The afferent connections of the lateral hypothalamic nucleus in the rat werestudied with retrograde horseradish peroxidase(HRP)method using microinjection andmicroelectrophoretic technique.The microinjection syringe needle or microelectrophoretic pipette was insertedvertically into the brain or in inclined direction through the cerebellum.The results were as follows:Following HRP introduced into the lateral hypothalamic nucleus,labeled neuronswere found in the anterior hypothalamic nucleus,the paraventricular nucleus,thedorsal raphe nucleus,the locus coeruleus and substantia grisea periventricularis inall cases.In most cases,labeled cells were also observed within the lateral septal nucleus,the interstitial nucleus of stria terminalis,the medial preoptic nucleus,the lateralpreoptic nucleus,the supraoptic nucleus,the ventromedial hypothalamic nucleus,themedial and central amygdaloid nuclei,the nucleus reunius,the interpeduncular nuc-leus,the nucleus parabrachialis dorsalis,the nucleus parabrachialis ventralis,and thenucleus tractus solitanii.In a few cases,retrograde labeling of neurons was observed within the medialseptal nucleus,pars medialis of the nucleus medialis thalami,the supramammilarynucleus and nucleus raphe medianus.In certain cases,a small number of cells could be found in the dorsal tegmentalnucleus of Gudden and the nucleus dorsalis nervi vagi.Among those nuclei,the locus coeruleus,the supraoptic nucleus,the paraventri-cular nucleus and the dorsal parabrachial nucleus were labeled bilaterally.

Breast Neoplasms ; metabolism ; therapy ; Carcinoma, Ductal, Breast ; metabolism ; therapy ; Female ; Humans ; Immunohistochemistry ; Ki-67 Antigen ; metabolism ; Prognosis ; Receptor, ErbB-2 ; metabolism ; Receptors, Estrogen ; metabolism ; Receptors, Progesterone ; metabolism

No Abstract Available.
Growth Hormone* ; Signal Transduction*

Cytochrome P-450 CYP2E1 ; metabolism ; Fatty Liver, Alcoholic ; enzymology ; pathology ; Liver ; enzymology

Adult ; Aged ; Amyloidosis ; metabolism ; pathology ; Biopsy ; Female ; Humans ; Immunoglobulin Light-chain Amyloidosis ; Immunoglobulin kappa-Chains ; metabolism ; Immunoglobulin lambda-Chains ; metabolism ; Intestinal Mucosa ; pathology ; ultrastructure ; Kidney ; metabolism ; pathology ; ultrastructure ; Kidney Diseases ; metabolism ; pathology ; Male ; Middle Aged ; Rectum ; pathology ; ultrastructure ; Retrospective Studies

Biomedical Research ; trends ; Female ; Humans ; Hydatidiform Mole ; diagnosis ; genetics ; Pregnancy ; Uterine Neoplasms ; diagnosis

Biomarkers, Tumor ; analysis ; Humans ; Male ; MicroRNAs ; analysis ; Prognosis ; Prostatic Neoplasms ; chemistry ; genetics

Objective: To observe the efficacy of needling the Xi-Cleft points of yang meridians plus topical surrounding needling and pregabalin in treating postherpetic neuralgia (PHN) affecting the head and face and its influence on quality of life (QOL). Methods: Eighty patients with PHN affecting the head and face were randomized into an acupuncture-medication group and a Western medication group by their visiting sequence, with 40 cases in each group. The Western medication group took pregabalin capsules orally, 75 mg each time, twice a day. The dosage could increase to 150 mg each time and twice a day within 1 week based on the efficacy and tolerance. The treatment lasted for 5 weeks. The acupuncture-medication group was given additional surrounding needling at the herpes zoster on the head and face, and Xi-Cleft points of yang meridians were chosen according to the affected area for acupuncture, once every other day, for 5 weeks in total. Results: Prior to treatment, there were no significant differences in the visual analog scale (VAS) and QOL scores between the two groups (both P>0.05). After treatment, VAS and QOL scores dropped significantly in both groups (all P<0.01), and were significantly lower in the acupuncture-medication group than in the Western medication group (both P<0.01). The total effective rate was 67.5％ in the Western medication group, versus 92.5％ in the acupuncture-medication group, and the between-group difference was statistically significant (P<0.05). Conclusion: Based on oral administration of pregabalin, needling the Xi-Cleft points of yang meridians and topical surrounding needling can reduce PHN, notably improve patients' QOL, and produce more significant efficacy than oral administration of pregabalin alone.

Adenocarcinoma, Mucinous ; pathology ; Antigens, CD34 ; metabolism ; Breast ; metabolism ; pathology ; surgery ; Breast Diseases ; metabolism ; pathology ; surgery ; Breast Neoplasms ; pathology ; Diagnosis, Differential ; Female ; Fibroadenoma ; pathology ; Follow-Up Studies ; Humans ; Mastectomy ; Middle Aged ; Mucinoses ; metabolism ; pathology ; surgery ; Mucocele ; pathology ; S100 Proteins ; metabolism ; Vimentin ; metabolism

Actins ; metabolism ; Adrenal Gland Neoplasms ; diagnostic imaging ; metabolism ; pathology ; surgery ; Desmin ; metabolism ; Diagnosis, Differential ; Female ; Humans ; Immunohistochemistry ; Leiomyosarcoma ; diagnostic imaging ; metabolism ; pathology ; surgery ; Middle Aged ; Neoplasm Recurrence, Local ; surgery ; Reoperation ; Tomography, X-Ray Computed ; Vimentin ; metabolism