1.Impulse control behaviours in a Malaysian Parkinson’s disease population
Shahrul Azmin ; Eng Liang Tan ; Nik Jaafar Nik Ruzyanei ; Zakaria Hazli ; Azmawati Mohammed Nawi ; Zhe Kang Law ; Remli Rabani ; Wan Yahya Nafisah ; Ramesh Sahathevan ; Hui Jan Tan ; Nur Fadhlina M. Pakarul Razy ; Nor Azian Abdul Murad ; King-Hwa Ling ; Mohamed Ibrahim
Neurology Asia 2016;21(2):137-143
Background: Impulse control behaviours are repetitive and excessive activities that may be subsyndromal
and not fulfil the criteria for impulse control disorder. These activities have potential to
negatively impact on the daily lives of sufferers. We conducted a study to investigate the prevalence
of impulse control behaviours and its associated features in Parkinson’s disease in our population.
Methods: We conducted a prospective cross-sectional study on consecutive patients attending neurology
clinic. Inclusion criteria include idiopathic Parkinson’s disease patients with Hoehn & Yahr stage I-IV.
Eighty patients were enrolled and screened for impulse control behaviours using the Questionnaire
for Impulsive-Compulsive Disorder for Parkinson’s disease (QUIP). Results: Prevalence of impulse
control behaviours among our cohort was 11.3%; the features significantly associated with it were
higher level of education (p=0.02), advanced stage of disease (p=0.03) and higher levodopa dosage
(p= 0.01). The commonest impulse control behaviour in our cohort was compulsive medication use
(7.5%), followed by hobbyism (6.3%), hypersexuality (5%), compulsive buying (3.75%), punding
(2.5%), walkabout (2.5%), compulsive eating (1.25%) and pathological gambling (1.3%).
Conclusions: There is an association between impulse control behaviour and higher levodopa dosage
in a study on patients with Parkinson’s disease in Malaysia. We also found a low prevalence of
pathological gambling as compared to studies performed in the West.
Disruptive, Impulse Control, and Conduct Disorders
;
Parkinson Disease
2.Current Status and Growth of Nuclear Theranostics in Singapore
Hian Liang HUANG ; Aaron Kian Ti TONG ; Sue Ping THANG ; Sean Xuexian YAN ; Winnie Wing Chuen LAM ; Kelvin Siu Hoong LOKE ; Charlene Yu Lin TANG ; Lenith Tai Jit CHENG ; Gideon Su Kai OOI ; Han Chung LOW ; Butch Maulion MAGSOMBOL ; Wei Ying THAM ; Charles Xian Yang GOH ; Colin Jingxian TAN ; Yiu Ming KHOR ; Sumbul ZAHEER ; Pushan BHARADWAJ ; Wanying XIE ; David Chee Eng NG
Korean Journal of Nuclear Medicine 2019;53(2):96-101
The concept of theranostics, where individual patient-level biological information is used to choose the optimal therapy for that individual, has become more popular in the modern era of ‘personalised’ medicine. With the growth of theranostics, nuclear medicine as a specialty is uniquely poised to grow along with the ever-increasing number of concepts combining imaging and therapy. This special report summarises the status and growth of Theranostic Nuclear Medicine in Singapore.We will cover our experience with the use of radioiodine, radioiodinated metaiodobenzylguanidine, peptide receptor radionuclide therapy, prostate specific membrane antigen radioligand therapy, radium-223 and yttrium-90 selective internal radiation therapy.We also include a section on our radiopharmacy laboratory, crucial to our implementation of theranostic principles. Radionuclide theranostics has seen tremendous growth and we hope to be able to grow alongside to continue to serve the patients in Singapore and in the region.
