Objective To measure 222Rn and 220Rn concentrations in the underground non-uranium mines in Shandong Province,and to estimate the annual effective dose to the miners.Methods Concentrations of 222Rn and 220Rn in selected gold,iron,coal and clay mines were determined by passive time-integrating detectors with CR-39.Activity concentrations of 226Ra,232Th and 40K were determined using gamma spectrometry equipped with HPGe detector.Results The average concentrations of 220Rn in the gold,iron,coal and clay mines were estimated to be 1200,280,120 and 40 Bq/m3,respectively.The activity concentrations of 226Ra,232Th,40K in the ores for gold,iron,coal and clay mines ranged the same as the soil in China.The annual effective dose due to radon exposure in gold and iron mine was 7.70 mSv and 1.74 mSv,respectively.The annual doses received by miners in the coal and clay mines were lower than 1 mSv.Conclusions Underground miners in some gold and iron mines should be treated as workers occupationally exposed to ionizing radiation.The measurement such as increasing ventilation should be implemented to reduce underground radon concentration in these mines.

Objective:To investigate the clinical value of serum levels of secreted frizzled related protein 1 (SFRP1), D-dimer to fibrinogen ratio (DFR), Irisin in predicting prognosis in patients with acute exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) complicated with pulmonary embolism.Methods:Retrospectively AECOPD patients with concurrent pulmonary embolism admitted to the Wuhan No.1 Hospital from January 2021 to December 2023were selected, and divided into a survival group of 50 cases and a death group of 10 cases based on their survival outcomes during hospitalization. Comparing the general clinical data and serum levels of SFRP1, DFR, and Irisin between two groups of patients, a logistic regression model was used to analyze the correlation between the course of AECOPD, SFRP1, DFR, and Irisin levels and adverse prognosis in AECOPD patients with pulmonary embolism. Receiver operating characteristic (ROC) curves were plotted to analyze the value of SFRP1, DFR, and Irisin in predicting adverse prognosis in AECOPD patients with pulmonary embolism.Results:There was a statistically significant difference in the duration of AECOPD between the two groups of patients ( P<0.05). The differences in serum SFRP1, DFR, and Irisin levels between the two groups of patients were statistically significant (all P<0.05). The results of logistic regression analysis showed that SFRP1, DFR, and Irisin ( OR=1.022, 4.991, 0.719) were influencing factors on the prognosis of AECOPD patients with pulmonary embolism (all P<0.05). The ROC curve showed that the area under the curve (AUC) of SFRP1, DFR, and Irisin for predicting adverse prognostic outcomes in AECOPD patients with pulmonary embolism was 0.844, 0.920, and 0.842, respectively. Conclusions:SFRP1, DFR, and Irisin are influencing factors for poor prognosis in AECOPD patients with pulmonary embolism, and have high value in predicting the prognosis of AECOPD patients with pulmonary embolism.