1.Analysis of 20 cases with breast disease examined by Color Doppler Flowing Imaging
Chinese Journal of Primary Medicine and Pharmacy 2014;(14):2155-2156
Objective To analyze the clinical diagnosis value of Color Doppler Flowing Imaging in the diag-nosis of female breast mass ,discuss sonographic features of breast hyperplasia and maeexy dyeplesle .Methods The data of 20 patients with breast disease which diagnosed by Color Doppler Flowing Imaging were retrospectively ana -lyzed,some cases were conducted postoperative pathological examination .Results In all cases,13 cases were breast fibroadenoma(65.0%),6 cases were maeexy dyeplesle (30.0%),1 case was metaplastic squamous cell carcinoma (5.0%).The typical fibroadenoma had regular shape ,clear boundary and homogeneous internal echo ,and were mar-ginated smoothly with a fine echoic capsule and a lateral wall shadowing .Conclusion Color Doppler ultrasonography is an approach for noninvasive and simple examination of breast lesion ,and worthwhile for spreading in clinical prac-tice .Analysis of the ultrasonographic performance of breast fibroadenoma is helpful to the diagnosis and differential di -agnosis of breast disease ,which can also improve the level of diagnosis .
2.The attitudes of medical students regarding to organ donation compensation
Chinese Journal of Organ Transplantation 2015;36(3):176-179
Objective To investigate the attitudes of medical students regarding to organ donation compensation.Method A self administered questionnaire was distributed to 600 medical students selected randomly from two medical universities in China between January 2013 and January 2014.The questionnaire included demographics and core questions related to medical student's attitudes regarding organ donation compensation.Result A total of 600 questionnaires were distributed and 592 valid responses were received,including 150 doctoral students,143 master students and 299 undergraduate students.In all,69.8% of medical students believed that compensation for organ donor was essential.Nearly 60.5 % believed financial compensation would increase the rate of organ donation but would not tarnish the behavior of organ donors (64.7%).At the same time,over 70% of medical students believed that financial compensation would increase the number of living organ donation.With regarding to the ways of compensation,most of the students (80.4%) were in favor of priority on waiting list.Reducing or free of hospitalization costs (50.4%) and increasing the reimbursement ratio of medical insurance (41.8%) were also the acceptable compensation ways to medical students.Conclusion Most of medical students believe that it is essential to give compensation to organ donors.Enjoying the priority on waiting list,reducing or free of hospitalization costs and increasing the reimbursement ratio of medical insurance are the reasonable incentive methods.
3.Effect of Changle (Rare Earth Complex) on Kidney Antioxidation in Rats
Journal of Environment and Health 1989;0(06):-
Objective To explore the effect of low dose Changle (rare earth complex) on the antioxidation in rats kidney. Methods The activities of Cu-Zn SOD,CAT,LPO and GSH-Px in the rat kidney were determined by biochemical methods after the rats (Wistar rats) were given different doses of Changle by gavage for 6 months respectively. Results The activity of Cu-Zn SOD and CAT in the 10.0 and 20.0 mg/kg groups reduced significantly,but the activity of LPO and GSH-Px increased. The activity of Cu-Zn SOD and CAT in the 2.0,0.2 and 0.1 mg/kg groups increased,but LPO reduced. Conclusion High exposure to Changle may enhance the peroxidation,but low exposure to Changle may enhance the antioxidation in rat kidney.
