Objective To study the reconstruction of lip defects by using lingual membrane flaps. Methods 11 cases were presented, whose lip defects were extensively or partially. According to the size of defects, bilateral and lateral lingual membrane flaps were transfered to cover the defects to rebuild the lip contour, and then the posteriors were cut 2 weeks later. The repair of lip defects were done after the cover of region outside of lip in 4 patients who had composite defects. 4 patients underwent bilateral lingual membrane flap for repair of lip defects over 1/2 width of lip. 7 patients whose lip defects were less than 1/2 width of lip underwent lateral lingual membrane flap for repair. Results all the flaps were survival. The contour, color and function of lips were reconstructed well. The feeling, taste and movement of the tongue were normal. Conclusion Using lingual membrane flap to close the large defect of lip requires only one operation, especially in the defect repair with bilateral lingual membrane flaps. The flaps can not only rebuild the lip color and contour, but also remain enough tongue papilla in order to ensure the tongue taste after the operation. The excision in the tongue is hidden and tongue's function and contour can be little affected.