 and the recommended levels stated in "WHO - Guidelines for drinking water quality".

Background: Last years increased the human and animal cases of anthrax. During 2000-2009 infected 197 livestock of them 73 cattles, 7 horses, 13 goats and 104 sheep and 10 human cases of anthrax at Khentii province. Goal: We are aimed to evaluate human and animal cases of anthrax which registered at Khentii province last 10 years.Materials and methods: Used for registration of veterinary report of 2000-2009, last 10 years report of human cases of CIDNF Khentii province. Analyzed the data, compared and evaluated the result of human and animal anthrax cases. Results: The Khentii province included at zone of middle risk, active foci by classification of anthrax risk foci (Tserendorj and et all, 2006). Totally 1148 livestock infected by anthrax during 2000-2009 in national level and of them 17.1% registered at Khentii province. Infected 10 patient during 2000-2009 occurred 12.7 % than national level. Most of patients 95.2% (16) infected by used the skin, meat with died from anthrax. The 4.8% (1) of all patients infected from soil which work at soil. All patients infected by bubonic form. Last 2007, 2008,2009 disinfected at soil and decreased the detection of cultures or positive results from soil.Conclusion: The high risk of human anthrax depends on most likely from animals and soils. Herders take more risks due to their job specialization. Male workers of working age groups are generally infected by anthrax in particular. Especially assistant workers in agriculture and mining sectors are extra vulnerable in anthrax. The new areas have been infected by the virus of human and animal anthraxes because of increases of animal movement from place to place. The reasons of animal movement are number of people working in commercial and hand operated gold mining, herders movement to another area for looking pasture (otor) and growing number of celebration activities (Batshireet, Norovlin soum in 2007).

BACKGROUND: Tuberculosis (TB) morbidity and mortality has been one of the pressing issues in the health sector of our country. In Mongolia, 2 people out of 1000 people developed tuberculosis annually, which leads to becoming one of the 7 countries with high TB morbidity among 37 countries of the Western Pacifi c Region.OBJECTIVE: The aim of the study is to have the baseline to understand and measure knowledge, attitudes and practices regarding tuberculosis among non-tuberculosis health care workers including family group practitioners, nurses and specialized doctors at the primary, secondary and tertiary health care level of Mongolia.MATERIALS AND METHOD: Cross-sectional descriptive qualitative study. Self-admitted questionnaire were performed for 572 health care workers. Total of 4 aimags/provinces and 3 districts were randomly selected. Selenge, Darkhan-Uul, and Khentii aimags are regions with high tuberculosis burden, Dornogobi and Orkhon aimags are with low Tuberculosis incidence and prevalence in 2008.Altogether 572 doctors and health professionals from selected health facilities were involved in survey questionnaire and 39.9% (228 people) of respondents were working at the primary level, 31.3% (179 people) in secondary level, and 28.8% (165 people) in the tertiary level health facility, respectively. Altogether 23 focus group discussions were organized, involving 130 people.RESULTS: Around 98.6% of respondents answered that TB is spread when infected person coughs and sneezes. However, one of every three respondents answered TB can be transmitted when sharing cups, dishes and other cooking utensils with the infected person, one in every ten people–shaking hands with the infected person, and one in every four people–through mother to child transmission. Such misconception is common among the health professionals, especially among nurses of the secondary and tertiary level health facilities. Around 47.6% or 272 people answered correctly that TB patients have symptoms such as coughing for 2 weeks and longer, develop sputum with blood traces, fever and sweating during night sleep, and loss of weight. However, there is some misunderstanding among the doctors and nurses such as there are skin rashes. When doctors and nurses where asked which form of TB is the infectious one, 86.9% answered correctly that TB with positive smear test is infectious. On assessing the knowledge, attitude and practice on TB treatment, about 93.4% of the respondents answered that treatment shall be done by anti-TB drugs and this result is equally strong among health professionals at all service delivery levels (p=0.075). However, there are some misconceptions among the nurses that TB patients should buy anti-TB drugs from the pharmacies, try traditional medicines and follow religious rituals. This should be paid further attention and issues covering TB should be included in their curriculum. Every second person knows the treatment continuation period of drug susceptible TB patient, which is relatively low knowledge level. According to survey results, every second person knows what DOTS stand for. In other words, 55.4% of the respondents identifi ed correctly what is DOTS, and 13.8% answered that it is a combination of anti-TB drugs, 3 .3% - as TB treatment method, 5.6% - as combination of TB reduction measures, and 2.2% answered that they don’t know.CONCLUSION: Many misunderstandings were found in the fi eld of transmission, BCG vaccination, treatment and anti-TB drugs. There is a need to provide training for non-TB medical doctors and nurses.

Introduction: One of the main ingredients of Anar-5 tablets is Piper longium L. Piperine alkaloids are the main active ingredients of the Piper longum and have anti-inflammatory, antioxidant and gastric protection properties.In the framework of the standardization study of Anar-5 tablets, a method was developed to determine the content of piperine in highly perpormance liquid chromatography, and then it was sought to include it in the method of analysis of Anar-5 drugs. Goal: Quantitative determination of piperine in Anar-5 tablets and validate the method Material and Methods: The research was conducted in the Chemistry and Chemical Technology Laboratory of the Research Center of the Institute of Traditional Medicine and Technology. And Anar-5 tablets (serial number 04012020) that are produced for experimental were used in the research. The standard substance, piperine alkaloids, was purchased from Green Chemistry.Purification of HPLC (organic solvent methanol, 99.9%, distilled water) was used. The EX 1600 HP/ PUMP high-performance liquid chromatography instrument (column Arcus EP+-C18, 5µm, 4.6x250 mm) and the organic solvent filter 0.45 μm syringe filter were used. The methodology related to this research was discussed and approved at the online meeting of the Ethics Committee of the Academy of Sciences on January 26, 2021. SPSS 16 software was used to statistically program the survey results. Results : According to the above method, the retention time of the standard piperine is 10.38± 0.02 minutes, and the retention time of the piperine in Anar-5 tablets is 10.42±0.033 minutes. Relative velocity deviation RSD 1.077%, accuracy 0.65446±0.0068mg, stability 0.61298±0.013mg, capture time 10.42±0.033 minutes, relative standard deviation RSD≤2%, specificity 10.35 minutes, The equation of a line constructed with a standard curve is y=43360x-33587 and the correlation coefficient R2=0.9989. The piperine content of Anar-5 tablets was determined to be 0.61298±0.013 mg. The LOD and LOQ for piperine were in 2.268 μg/ml and 6.873 μg/ml, respectively. Conclusion The content of piperine in Anar-5 tablets can be determined by the HPLC method, and the appropriate conditions for this method have been established. The HPLC method is unique, accurate, linear, and stable, and meets ICH Q2 (R1) guideline criteria.