1.Follow-up Studies on Balneotherapeutic Effects on the Vibration Dissease in Hokkaido
The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine 1978;42(1-2):36-38
Balneotherapy was applied to 15 male cases of vibration disorder for four weeks, whereby examinations were made to judge their disorder of peripheral circulating and nervaus functions at the time of entering and leaving hospital. Results of the examinations disclosed an improving trend concerning skin temperature of fingers, score of nail press test, vibration sensation and pain sensation, which evidently suggests that this therapy is useful in curing of the disorder of peripheral circulation and peripheral nerves.
Meanwhile each of the examinations of skin temperature at the immersion test of one hand, score of nail press test and vibration sensation provides a useful measure for the judgement of remedial values.
2.Studies on Moxibustion in Acrylamide Peripheral Neuropathy (report 1)
Masako OKAZAKI ; Yoshiko SAKURAI ; Hideki SAITO ; Eiji FURUYA ; Koji SAKAMOTO
Journal of the Japan Society of Acupuncture and Moxibustion 1984;33(3):221-228
The establishment of experimental peripheral neuropathy and effect of moxibustion on it have been studied using male S. D. rats. To determine the condition of experimental peripheral neuropathy, rats were fed on the solution of acrylamide in the concentration of 100, 200, 300, 400 and 500p.p.m. The body weight decreased dependently on its concentration and the behavior in rats was also detriorated. Especially, ataxia, hindlimb weakness and muscle wasting in rats were remarkably observed.
The effect of moxibustion has been studied on the rats which fed on the 400p.p.m. acrylamide solution. The method of moxibustion is followes; 25mg of moxa was divided into 10 cones and they were treated by each 5 cones on right and left B-18, B-25 and G-34, respectively. The treatment of moxibustion was 6 times in 3 ones a week for 13 days.
As a results, after 12-13 days, moxibustion treated rats showed to improve the deterioration of behavior and muscle wasting induced by acrylamide. Especially, B-25 treated rats showed the improvement of weight in anterior tibial, gastrocnemius and soleus muscle. On the other hand, steadiness on slope was decreased by acrylamide feeding and decrease of the steadiness was not improved by the treatment of moxibustion.
It is suggested that the sutable stimulation of moxibustion improved the deterioration of behavior and muscle waste on the acrylamide induced peripheral neuropathy in rats.
3.Studies on Moxibustion in Acrylamide Peripheral Neuropathy (report 2)
Masako OKAZAKI ; Eiji FURUYA ; Yoshiko SAKURAI ; Hideki SAITO ; Koji SAKAMOTO
Journal of the Japan Society of Acupuncture and Moxibustion 1984;33(3):229-237
Morphological changes of sciatic and tivial nerves have been observed microscopically and cholinesterase activities of anterior tibial, gastrocnemius and soleus muscles have been examined by the biochemical determination and histochemical method. 25mg of moxa/body (3 times a week, x6) were treated on the acupuncture point, B-18, B-25 and G-34 in acrylamide neuropathy rats.
After 400p.p.m. acrylamide treatment, the degeneration of peripheral nerves with myelin ovoids and foldes, and shrunken myelinated axons were observed. These lesions were advanced in the tibial nerve than in the sciatic nerve. In B-25 and B-18 moxibustion rats, good results were obtained to decrease myelin degeneration in peripheral nerves, but the lesions were advanced in G-34 rats than in acrylamide ones.
In the acrylamide rats, no change of muscle cholinesterase activity was found except the increase in the enzyme activity in the homogenate of anterior tibial muscle. In the gastrocnemius muscle of moxibustion treated rats, the microsomal fraction which contained much more sarcoplasmic reticulum showed high cholinesterse activity. And the activity per muscle protein showed various changes.
It showed that the stimulation of moxibustion had a mild effect to recover the experimental peripheral neuropathy induced by 400p.p.m. acrylamide because of morphological changes of sciatic and tibial nerves and weight of skeletal muscles.
