1.Survey on mental health and social support of students majored in stomatology in internship
Chengfang TANG ; Yong ZHU ; Dongning ZHANG ; Feng WANG ; Lei WANG
Chinese Journal of Medical Education Research 2013;(5):502-506
Objective To study the mental health conditions of students majored in stomatology and dental technology in internships,and to provide evidences and guidelines for education before and during exercitation.Methods Totally 90 students majored in stomatology and 60 students majored in dental technology in internships were surveyed by the questionnaires of symptom checklist (SCL90)and perceived social support scale (PSSS).Results were analyzed by SPSS 14.0.Measurement data was analyzed using t test comparison between groups,showed as mean ± standard deviation ((x) ± s).Positive screening rate and rate between male and female were analyzed by Mann-Whitney U inspection.The inspection level is α =0.05.Results Scores of somatization,paranoia and anxiety factors among students majored in stomatology were (1.49 ± 0.56),(1.52 ± 0.43),(1.73 ± 0.58),all significantly higher than those of the national norm of youth.Positive rate of mental diseases among students majored in dental technology was 77.59% and their scores of somatization,constraint,anxiety,psychotic factors were (1.69 ±0.55),(2.07 ±0.5),(1.68 ±0.51) and (1.54 ±0.39),all significantly higher than those of students majored in stomatology.There was no difference in the scores of rest factors between the two groups.Scores of PSSS among students majored in dental technology were significantly lower than those of students majored stomatology.Conclusions Students of different majors all suffer from psychological problems with different degrees.Therefore,education,management and social support before and during exercitation should be emphasized in the prevention of psychological diseases.
2.Mutational analysis of NPHS1 gene in children with sporadic steroid-resistant nephrotic syndrome in Southern Chinese Han ethnic group
Daojing WANG ; Zihua YU ; Dachuan MENG ; Rong FU ; Jingjing WANG ; Dongning FENG ; Yonghui YANG
Chinese Journal of Nephrology 2012;28(2):95-100
Objective To elucidate the mutations of NPHS1 gene in children with sporadic steroid-resistant nephrotic syndrome (SRNS) in Southern Chinese Han ethnic group.Methods Peripheral blood samples were collected for genetic analysis from 40 patients with sporadic SRNS and 50 healthy volunteers as control.Genomic DNA was isolated from peripheral blood leucocytes.Twenty-nine exons and exon-intron boundaries of the NPHS1 gene were amplified by polymerase chain reaction.Mutational analysis was performed by DNA sequencing directly.Results Seven variants,928G>A(D310N),2677A>G (T893A),2869G>C (V957L),IVS8+30C>T,IVS21+14G>A,IVS25-23C>T and *142T>C,of NPHS1 gene were found in 6 of 40 children with sporadic SRNS,whereas they were not found in 50 healthy controls.2677A >G,IVS8 +30C >T,IVS21 +14G>A,IVS25-23C >T and *142T>C were novel.Moreover,thirteen already reported NPHS1 polymorphisms,294C>T,349G>A,IVS3+15C>T,IVS3+61A>G,803G>A,IVS8+68A>G,1339G >A,1802G >C,2223C >T,2289C >T,IVS24 +36C >T,3315G>A and IVS27 +45C >T,were detected in some patients and controls. Conclusions NPHS1 mutations in 6 of 40 children with sporadic SRNS in Southern Chinese Han ethnic group (15%) are detected.NPHS1 mutations are existed in Southern Chinese children,so it is necessary to perform the mutation analysis of NPHS1 gene in those children patients.
3.Influence factors of electrode regulatory regions in deep brain stimulation
Chinese Journal of Neuromedicine 2016;15(12):1290-1293
Deep brain stimulation (DBS) is an effective way to treat many movement disorders.The volume of tissue activated (VTA) by DBS refers to the region regulated by pulses,which is generated by the electrode contacts.It is associated with the therapeutic effect and side effects;as a result,precise regulation of VTA plays an important role in patient-specific treatment.This article summarizes the factors which affect VTA.
