AIM: To evaluate the comfort and visual performance of Rose K2 soft contact lenses in patients with keratoconus.METHODS: Fifty eyes of 50 participants were included in this cross-sectional study.Each participant received a full ophthalmologic examination involving refraction,uncorrected visual acuity (UCVA),best spectacle corrected visual acuity (BCVA),slit-lamp biomicroscopy-fundoscopy,break-up time (BUT),corneal topography,and contrast sensitivity.After contact lens was fitted best contact lens corrected visual acuity (BCLCVA),contrast sensitivity,and comfort rating via visual analogue scales (VAS) were performed.RESULTS: The mean age was 26.2±6.0 (range: 16 to 39)y.The mean logMAR UCVA,BCVA,and BCLCVA with Rose K2 soft (in order) were 0.61±0.37 (range: 0.15-1.3),0.42±0.32 (range: 0-1.3),and 0.18±0.20 (range: 0-1.3).There were significant increases in visual acuities with contact lenses (P < 0.05).The mean contrast sensitivity scores were significantly better with both contact lens in mesopic and photopic conditions (P <0.05).The mean VAS score was 8.02±1.64 (range: 5-10) for Rose K2 soft.CONCLUSION: Rose K2 soft contact lens can improve visual acuity,contrast sensitivity with comfort in patients with keratoconus.