Objective:To compare the effects of different surgical treatment of chronic rhinitis-sinusitis difference,and its impact on transport function of maxillary sinus mucociliary,provide a clinical-surgical sinusitis preferably reference about the treatment of chronic nasal formulation for.Methods:From 2013.9-2014.12,otorhinolaryngology clinic in our hospital,160 cases were diagnosed as chronic nose-as research subjects were randomly divided into four groups of patients with sinusitis were treated from 1 to 4,60 cases in each group;treatment groupl receiving the maxillary sinus ostium augmentation,treatment group 2 received fenestration,treatment group 3 through tears crypt before maxillary sinus surgery,treatment 4 group receiving the maxillary sinus balloon dilatation;after covering the nasal mucosa observed and compared four groups of patients about edema,vesicle formation,bone exposure,scarring,etc.,as well as internal maxillary sinus secretions traits,volume situation,and compared patients after four groups line maxillary sinus cavity and perioral saccharin test biopsy cases three months and six months.Results:The four groups were made after surgery better clinical efficacy,and group efficacy 4 with the other three groups,the effect is most significant (all P ＜0.05),the difference was statistically significant,and after three months and six months,group 4 compared with other surgical group,the Lund-Kernedy score were also lower,MMT time were also lower,the difference was more significant (all P ＜0.05);in the maxillary sinus biopsy aspects:the number of postoperative inflammatory cells and dendritic cells and glandular cell morphology and submucosal edema improved submucosal structures also in the group of four most significant (P＜0.05).Conclusion:Maxillary sinus balloon dilatation treatment chronic nasal sinusitis curative effect is higher,which can effectively improve the cell and submucosal gland cell morphology and sinus mucosa edema,sinus unobstructed drainage effect,and high safety.

Currently,statins are one of the most important medications for the prevention and treatment of cardio-cerebrovascular diseases.In recent years,a large number of clinical studies and metaanalyses have confirmed that statins can effectively reduce the risks of the occurrence and recurrence of ischemic stroke.This article reviews the applications of statins in the primary prevention,acute treatment,and the secondary prevention of ischemic stroke.

Objective To study the expression of vascular endothelial growth factor-C (VEGF-C) and VEGF receptor-3 (VEGFR-3) in non-small cell lung cancer (NSCLC), and to explore its relationship with lymph node metastasis. Methods Sixty patients with NSCLC were studied. The expression of VEGF-C and VEGFR-3 was detected by immunohistochemistry in lung cancer samples, and its relationship to clinical and pathological data was analyzed. Results The positive expression rate of VEGF-C in NSCLC tissues was 68.3% (41/60), the expression rate of VEGFR-3 was 53.3% (32/60). The expression of VEGF-C was related with the degree of cell differentiation in lung cancer. Both the expressions of VEGF-C and VEGFR-3 were positively associated with lymph node metastasis. There was a positive correlation between VEGF-C and VEGFR-3 expressions (r=0.27). Conclusion The expressions of VEGF-C and VEGFR-3 are related to lymph node metastasis in NSCLC. VEGF-C may promote intratumoral lymphangiogenesis via VEGFR-3 and lymphatic metastasis.

Objective To investigate the clinical significance of the urine micro albumin(MA)and urine enzyme detections in early renal injury in children with allergic purpura.Methods 120 patients with allergic purpura were chosen as the research sub-jects and divided into the early renal injury group and non-renal injury group according to whether having the renal injury.Contem-poraneous 40 healthy children were chosen as the healthy control group.The urine MA and urine enzyme levels were detected and compared among the various groups.Results MA was (17.5 ±3.8)mg/L in the study group,transferring(TRF)was (0.56 ± 0.34)mg/L,β2-MG was (0.35 ±0.07 )mg/L,NAG was (18.6 ±5.1 )U/g,which were significantly higher than those in the healthy control group,the differences were statistically significant (P <0.05 );in the early renal injury group,MA was (42.1 ± 21.3)mg/L,TRF was (1.65±0.54)mg/L,β2-MG was (0.43±0.06)mg/L and NAG was (23.1±5.12)U/L,which were signif-icantly higher than those in the non-renal injury group,the differences had statistically significance (P <0.05).Conclusion The de-tection of urine MA and urine enzyme can be used as the indexes for monitoring the early renal injury in children with allergic pur-pura,and is conducive to early discovery,in time intervention and reduce the occurrence of complications.