Hope
;
Humans
;
Lutetium
;
Membranes
;
Nuclear Medicine
;
Prostate
;
Radium
;
Receptors, Peptide
;
Singapore
;
Theranostic Nanomedicine
;
Yttrium
3.Current Status and Growth of Nuclear Theranostics in Singapore
Hian Liang HUANG ; Aaron Kian Ti TONG ; Sue Ping THANG ; Sean Xuexian YAN ; Winnie Wing Chuen LAM ; Kelvin Siu Hoong LOKE ; Charlene Yu Lin TANG ; Lenith Tai Jit CHENG ; Gideon Su Kai OOI ; Han Chung LOW ; Butch Maulion MAGSOMBOL ; Wei Ying THAM ; Charles Xian Yang GOH ; Colin Jingxian TAN ; Yiu Ming KHOR ; Sumbul ZAHEER ; Pushan BHARADWAJ ; Wanying XIE ; David Chee Eng NG
Korean Journal of Nuclear Medicine 2019;53(2):96-101
The concept of theranostics, where individual patient-level biological information is used to choose the optimal therapy for that individual, has become more popular in the modern era of ‘personalised’ medicine. With the growth of theranostics, nuclear medicine as a specialty is uniquely poised to grow along with the ever-increasing number of concepts combining imaging and therapy. This special report summarises the status and growth of Theranostic Nuclear Medicine in Singapore.We will cover our experience with the use of radioiodine, radioiodinated metaiodobenzylguanidine, peptide receptor radionuclide therapy, prostate specific membrane antigen radioligand therapy, radium-223 and yttrium-90 selective internal radiation therapy.We also include a section on our radiopharmacy laboratory, crucial to our implementation of theranostic principles. Radionuclide theranostics has seen tremendous growth and we hope to be able to grow alongside to continue to serve the patients in Singapore and in the region.
4.SingHealth Radiology Archives pictorial essay Part 1: cardiovascular, respiratory and neurological cases.
Mark Bangwei TAN ; Kim Ping TAN ; Joey Chan Yiing BEH ; Eugenie Yi Kar CHAN ; Kenneth Fu Wen CHIN ; Zong Yi CHIN ; Wei Ming CHUA ; Aaron Wei-Loong CHONG ; Gary Tianyu GU ; Wenlu HOU ; Anna Chooi Yan LAI ; Rebekah Zhuyi LEE ; Perry Jia Ren LIEW ; May Yi Shan LIM ; Joshua Li Liang LIM ; Zehao TAN ; Eelin TAN ; Grace Siew Lim TAN ; Timothy Shao Ern TAN ; Eu Jin TAN ; Alexander Sheng Ming TAN ; Yet Yen YAN ; Winston Eng Hoe LIM
Singapore medical journal 2020;61(12):633-640
The Singapore Health Services cluster (SingHealth) radiology film archives are a valuable repository of local radiological cases dating back to the 1950s. Some of the cases in the archives are of historical medical interest, i.e. cerebral angiography in the workup of patients with hemiplegia. Other cases are of historical social interest, being conditions seen during earlier stages of Singapore's development, i.e. bound feet. The archives form a unique portal into the development of local radiology as well as the national development of Singapore. A selection from the archives is published in 2020 in commemoration of the 20th anniversary of the formation of SingHealth, the 55th National Day of Singapore, and the 125th anniversary of the International Day of Radiology. This pictorial essay comprises cardiovascular, respiratory and neurological cases from the archives.
5.SingHealth Radiology Archives pictorial essay Part 2: gastroenterology, musculoskeletal, and obstetrics and gynaecology cases.
Mark Bangwei TAN ; Kim Ping TAN ; Joey Chan Yiing BEH ; Eugenie Yi Kar CHAN ; Kenneth Fu Wen CHIN ; Zong Yi CHIN ; Wei Ming CHUA ; Aaron Wei-Loong CHONG ; Gary Tianyu GU ; Wenlu HOU ; Anna Chooi Yan LAI ; Rebekah Zhuyi LEE ; Perry Jia Ren LIEW ; May Yi Shan LIM ; Joshua Li Liang LIM ; Zehao TAN ; Eelin TAN ; Grace Siew Lim TAN ; Timothy Shao Ern TAN ; Eu Jin TAN ; Alexander Sheng Ming TAN ; Yet Yen YAN ; Winston Eng Hoe LIM
Singapore medical journal 2021;62(1):8-15
The Singapore Health Services cluster (SingHealth) radiology film archives are a valuable repository of local radiological cases dating back to the 1950s. Some of the cases in the archives are of historical medical interest, i.e. cerebral angiography in the workup of patients with hemiplegia. Other cases are of historical social interest, being conditions seen during earlier stages of Singapore's development, i.e. bound feet. The archives form a unique portal into the development of local radiology as well as the national development of Singapore. A selection from the archives is published in commemoration of the International Day of Radiology in 2020, as well as the 200th anniversary of the Singapore General Hospital in 2021. This pictorial essay comprises gastroenterology, musculoskeletal and obstetrics and gynaecology cases from the archives.