1.Cystic Adenocarcinoma of prostate: a case report
Ng KL ; Sathiyananthan JR ; Dublin N ; Razack AH ; Lee G
Journal of University of Malaya Medical Centre 2011;14(1):21-22
Prostate cancer is not uncommon amongst the elderly men. Diagnosis is made using histopathology
specimens of Transrectal Ultrasound guided biopsy of the prostate gland. However, prostate cancer
presenting as a intra-prostatic cysts are rare. We report a case of elderly gentleman who presented with
malignant intra-prostatic cysts.
Prostatic Neoplasms
2.Renal angiomyolipomas in the University of Malaya Medical Centre: its spectrum of presentation and management
Koh PS ; Muhilan P ; Dublin N ; Razack AH
Journal of University of Malaya Medical Centre 2009;12(1):39-43
Renal angiomyolipoma, once considered a rare benign renal tumour, is relatively common these days. They account for 0.3-3.0% of all renal masses. Histologically, it is composed of adipose tissue, smooth muscles and blood vessels. Here, we wish to highlight five cases of renal
angiomyolipomas which were presented to the University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia, over a two-year period between June 2005 and June 2007. This study wish to illustrate its varied clinical presentation and the management undertaken for each underlying condition. These cases were presented in the form of spontaneous perirenal haemorrhage, a large asymptomatic renal mass, a small asymptomatic renal mass, a symptomatic renal
angiomyolipoma and a case of renal angiomyolipoma mimicking a renal tumour. Each of these cases varied in its clinical presentation; thus, management has become very challenging to clinicians ranging from conservative management to active intervention, be it operatively or non-operatively.
Angiomyolipoma
3.Chronic myeloid leukaemia presenting as priapism- how should we treat these?
Htun TH ; Dublin N ; Parameswaran M ; Razack AH ; Chua CB
Journal of University of Malaya Medical Centre 2008;11(1):27-29
Priapism is a urological emergency. The treatment for ischaemic priapism is usually
cavernosal aspiration with or without cavernosal irrigation. Some patients may need surgical intervention
-the various shunt procedures. We report a 21-year-old man with priapism secondary to chronic
myeloid leukemia who needed a combined medical and surgical management. He underwent a spongiocavernosal
shunt as well as cytoreductive chemotherapy to achieve complete detumescence. Therefore,
cytoreductive chemotherapy is an adjunct in diffi cult to treat priapism associated with chronic myeloid
leukemia
Leukemia, Myeloid
4.Construction and validation of a Malay version of the overactive bladder screener for assessing urinary tract symptoms in Malaysian population
Muhilan AP ; S Sivaprakasam ; Dublin N ; S Rampal ; Razack AH ; Thun TH ; Chua CB
Journal of University of Malaya Medical Centre 2009;12(2):74-82
The aim of this study was to validate the translation of the Overactive Bladder (OAB) Screener
(OAB V8) to the Malay language. It was to assess the reliability of the screener in the context of a
Malaysian population. The original screener consists of eight symptoms indicative of OAB that has
been proven to be highly sensitive and reliable. Translation was done with a modification of the
Brislin Method using back translation and a panel of experts as a final review panel. The pilot study
had two groups; a symptomatic (n=19 patients) and an asymptomatic group (n=18 patients). All
patients performed the test twice at two week intervals once at the clinic and subsequently at
home. Test-retest method was used for reliability and Cronbach’s alpha for internal consistency.
The translated questionnaire demonstrated good internal consistency in both groups of patients
for all eight items individually and for the total score. Cronbach’s alphas ranged from 0.972 to
0.981 for the symptomatic group and from 0.750 to 0.976 for the asymptomatic group. Testretest
correlation for all items was highly significant. Intraclass correlation (ICC) was high for both
the asymptomatic (ICC ranging from 0.600 to 0.953) and the symptomatic group (ranging from
0.944 to 0.989).The Malay OAB V8 showed itself to be suitable for use, reliable in distinguishing
symptomatic and asymptomatic patients and a valid instrument.