Objective:To study the clinical results and the hospitalization cost of video-assisted thoracoscopic surgery (VATS) with ligation and suture for the treatment of spontaneous pneumothorax.Methods:Thirteen patients were treated by VATS with ligation and suture.The consumed time of operation,duration of the chest drainage,amount of the chest drainage,percentage of patient discontinuing anodyne within the postoperative 24 hours,the average length of hospitalization and the hospitalization cost were analysed.Results:Satisfactory therapeutic effects were found in all cases without postoperative death and complications. The average hospitalization time was 3 days.VATS with ligation and suture was preferable to transaxillary minithoracotomy (TAMT) in the clinical results.The hospitalization cost is less for VATS with ligation and suture (7372.47?871.3) than that with Endo-GIA (12524.32?2962.18) (P

Objective To explore the feasibility and curative effect of treating tubal pregnancy through the fallopian tube with interventional catheterization decrease the difficulty of the procedure and shorten the consuming time. Methods Applying the method of interventional catheterization of fallopian tube and injecting 0.5mg atropine at the cervix beforehand, then 70mg MTX was administered into the fallopian tube. Results 113 patients were successfully recovered with health except one without any adversary complication. Conclusions The interventional fallopian tube catheterization for treating ectopic pregnancy is a simple, safe, minitraumatic, quick and effective method.

Objective To observe the clinical effects and nursing therapy of Jinchuangkangjungao ointment and infrared therapy in the treatment of chronic skin ulcers .Methods Seventy-five patients with chronic skin ulcers were divided into two groups :the experimental group(n=39) and the control group(n=36) .Jinchuangkangjungao ointment and infrared therapy were applied to the experimental group and the control group underwent conventional treatment ,including debridement ,dressing change and iodine wet compressing .The two group were both given basic nursing therapy .The effect and healing time were observed after 30 days . Results The experimental group′s total effective rate(92 .31% ) was significantly better than that of the control group(69 .44% ) , with significant difference(P<0 .01);The healing time of the experimental group[(11 .98 ± 6 .05)d] was significantly shorten than the control group[(16 .96 ± 7 .13)d] ,with significant difference(P<0 .05) .Conclusion Jinchuangkangjungao ointment combined with infrared therapy had noticeable effect in the treatment of chronic skin ulcers .

10.3969/j.issn.1000-8179.2013.12.001

Objective To explore the relationship of molecular biology characteristic and the treatment outcome,and influence factors of neoadjuvant chemotherapy (NAC) in inflammatory breast cancer (IBC).Methods The clinicopathological data of 103 IBC patients who were treated with NAC from January 2005 to June 2013 were analyzed retrospectively.Immunohistochemical method was used to detect the expression of estrogen receptor (ER),progesteron receptor (PR),human epidermal growth factor receptor 2 (HER-2) and E-cadherin.The treatment outcome were evaluated.Results In 103 IBC patients,ER negative was 48 patients,PR negative was 51 patients,HER-2 positive was 45 patients,E-cadherin positive was 66 patients.The effective rate of chemotherapy was 72.8％ (75/103).The effective rate of chemotherapy in taxane-based group was significantly higher than that in anthracycline-based group [80.6％ (50/62) vs.61.0％(25/41)],and there was significant difference (P ＜ 0.05).The effective rate of chemotherapy in ER,PR,E-cadherin negative patients was significantly higher than that in ER,PR,E-cadherin positive patients [83.3％ (40/48) vs.63.6％ (35/55),82.4％ (42/51) vs.63.5％ (33/52),83.8％ (31/37) vs.66.7％ (44/66)],and there was significant difference (P ＜ 0.05).The effective rate of chemotherapy in taxane-based group with E-cadherin positive patients was significantly higher than that in anthracycline-based group with E-cadherin positive patients [77.5％ (31/40) vs.50.0％ (13/26)] (P ＜0.05).No correlation existed between the expression of HER-2 and the treatment outcome of chemotherapy (P ＞ 0.05).Conclusion ER,PR and E-cadherin negative patients with IBC is chemosensitive to NAC.The positive expression of E-cadherin may be an important factor of chemotherapy resistance.For the patients with E-cadherin positive,taxane-based chemotherapy regimen can achieve a better effective rate.

Objective To assess the current situation and quality of clinical randomized controlled trials(RCTs) designed for accessing the treatment of depressive neurosis with acupuncture and moxibustion. Methods Relative clinical research literatures published from year 1980 to 2008 were collected, and composed into "evaluation to all literature of acupuncture and moxibustion treating depressive neurosis message table", according to the clinical epidemic disease and EBM. The quality evaluation on these trails were performed. Results There were altogether 15 articles included in this study. Among them, 5 articles used the correct randomized controlled trials (33.3%), 10 articles used the diagnostic criteria (66.6%), 10 articles used excluded criteria (66.6%), 12 articles used the therapeutic evaluation criteria (80%), 4 articles used blind treals (26.7%), 5 articles reported quit cases (33.3%), and 9 articles reported the adopted statistical methods (60%)4 articles Conclusion The quality of RCT of acupuncture and moxibustion for depressive neurosis needs to be improved.