1.Effects of dexmedetomidine-propofol-fentanyl combined anesthesia on somatosensory and motor evoked potentials in patients undergoing cervical spine surgery
Sheng LIN ; Shuqin NI ; Dongxiu SUN ; Wei SHAO ; Binghua SHEN
Chinese Journal of Anesthesiology 2010;30(11):1284-1286
Objective To evaluate the effects of dexmedetomidine-propofol-fentanyl combined anesthesia on somatosensory evoked potentials (SEPs) and motor evoked potentials (MEPs) in patients undergoing cervical spine surgery. Methods Thirty-six patients undergoing cervical spine surgery were randomly divided into 2 groups (n = 18 each): propofol-fentanyl combined anesthesia group (group C) and dexmedetomidine-propofol-fentanyl combined anesthesia group (group D). Anesthesia was induced with TCI of propofol and iv injection of fentanyl.After the consciousness disappeared, a laryngeal mask airway was placed and the patients were ventilated. In group D, dexmedetomidine 0.5 μg/kg was injected over 10 min after the consciousness disappeared, followed by an infusion at a rate of 0.5 μg·kg-1 ·h-1 until the end of surgery. In group C, the equal volume of normal saline was administered instead of dexmedetomidine. SEPs (P15-N20) amplitudes and latency were measured and recorded before dexmedetomidine administration and at 10 min of dexmedetomidine infusion. The no-elicitation of MEPs was recorded. Results Compared with group C, there was no significant difference in P15-N20 amplitudes and latency in group D. The no-elicitation rate of MEPs in two groups was 0. Conclusion Dexmedetomidine-propofol-fentanyl combined anesthesia does not affect SEPs and MEPs in patients undergoing cervical spine surgery.
2.Application of clinical nursing pathway in patients applied 64 slice spiral CT examination
Dongxiu FANG ; Hongcui LIU ; Renrong SUN
Journal of Clinical Medicine in Practice 2014;(12):170-172
Objective To investigate the application effect of clinical nursing pathway in patients applied 64 slice spiral CT examination.Methods 80 patients underwent 64 slice spiral CT examination were randomly divided into the observation group and the control group,the con-trol group was received routine nursing while the observation group was used clinical nursing path-way,examination and nursing satisfaction were compared between the two groups.Results Anxiety and depression of examination in the observation group was significantly lower than that in the control group,with statistical significance (P <0.05).Observation and nursing time,the number of examined interrupts patients in the observation group was less than that in the control group,nursing satisfaction was higher than that in the control group,the results revealed that the difference was statistical significant (P <0.05).The difference was not statistical significant in adverse reactions of the two groups (P >0.05).Conclusion Clinical nursing pathway can reduce adverse psychology in patients applied 64 slice spiral CT examination,improve the success rate of inspection and shorten nursing time.So it is high efficient nursing mode.
3.Application of clinical nursing pathway in patients applied 64 slice spiral CT examination
Dongxiu FANG ; Hongcui LIU ; Renrong SUN
Journal of Clinical Medicine in Practice 2014;(12):170-172
Objective To investigate the application effect of clinical nursing pathway in patients applied 64 slice spiral CT examination.Methods 80 patients underwent 64 slice spiral CT examination were randomly divided into the observation group and the control group,the con-trol group was received routine nursing while the observation group was used clinical nursing path-way,examination and nursing satisfaction were compared between the two groups.Results Anxiety and depression of examination in the observation group was significantly lower than that in the control group,with statistical significance (P <0.05).Observation and nursing time,the number of examined interrupts patients in the observation group was less than that in the control group,nursing satisfaction was higher than that in the control group,the results revealed that the difference was statistical significant (P <0.05).The difference was not statistical significant in adverse reactions of the two groups (P >0.05).Conclusion Clinical nursing pathway can reduce adverse psychology in patients applied 64 slice spiral CT examination,improve the success rate of inspection and shorten nursing time.So it is high efficient nursing mode.
4.Comparison between rapid intravenous drip of Shenfu and pumping of Dopamine in interventional therapy of acute inferior wall myocardial infarction
Dongmei ZHANG ; Lihua WANG ; Dongxiu SUN ; Changlei SUN ; Lili DU ; Kejing YAO ; Yao LIU ; Xingcai YU
Chinese Journal of Modern Nursing 2017;23(18):2383-2387
Objective To compare the effect of pressurized rapid intravenous drip of Shenfu and micro-pumping of dopamine on hypoperfusion in percutaneous coronary intervention (PCI) of acute inferior wall myocardial infarction.Methods A total of 80 patients with acute inferior wall myocardial infarction treated with emergency PCI in Chest Pain Unit of Yantaishan Hospital of Yantai City from May 2014 to May 2015 were enrolled. Then these patients were divided into observation group (n=40,pressurized rapid intravenous drip of normal saline and Shenfu) and control group (n=40,pressurized intravenous drip of normal saline with the same pressure combined with micro-pumping of Dopamine) according to random number table. Blood pressure and heart rate per five minutes were observed and recorded before intravenous drug,five to forty minutes after intravenous drug. Besides,the incidence rates of malignant arrhythmia,vomitting,TIMI grade three flows after intrqvenous drug and major adverse cardiovascular events after 30 days of a follow-up were also observed and recorded.Results Systolic pressure,diastolic pressure and mean arterial pressure of patients between two groups all met and maintained to the expectation after treatment with significant differences between two groups (P<0.05). The incidence rates of malignant arrhythmia,nausea and vomitting in observation group were lower than those in control group with significant differences (P<0.05). There was no statistically significant difference in the proportion of TIMI grade three flows and the incidence of major adverse cardiovascular events after 30 days of a follow-up (P>0.05).Conclusions When the hypoperfusion appears during PCI of acute inferior wall myocardial infarction,the pressurized rapid intravenous drip of Shenfu can improve hypoperfusion which is better than Dopamine in the effects of correcting hypotension and reducing the occurrence of adverse events.