1.Analysis of chest X-ray in 87 cases of neonatal respiratory distress syndrome
Chinese Journal of Primary Medicine and Pharmacy 2012;19(2):193-194
Objective To explore the diagnostic value of chest X-ray in neonatal respiratory distress syndrome.Methods 87 children with NRDS were selected.Then bedside radiography was conducted with the Philip Pracelx100 mobile X-ray machine,and the children with confirmed NRDS were recorded,and the children screening by chest X-ray review were analyzed.Referenced the NRDS image diagnostic criteria,the disease grading was carried out according to the lung field light transmission reduction and air bronchogram extent.Results 20 cases in the first grade,35 cases in the second grade,28 cases in the third grade,4 cases in the fourth grade.Limitations of miliary shadows in 15 cases ;60 cases of impaired lung field transmittance,51 patients presented with ground-glass change and air bronchogram ;4 cases in “ white lung”.Conclusion Chest X-ray for NRDS had important value of diagnostic,differential diagnostic and prognosis.
2.Immunomodulatory effect of calf spleen extractive injection on immunocompromised mice
Chinese Journal of Biochemical Pharmaceutics 2014;(2):58-60
Objective To investigate the effect of Calf Spleen Extractive Injection(CSEI) on immune function of immunocompromised mice. Methods BALB/C mice were divided into normal group (n=20), model group (n=20) and positive control group (n=20), CSEI high dose group (1.20 mL/kg, n=20), middle dose group (0.60 mL/kg, n=20) and low-dose group (0.30 mL/kg, n=20). Besides the normal group, mice in other groups were intraperitoneal injected cyclophosphamide at dose of 80 mg/kg for three consecutive days to induce immunocompromised model. Continuous dosing after 10 days to viscera index, index, natural killer cells (natural killer cell, NK) kill rate, the number of peripheral blood leukocytes (white blood cell, the WBC), lymphocyte count (lymphocytes, LYM) and serum against sheep red blood cells (the Sheep Red blood cell, SRBC) IgG levels as examining index, verify the CSEI effect on the regulation of immune function was low immune function in mice. Results Compared with model group, CSEI groups of high middle and low dose had improved viscera index, phagocytic coefficient, NK cell killing activity, serum specific antibody level, peripheral WBC count and lymphocyte count(P<0.05). Conclusion CSEI has possess immunomodulatory effects on the immunocompromised mice.
3.Research into featured content P.E class to Chongqing medical colleges foreign students
Chinese Journal of Medical Education Research 2011;10(5):560-562
This article applies documentary,expert interview, questionnaire and other methods to study the physical education teaching of foreign students in Chongqing, and explores the construction of P.E features teaching content teaching to foreign students in medical colleges.
4.A research about the methods of hemostasis by compression after femoral artery puncture for hemodialysis patients
Chinese Journal of Practical Nursing 2006;0(16):-
Objective To study the proper method of hamotasis by compression after femoral artery puncture for hemodialysis patients, and then decline the incidence rate of complication. Methods There were 107 hemodialysis patients in the observation group and 106 patients were in the control group. The method of using hard board paper press the point of puncture was adopted in the observation group, the traditional method was used in the control group. Compare the incidence rate of complication and the braking time after the puncture in the two groups. Results The incidence rate of complication in the control group was significant higher than that of in the observation group, P
5.Research and analysis of college students' depression status quo and physical exercise inter-vention measures
Chinese Journal of Medical Education Research 2014;(8):833-835,836
According to the epidemic situation of depression of college students, pathogenesis and intervention measures were analyzed by literature method in this paper, focusing on exploring the principles of exercise intervention in college sports-related depression, the benefits of exercise intensity and precautions. The purpose was to provide a way for college students' reasonable intervention, as well as provide a reference for further prevention treatment of depression of college students.