4.What Are Core Clinical Competencies for Medical Residents?: A Qualitative Study
Kei-ichiro KITA ; Eiji SHINNO ; Koji OHZAWA ; Seiji SAITO ; Akiharu WATANABE
Medical Education 2004;35(1):25-31
To clarify the core competencies developed through postgraduate clinical training, we analyzed the conditions of our residency program with qualitative research methods. Seven residents (6 first-year residents and 1 second-year resident) answered a questionnaire and underwent semistructured interviews about postgraduate training. We also worked with the residents as “participant observers” of the treatment team. We found that residents often had trouble formulating diagnostic/treatment plans and tended to rely excessively on laboratory data to make decisions. We attribute these problems to a lack of practice in questioning expectations. We hypothesized that mitate-ryoku, the ability to describe the course of a patient's illness, is an extremely important clinical competency. According to the hypothesis, we tried to listen to the residents' description and to discuss it logically as colleagues. The residents described the patients expected condition over the next few days, considering both data and information they obtained from interviews and physical examinations. They adapted their ideas through logical discussion and were thus able to make acceptable decisions by themselves.
5.An Integrated High School-University Lecture Program in Basic Medical Science
Yoji NAGASHIMA ; Yukio KATOUNO ; Takamasa SAITO ; Hideki KANEKO ; Ichiro AOKI ; Hitoshi KITAMURA ; Rieko IJIRI ; Eiji GOTO
Medical Education 2005;36(2):101-106
Integrated lecture programs for high school students involving university teaching staff have recently become popular. Here, we report on such a program involving lectures on tumor pathology attended by 110 high school students at the Yokohama City University School of Medicine. Two weeks before the lectures at our university, the students were given a 45-minute introductory lecture by a teacher at their school. The 1-day course at our university comprised an overview lecture by the author (40 minutes), light-microscopic observation of histologic specimens of normal and tumor tissues (50 minutes), and a summary with an introduction to diagnostic pathology (20 minutes). During light-microscopic observation, medical students served as teaching assistants. The high school students were given handouts of microscopic
6.Comparative Analysis of Faculty Development in Japanese Medical Schools from 2003 through 2005
Nobuo NARA ; Masaaki ITO ; Eiji GOTOH ; Nobuhiko SAITO ; Yujiro TANAKA ; Masahiro TANABE ; Osamu FUKUSHIMA ; Saburo HORIUCHI
Medical Education 2007;38(4):275-278
1) The faculty development at each medical school from 2003 through 2005 was analysed.
2) The major themes in faculty development were problem based learning, tutorial, computer based testing, and clinical training.
3) Faculty development is considered an effective way to enhance the contributions of faculty members to medical education.
7.Problems in Preparing Multiple Choice Questions for Computer-based Testing Used in the Nationwide Common Examination before Clinical Clerkships
Nobuo NARA ; Yoshio NITTA ; Tatsuki ISHIDA ; Osamu FUKUSHIMA ; Eiji GOTOH ; Nobuhiko SAITO ; Yasuichiro FUKUDA ; Fumimaro TAKAKU ; Tatsuo SATO
Medical Education 2003;34(5):335-341
In 2002, Japanese medical students began computer-based testing (CBT) to assess their basic and clinical medical knowledge, based on the model core-curriculum, before starting clinical clerkships. Of 9, 919 multiple choice questions submitted by 80 medical schools, 2, 791 were used for CBT and 7, 128 were rejected. To improve the quality of future CBT, we analyzed why questions were rejected. The most commons reasons were difficulty, length, and inappropriate choice of answers. A training course may be needed to improve the ability of medical school staff to devise questions.
