Eighty cases of intrauterine adhesions who received adhesion separation technique were divided into two groups equally. The control group was placed intrauterine device and ballon catheter in intrauterine,and received o-ral female estrogen cycle treatment. The test group with the same treatment was added growth hormone treatment. Three months later,all of the patients were checked the hysteroscopy and intrauterine device was took out, also the uterine cavity form,and follow-up recovery of endometrial and menses were evaluated. Then it showed:①Endome-trial thickness increased by an average of (1.73±0.83) mm in the test group,while the control group average in-creased by (1.10±0.66) mm. The difference was statistically significant (t=3.73,P<0.01).② The re-adhe-sion rate was 45.0% in the control group,while it was 32.5% in the test group,respectively. The difference was not statistically significant. ③ The difference of mensual recovery between both groups was not statistical significant. Therefore growth hormone can promote the growth of endometrium of intrauterine adhesions after resection of adhe-sions.

Purpose To investigate the expression of estrogen receptor ( ER) and progesterone receptor ( PR) in endometrial tissue in patients with intrauterine adhesion ( IUA) and their clinical significance. Methods Two experimental methods, immunohistochemical MaxVision two step method and real-time fluorescencequantitative PCR ( qRT-PCR) , were used for detection of ER and PR in endome-trial tissue both in group IUA ( study group) and non IUA group ( control group) . Results MaxVision immunohistochemical method showed that ER protein expression in the study group (3. 52 ± 0. 71) was significantly higher than that (2. 75 ± 1. 00) in the control group (P=0. 01), ER mRNA expression by qRT-PCR was also significantly higher in the study group (1. 59 ± 0. 26) than that (1. 00 ± 0. 19) in the control group (P=0. 00). The immunohistochemical detection of showed that PR protein expression in the study group (3.26 ±0.70) had no significant different from that (3.58 ±0.28) in the control group (P=0.12), qRT-PCR also showed that ER mRNA in the study group (1.15 ±0.21) had no significantly different from that (1.00 ±0.31) in the control group (P=0. 21 ) . Immunohistochemical expression of ER and PR proteins showed a significant difference between the endometrial glands and en-dometrial stroma (χ2 =5. 797, P=0. 016,χ2 =4. 857, P=0. 027). Conclusion The expression of ER in endometrial tissue in the study group is higher than that in the control group, but the expression of PR has no different between the two groups, ER and PR pro-teins expression are higher in endometrial glands than that in endometrial stroma. These provide a theoretical reference for clinical use of estrogen and progesterone to IUA patients.