Objective To study the change of the level of serum cytokines in patients with epilepsy after cerebral infarction.Methods The levels of serum interleukin(IL)-2,IL-6 and tumor necrosis factor-?(TNF-?) in 87 patients with epilepsy after cerebral infarction(epilepsy group) and 75 normal controls(NC group) were measured by radioimmunoassay.Results The levels of TNF-?[(2.5 ?0.57)ng/L],IL-2[(9.0?0.83)ng/L] and IL-6 [(97.5?13.1)ng/L] in epilepsy group were significantly higher than those in the NC group[TNF-?(0.89?0.36)ng/L,IL-2(4.3?1.5)ng/L,IL-6(13.3?11.1)ng/L](all P