8.Effect of Workshops for Preparing Multiple-Choice Questions for Computer-Based Testing Used in the Nationwide Common Examination Before Clinical Clerkships
Nobuo NARA ; Nobuhiko SAITO ; Shu KURAMOTO ; Eiji GOTOH ; Hiroaki NAKAJIMA ; Osamu FUKUSIMA ; Saburo HORIUCHI ; Toshimasa YOSHIOKA ; Yoshio NITTA ; Tatsuki ISHIDA ; Takeshi ASO ; Yasuichiro FUKUDA ; Fumimaro TAKAKU
Medical Education 2005;36(1):11-16
Computer-based testing (CBT) has been used in Japan since 2002 to assess medical students' basic and clinical medical knowledge, based on the model core-curriculum, before they start clinical clerkships. For effective CBT, multiplechoice questions must accurately assess the knowledge of students. Questions for CBT are submitted by all medical schools in Japan. However, only 40% of questions are chosen for CBT and used at random; the other 60% of questions are rejected because of poor quality. Toimprove the ability of medical staff to devise questions, workshops were held at 30 medical schools. The acceptance rate of questions from schools where workshops were held was significantly increased. The workshops were extremely effbctive for improving the quality of questions.
9.Diagnosis of Myocardial Viability by Fluorodeoxyglucose Distribution at the Border Zone of a Low Uptake Region.
Eiji TOYOTA ; Teruki SONE ; Kunihiko YOSHIKAWA ; Hiroaki MIMURA ; Akihiro HAYASHIDA ; Nozomi WADA ; Kikuko OBASE ; Koichiro IMAI ; Ken SAITO ; Tomoko MAEHAMA ; Masao FUKUNAGA ; Kiyoshi YOSHIDA
Yonsei Medical Journal 2010;51(2):178-186
PURPOSE: In cardiac 2-[F-18]fluoro-2-deoxy-D-glucose (FDG)-positron emission tomography (PET) examination, interpretation of myocardial viability in the low uptake region (LUR) has been difficult without additional perfusion imaging. We evaluated distribution patterns of FDG at the border zone of the LUR in the cardiac FDG-PET and established a novel parameter for diagnosing myocardial viability and for discriminating the LUR of normal variants. MATERIALS AND METHODS: Cardiac FDG-PET was performed in patients with a myocardial ischemic event (n = 22) and in healthy volunteers (n = 22). Whether the myocardium was not a viable myocardium (not-VM) or an ischemic but viable myocardium (isch-VM) was defined by an echocardiogram under a low dose of dobutamine infusion as the gold standard. FDG images were displayed as gray scaled-bull's eye mappings. FDG-plot profiles for LUR (= true ischemic region in the patients or normal variant region in healthy subjects) were calculated. Maximal values of FDG change at the LUR border zone (a steepness index; S(max) scale/pixel) were compared among not-VM, isch-VM, and normal myocardium. RESULTS: S(max) was significantly higher for n-VM compared to those with isch-VM or normal myocardium (ANOVA). A cut-off value of 0.30 in Smax demonstrated 100% sensitivity and 83% specificity for diagnosing n-VM and isch-VM. S(max) less than 0.23 discriminated LUR in normal myocardium from the LUR in patients with both n-VM and isch-VM with a 94% sensitivity and a 93% specificity. CONCLUSION: S(max) of the LUR in cardiac FDG-PET is a simple and useful parameter to diagnose n-VM and isch-VM, as well as to discriminate thr LUR of normal variants.
Aged
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Aged, 80 and over
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Echocardiography
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Female
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Fluorodeoxyglucose F18/*metabolism
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Humans
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Male
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Middle Aged
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Myocardial Infarction/metabolism/pathology
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Myocardium/*metabolism/*pathology
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Positron-Emission Tomography
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Young Adult
10.Design and fabrication of scaffolds for anatomic bone reconstruction.
Scott J Hollister ; Chia-Ying Lin ; Cheng-Yu Lin ; Rachel D Schek ; Juan M Taboas ; Colleen L Flanagan ; Eiji Saito ; Jessica M Williams ; Suman Das ; Tobias Wirtz ; Paul H Krebsbach
The Medical journal of Malaysia 2004;59 Suppl F():131-2