4.Therapeutic Efficacy and Safety of Compound Muni Ziqi Granules in the Adjuvant Treatment of Chloasma: A Systematic Review
Tong YU ; Yun FENG ; Huanhuan WU ; Shuiying HE ; Dongning ZHANG ; Jing YANG ; Hailong YIN ; Qiang YIN
China Pharmacy 2018;29(3):405-409
OBJECTIVE: To systematically evaluate therapeutic efficacy and safety of Compound muni ziqi granules in the adjuvant treatment of chloasma, and to provide evidence-based reference for clinical treatment. METHODS; Retrieved from Chinese Journal Full-text Database (CJFD), China Scientific Journal Database (CSJD), Wanfang database, Medline and Embase, randomized controlled trials (RCTs) about therapeutic efficacy (total response rate, cure rate, the decrease level of E2, FSH and LH in serum) and safety of Compound muni ziqi granules alone or combined with routine drug (trial group) vs. routine drug (control group) in the treatment of chloasma were collected. Meta-analysis was conducted by using Rev Man 5. 3 statistical software after data extraction of clinical studies meeting inclusion criteria and quality evaluation with Cochrane systematic evaluator manual 5. 1. 0. RESULTS: Totally 12 RCTs were enrolled, involving 1 100 patients. Results of Meta-analysis showed that total response rate [OR=2. 84, 95%CI(2. 20, 3. 67), P<0. 001], cure rate [OR=2. 11, 95%CI(1. 59, 2. 79),P<0. 001],decrease level of Ez [OR=-98. 64, 95% CI (-110. 84, -86. 44), P <0. 001], decrease level of FSH [OR=-1. 85, 95%CI(-2. 58,-1. 11),P<0. 001] and decrease level of LH [OR= - 5. 85, 95% CI (-6. 83, -4. 87), P<0. 001] in trial group were significantly better than control group, with statistical significance. In trial group, a few patients suffered from the increase of menstruation, the decrease of menstruation, temporary pigmentation and transient burnout; but all symptoms did not affect the treatment. CONCLUSIONS: Compound muni ziqi granules show definite clinical efficacy and good response rate in the adjuvant treatment of chloasma with mild ADR.
5.Quality control of robotic natural orifice specimen extraction surgery for right colon cancer
Dongning LIU ; Wenjun HU ; Weijie LU ; Feng XIAO ; Ruixiang ZOU ; Taiyuan LI
Chinese Journal of Gastrointestinal Surgery 2024;27(8):794-798
Robotic natural orifice specimen extraction surgery for right colon cancer has been conducted with progressive refinements. To facilitate the standardized implementation of this surgical technique, the adoption of rigorous quality control measures is paramount. The present article outlines the key aspects of quality control for robotic natural orifice specimen extraction right hemicolectomy surgery, encompassing the preoperative, intraoperative, and postoperative phases, as well as the training and credentialing requirements for the operating surgeons, with the aim of providing a reference framework to facilitate the safe and reliable implementation and dissemination of this minimally invasive approach for right colon cancer.
6.Quality control of robotic natural orifice specimen extraction surgery for right colon cancer
Dongning LIU ; Wenjun HU ; Weijie LU ; Feng XIAO ; Ruixiang ZOU ; Taiyuan LI
Chinese Journal of Gastrointestinal Surgery 2024;27(8):794-798
Robotic natural orifice specimen extraction surgery for right colon cancer has been conducted with progressive refinements. To facilitate the standardized implementation of this surgical technique, the adoption of rigorous quality control measures is paramount. The present article outlines the key aspects of quality control for robotic natural orifice specimen extraction right hemicolectomy surgery, encompassing the preoperative, intraoperative, and postoperative phases, as well as the training and credentialing requirements for the operating surgeons, with the aim of providing a reference framework to facilitate the safe and reliable implementation and dissemination of this minimally invasive approach for right colon cancer.