4.Effect of Bushen Yiqi Hexue Recipe on the Endometrial Gland Apoptosis in Blastocyst Implantation Dysfunctional Mice
Dongmei HUANG ; Guangying HUANG ; Fuer LU
Journal of Traditional Chinese Medicine 1993;0(07):-
Objective To observe the effect of Bushen Yiqi Hexue Recipe(Recipe to reinforce kidney,replenish qi and harmonize blood)on the endometrial gland apoptosis in blastocyst implantation dysfunctional mice.Methods The mice models of blastocyst implantation dysfunction were made and divided into control,model and treated groups with 30 in each.Pregnancy rate,number of implantation blastocysts,the expression of proliferating cell nuclear antigen(PCNA),bax,bcl-2 and activated Caspase-3 were observed.Results Compared with the control group,pregnancy rate and mean implanted blastocysts in the model group were remarkably reduced.Compared with the model group,pregnancy rate and mean implanted blastocysts in the treated group were significantly improved(P
5.Analysis of 451 cases with breast disease examined by Color Doppler Flowing Imaging
Dongmei HUANG ; Tao WANG ; Zunhui LU
Chinese Journal of Primary Medicine and Pharmacy 2012;19(20):3070-3071
ObjectiveTo investigate the value of Color Doppler Flowing Imaging in the diagnosis of female breast diseases,analysis of the clinical characteristics of breast disease.Methods The data of 451 patients with breast disease which diagnosed by Color Doppler Flowing Imaging were retrospectively analyzed,the statistical results and clinical treatment were analyzed finally.Results In all cases,the top three were breast hyperplasia,breast fibroids,and breast cancer,accounting for 56.1%,10.6% and 5.3% ;breast hyperplasia was the highest incidence in all ages,and it showed an increasing trend before the age of 50,gradually decreased after 50 years old; the breast adenofibroma was the highest incidence in the 30 years of age and gradually decreased with increasing age;breast cancer frequently occurring in women after the age of 60,but the deterioration tendency often appears in the age 40 to 50.ConclusionTo diagnose the breast disease by Color Doppler Flowing Imaging,the doctor should combine with breast disease characteristics of the disease,as well as patient age,medical history and other factors on the results of a comprehensive diagnosis.
6.The use of urine LH test paper associating basal body temperature in treatment of infertility
Dongmei DONG ; Chunyan MENG ; Nuojie HUANG
Chinese Journal of Primary Medicine and Pharmacy 2008;15(2):254-255
Objective To explore the use of urine LH test paper associating basal body temperature in ovulation monitoring and conception guiding in anovulatory infertility.Methods We used clomiphene to treat 100 anovulatory infertility patients.Then we recorded basal body temperature and used urine LH test paper in morning to determine whethere there is urine LH peak between the 12th to 20th day of menstrual cycle.If the patient become pregnant,we stop observation.If not,we observed them until the third treatment cycle completed.Result Before treatment,both the urine LH test paper and basal body temperature showed there was no ovulation.After treatmend,we observed 199 menstrual cycle.There were urine LH peak in 149 menstrual cycle.And there were double phase body temperature in 158 treat cycle.The lowest body temperature appeared in the urine LH peak day or after it.71.1%of the lowest body temperature emerged in one or two days after the urine LH peak appeared.76 patients in our study become pregnant,pregnancy rate is 76%.Conclusion Urine LH test paper associating basal body temperature is convenient and easy tO learn.It is a good way in ovulation monitoring and conception guiding.
7.Experimental study of lanthanum nitrate on rat pancreas in type 2 diabetes INSR,IRS1 and apoptosis of cells
Dongmei LI ; Kexin HUANG ; Hongxi MA
Chinese Journal of Immunology 2014;(7):888-892
Objective:To explore the effects of lanthanum nitrate low-dose on 2 type diabetic rat pancreas INSR ,IRS1 and apoptosis of cells.Methods:The 50 male Wistar rats were randomly divided into normal control group (10) and model group(40),and were given normal diet and high-fat high-sugar diet.After 8 weeks,making the module intraperitoneal injection of streptozotocin (STZ,30 mg/kg) rats to induce type 2 diabetes model ,after a successful modeling experimental animals were divided into three groups namely the control group,diabetic model group and La(NO3)3 treatment group,three groups of rats were given daily saline,saline,lanthanum (0.2 mg/kg) nitrate administered a month ,then were sacrificed blood and pancreas.By radioimmunoassay to detect glucose ,insulin levels(in rat serum);by ELISA to detect the protein content of INSR and IRS 1(in rat serum);by immunohistochemistry to detect the protein expression levels of INSR and IRS1(in rat pancreas tissue);TUNEL apoptosis detection kit was used to detect pancreatic tissue percentage of apoptosis;HE staining was used to detect pathological changes of the pancreas.Results: Compared with the normal control group,diabetic model rats blood glucose and pancreatic tissue apoptosis rate were significantly increased ,blood insulin,INSR and IRS1 protein content and pancreatic tissue the protein expression levels of INSR and IRS 1 were significantly reduced ,difference was statistically significant ( P<0.01 );La( NO3 ) 3 treatment group blood glucose and pancreatic tissue apoptosis rate were slightly elevated ,blood insulin , INSR and IRS1 protein content and pancreatic tissue the protein expression levels of INSR and IRS 1 were slightly reduced significantly(P<0.05);Light microscopy showed pancreatic tissue in the control group closely arranged ,plump,large volume islet pancreatic tissue of diabetic rats in groups evacuate more smaller islet volume ,pancreatic tissue lanthanum nitrate basic set tight,plump,slightly islet volume small.Conclusion:Oral lanthanum nitrate can be lowered blood sugar levels and inhibiting apoptosis of pancreatic tissue ,increased insulin levels and the protein expression levels of INSR and IRS 1 in pancreatic tissue ,have a protective effect on diabetic rat pancreas .