6.Expression of cholecystokinin receptor B in a variety of human tumor tissues and cells
Chongqing Medicine 2014;(13):1584-1586,1590
Objective To investigate the expression of cholecystokinin receptor B(CCK-BR)in a variety of human tumor tissues and cells.Methods RT-PCR and Western Blot were used to detect the expression of CCK-BR mRNA and protein in human gastric cancer AGS and SGC-7901cells,human hepatoma cancer HepG-2 cells,human neuroblastoma SH-SY5Y cells and human lung canc-er A549 and NCI-H446 cells,human prostate cancer DU145 cells,human bladder cancer T24 cells.CCK-BR expression was detected in the clinical cancer tissues including the stomach,breast,cervical,bladder,lung and liver and AGS and SGC-7901 cells by immuno-histochemical and immunocytochemical methods.Results CCK-BR mRNA and protein were express in the cytoplasm and cell mem-brane of the above 8 cell lines.Positive expression of CCK-BR was discovered in the above cancer tissues.Conclusion CCK-BR are expressed in a variety of human tumor tissues and cells.
7.On the Development of Small and Medium - sized Enterprises in Pharmaceutical Industry
China Pharmacy 2001;12(4):199-201
OBJECTIVE: To discuss about the strategy of small and medium-sized pharmaceutical enterprises' development.METHODS: According to the analysis of different kinds of small and medium-sized pharmaceutical enterprises and the discussion of competition strategy, this paper brings forward the successful development model of small and medium-sized pharmaceutical enterprises.RESULTS & CONCLUSION: Small and medium-sized pharmaceutical enterprise advanced in technology is a successful development model in future. In order to get the development of this kind of enterprise, we should adjust our tactis in aspects of enterprise and goverment.
8.Effect of heparin slow-release stent on angiogenesis and cardiac function of patients with acute myocardial infarction
Chinese Journal of Tissue Engineering Research 2015;19(30):4815-4819
BACKGROUND:Bare-metal stent for treatment of myocardial infarction may improve cardiac function to some extent, but it is prone to induce thrombus. OBJECTIVE:To explore the effect of heparin slow-release stent on angiogenesis and cardiac function of patients with acute myocardial infarction. METHODS:A total of 87 patients with acute myocardial infarction were enroled, including 47 males and 40 females, aged 55-81 years. These patients were divided into observation group (n=45) with percutaneous coronary intervention with heparin slow-release stent and control group (n=42) with percutaneous coronary intervention with bare metal stent. The folow-up period was 12 months, and angiogenesis, cardiac function improvement and adverse cardiac events in the two groups were observed and compared. RESULTS AND CONCLUSION:The new blood vessel density, myocardial survival area and left ventricular ejection fraction were al higher in the observation group than the control group (P < 0.05). At 3 months after intervention, there was one case of revascularization and one case of recurrent acute myocardial infarction in the observation group; in the control group, there was case of revascularization, one case of recurrent acute myocardial infarction and one case of sudden cardiac death, and there was no difference between the two groups. These findings indicate that that percutaneous coronary intervention with heparin slow-release stent has good biocompatibility and can effectively promote the regeneration of blood vessels and improve cardiac function of patients with acute myocardial infarction.
9.Endothelium-derived hyperpolarizing factor
Dongmei CHEN ; Hai WANG ;
Chinese Pharmacological Bulletin 1987;0(03):-
There is another factor involving in endothelium dependent relaxation besides NO, which is independent of cGMP, EDHF. Its hyperpolarization mechanism may be related to the open of calcium dependent K + channels(K + Ca). NO, PGI 2,H 2O 2 and cytochrome P450 derived metabolite of arachidonic acid are all the candidates of EDHF. In the normal blood vessels, the influence of EDHF on endothelium dependent relaxation is little. But in some diseases, when the production and effect of NO is disturbed ,the mechanism of EDHF may play a specially important role.
10.Quality Standard of Zhijishu Lotion
China Pharmacy 2001;0(09):-
OBJECTIVE:To establish the quality standard of Zhijishu lotion. METHODS: Phellodendron chinense, Radix et Rhizoma Rhei,Radix Sanguisorbae in Zhijishu lotion was qualitatively identified by TLC, and the content of berberine hydrochloride was determined by HPLC. RESULTS: The TLC spots of the constituents were clear, well-separated and specific. The linear range of berberine hydrochloride was 0.237 5~1.900 0 ?g(r=0.999 9) and the average recovery was 99.30%(RSD=0.03%,n=6).CONCLUSION: The established quality standard is applicable for the quality control of Zhijishu lotion.