Magnetic nanoparticle will become a kind of mean and colloidal solution if it is coated with surfacant.Magnetic nanoparticle has a wide clinical practice because it can produce heat in alternating magnetic fields,especially in malignant tumors thearapy.Magnetic nanoparticle hyperthermia,nano-delivery and magnetic target drug,and intravascular embolization with magnetic particle will bring new hope for tumor patients.

The autonomy is one of the basic authorities of patients.It isn't only an ethical concept,but also can help enhance the efficacy and compliance to a certain extent.The autonomic behavior of the patients isn't as optimistic as we think.The patient's autonomy can be influenced by many factors.We should base on the principles,advantage,respect and communication,to encourage patients to make an appropriate and unbiased decision and change into a collaborative,patient-centered doctor-patient relationship model.

Objective To investigate effects of hydrogen sulfide on hepatic ischemia-reperfusion injury in rats.Methods Thirty healthy male SD rats weighing 220-250 g were randomly divided into sham operation group (S group),ischemia-reperfusion group(IR group) and different doses of hydrogen sulfide groups (H2S1～3 groups),every group contains six rats.In S group hepatic portal was only exposed but not ligated.In IR group the left and middle lobes of hepatic pedicle,portal vein and hepatic artery were clamped for 1 h and then reperfuse.H2 S1～3groups received intraperitoneal injection of NaHS 14,28,56 μmol/kg at 5 min before reperfusion.Blood samples were collected for measuring the activity of alanine transaminase (ALT) and aspartate transaminase (AST) in serum at 6 h after reperfusion.Liver tissue samples were collected for measurement the glutathione (GSH) content and pathologic examination.Results Compared with S group,the activity of ALT and AST in serum was increased,GSH content in liver tissue decreased in IR group ; Compared with IR group,the activity of ALT and AST in serum was decreased,GSH content in liver tissue increased in H2 S1～3 groups.Hepatic tissue pathologic injury was reduced in H2 S1～3 groups as compared with IR group.Conclusion Hydrogen sulfide can reduce hepatic ischemia-reperfusion injury in rats.

Airway remodeling is one of the main pathological changes of bronchial asthma. It has shown that a variety of cytokines, including chemokines, growth factors, matrix proteins, participate in and even strengthen airway remodeling through building complex signal transduction pathways. Many traditional Chinese medicines,such as shegan mahuang decoction,have a regulatory role in airway remodeling.

Objective To study the epidemical status of notifiable infectious diseases in navy from 1992 to 2006,in order to set a scientific basis for working out the measures of preventing from infectious diseases.Methods The reported data were classified by the current national approach and descriptively analyzed concerning infectious diseases during a period of 1992 to 2006 based on the Infectious Disease Surveillance and Reporting System of Chinese PLA.Results 6626 cases of 34 different notifiable infectious diseases were reported in PLA Navy during 1992-2006.Class A,B and C notifiable infectious disease were all reported.There was one death case.Viral hepatitis,dysentery and pulmonary tuberculosis ranked the top situation composing 78.84% of the total cases.The types of infectious diseases during 1992-1999 were less than that during 2000-2006,while the incidence was opposite.Gastrointestinal diseases were the major infectious diseases,accounting for 50.89%.The reported incidence of gastrointestinal diseases declined,and that of respiratory diseases ascended.Blood-borne and sexually transmitted infectious diseases accounted for 18.04%.Natural focal and arthropod-borne disease accounted for 4.95%.Conclusion Certain achievements in prevention and control of infectious diseases have been made since the present century.However,gastrointestinal and respiratory diseases should remain to be regarded,especially for viral hepatitis,pulmonary tuberculosis,dysentery,chicken pox and mumps.In the meantime the propaganda and education on the knowledge of disease prevention should be strengthened among the focus groups.

The platelet membrance glycoprotein plays a key role in the adhesion,aggregation and release of platelet.It is the specific molecular marker for platelet activation.Many studies have confirmed that platelet membrane glycoprotein CD62P may be more sensitive and specific to reflect the occurrence of coronary artery development,CD62P level is positively correlated with the severity.A variety of traditional Chinese medicine can lower the CD62P level,inhibit platelet activation and the treatment play an important role in the treatment.

Objective To investigate the efficacy of Saururaceae lotion in treatment of gynecological inflammation ( chronic cervicitis,vaginitis).Methods 90 patients with gynecological inflammation(chronic cervicitis,vaginitis) were randomly divided into two groups,and each group 45 cases.The observation group was administered with Saururaceae lotion treatment, and the control group was treated with Jieeryin.Clinical efficacy and relapse situation were observed.Results The total effective rate of the observation group was 95.6% , higher than that of the control group(77.8% )(x2 = 5.362.P <0.05) ;The gynecological inflammation recurrence rate the observation group was 4.4% ,lower than that of the control group(33.3% )(x2 = 16.312,P <0.05).Conclusion Saururaceae lotion in treatment of gynecological inflammation was effective,and had low recurrence rate,and it was worthy of clinical application.

Radiation-induced stomatitis is a frequent side effect for head and neck cancer patients undergoing radiotherapy, which affects both the treatment and the life quality. The direct effects of radiation, oxidative stress, transcription factor, proinflammatory cytokine and pathogenic microorganism are involved in the onset of radiation-induced stomatitis. The pathologic process can be divided into five phases including initiation, up-regulation, amplification, ulceration and healing. Understanding of the pathogenesis and risk factors provides basis for prevention and control of radiation-induced stomatitis.

Objective To use puncture and consultation system for improving the needle puncture success rate of pediatric nurses, upgrading the level of puncture technology, reducing patient complaints and increasing patient satisfaction. Methods 200 pediatric patients selected from March,2006 to March, 2010 were divided into the intervention group and the control group, The intervention group adopted puncture and consultation system while the control group did not. The success rate of puncture, patients complaints and patients satisfaction were compared. Results The puncture success rate of pediatric nurses increased,and patients' complaints reduced and patients' satisfaction degree increased in the intervention group compared with that of the control group. Conclusions The pediatric puncture and consultation system in the tertiary hospital not only increases the satisfaction degree of pediatric patients' parents, but also improves the level of puncture technique of pediatric nurses, and has important social effect outside hospital.

Objective To learn current status of elderly depressive disorders in Yuetan community residents to provide evidence for policy making.MethodsCluster sampling method was used to enroll 352 elderly individuals from Yuetan Community for Geriatric Depression Scale(GDS)and self-designed questionnaire.Results The morbidity of elderly depressive disorder was 23.86%(84/352).The awareness rate of risk factor of elderly depressive disorder Was 4.83%to 42.90%.Conclusion The morbidity of elderly depressive disorder of Yuetan Community is higher,and related healthcare education should be strengthened.