8.Social Psychological Analysis and Implications of Internet Public Opinion on Hospital Violence
Xiaoqiang QIN ; Wenqiang YIN ; Dongmei HUANG
Chinese Medical Ethics 2015;(1):21-25
Objective:To investigate the public attitudes towards violence incidents from the perspective of in-ternet users, by the means of collecting the hospital violence incidents on the internet. Methods:Selected 7 cases of typical hospital violence and divided those comments into three categories, namely,support the medical side,support the patient side and other. The proportions of all kinds of attitudes were analyzed. Summarize the in-centives of hospital violence and analyze the attitudes of internet users from the perspective of social psychology. Results:Internet users had different attitudes to these 7 cases of hospital violence incidents. The proportion of support the medical side was from 0 . 66% to 95 . 82%, and the proportion ofsupport the patient side was from 0. 18% to 81. 25%. This was mainly due to the in-group favoritism, stereotypes, moral judgment and emotional tendencies of internet public opinion and media-induced and other factors. In internet users' view, the low profes-sional ethical quality is considered the most important incentives, and the proportion was 43. 05%. Conclusions:The tendency of the media coverage has an important influence on the attitude of internet users. Policy makers should correctly treat with the two sides of network public opinions, the hospitals should improve the ability to re-spond to public opinion, the media should regulate coverage and publicity.
9.Application of radio frequency identification technology in the logistics management of modern medical supplies
Dongmei ZOU ; Yinger CAI ; Yaner HUANG
China Medical Equipment 2015;(9):77-78,79
Objective:To understand the status of medical supplies management and explore the application of RFID technology in medical supplies management.Methods: The implementation of inventory management summarizes some of the experiences from medical supplies, medical supplies in the future direction and management to provide some basis for the implementation of standardized medical supplies, systematic and comprehensive management.Results: Reduce health care costs and improve the level of medical supplies management and accelerate the flow of funds has important significance for the sustainable development of the hospital.Conclusion:The role played by medical supplies and health care practice in the status is irreplaceable, RFID technology as an advanced automatic identification and data capture technologies in the medical field in the future become a hospital for medical goods logistics management indispensable component.
10.Clinical analysis of different intraperitoneal hyperthermic chemotherapy drugs in the treatment of advanced ovarian cancer
Yueming ZHAO ; Dongmei HUANG ; Xinxin SUN
The Journal of Practical Medicine 2017;33(8):1320-1323
Objective To explore short term curative effects and adverse reactions of two different kinds of intraperitoneal hyperthermic chemotherapy (IPHC) drugs in the treatment of advanced ovarian cancer after cytoreductive surgery.Methods 76 patients with advanced ovarian cancer in the Second Affiliated Hospital of Zhengzhou University from July 2013 to November 2015 were divided into two groups:single-drugs group of 36 patients (IPHC with 5-fluorouracil after cytoreductive surgery combined with intravenous chemotherapy),combined treatment group of 40 patients(IPHC with 5-fluorouracil and carboplatin after cytoreductive surgery combined with intravenous chemotherapy).Short term curative effects,postoperative clinical indicators and adverse reactions of chemotherapy in two groups were compared and analyzed.Results The CA125 effective rates in single-drugs and combined treatment group were 86.11% and 95%,and the difference showed statistically significant differences (P > 0.05).The ascites remission rates in single-drugs and combined treatment group were 97.22% and 97.5%,and the difference between two groups showed no statistically significant differences (P > 0.05).Adverse drug reactions showed statistical difference in distribution of the bone marrow,liver damage and gastrointestinal toxicity.No statistical difference were found between the two groups in terms of distribution of renal damage and cardiovascular system damage.Conclusion IPHC after cytoreductive surgery in the treatment of advanced ovarian cancer is an effective means as adjuvant chemotherapy.The short-term curative effect of combined treatment group is obvious and adverse reactions can be tolerated.IPHC can be applied according to the patient's specific clinical situation.