1.Parsing to“the Theory of Spleen and Stomach”Treat“Diet Injury”
Journal of Zhejiang Chinese Medical University 2015;(9):692-694
Objective]Analysis of related theory that“the theory of spleen and stomach”treats“diet injury”, to explore principle-method-recipe-medicines’guiding significance for treatment of internal injuries caused by“diet injury”to explore the related theory’s guiding significance for treatment of internal injuries caused by“diet injury”(This is the related theory to“the theory of spleen and stomach”treating“diet injury”).[Method]Through the process of diagnosis and treatment of three cases analysis(They are“drinking wound”case, dizziness case and insomnia case), expound the argumentation thinking to“the theory of spleen and stomach”treating“diet injury”, principle of prescription medication, and matters needing attention, etc. Through the analysis of diagnosis and treatment process, expound the argumentation thinking to“the theory of spleen and stomach”treating“diet injury”, principle of prescription medication, and matters needing attention. Including the prescription of treatise on febrile disease———Wuling powder’s application in the“diet injury”,Gehuajiejiu soup, Zhishu pill, Hezhong pill’s application in the“drinking wound”.[Result] Understand related theory that the“the theory of spleen and stomach”treats “diet injury”, specific therapeutic principle for sweating, the urine and digestion. Including the prescription of treatise on febrile disease—Wuling powder’s application in the“diet injury”,Gehuajiejiu soup, Zhishu pill, Hezhongpill’s application in the“drinking wound”, Wuling powder, Gehuajiejiu soup are dehumidification by sweating and the urine, Zhishu pill, Hezhong pill ,etc are helping digestion.“The theory of spleen and stomach”treating“diet injury”,prescription and symptoms are consistent. Clinical efficacy of three consilias is satisfaction. Among them, drinking wound, shares proprietary Chinese medicine medicinal properties to achieve and anti-nausea, points up and down digestive purpose of alcohol. Gehuajiejiu soup points up and down digestive purpose of alcohol warning patients at the same time; The dizziness, Wuling powder and Banxiazhishu pill wet Xiaoshi with use and effect;Insomnia, emphasis will be placed on the medication method of small amount many times, and“Nursing mind modulation spleen and stomach”, cooperating with use, treatment effect is obvious. [Conclusion]Using the related theory of“the theory of spleen and stomach”is worth clinical exploration to treatment of clinical disease caused by the“diet injury”, because it is dialectical correctly, curative effect is better.
2.Immunomodulatory effect of calf spleen extractive injection on immunocompromised mice
Chinese Journal of Biochemical Pharmaceutics 2014;(2):58-60
Objective To investigate the effect of Calf Spleen Extractive Injection(CSEI) on immune function of immunocompromised mice. Methods BALB/C mice were divided into normal group (n=20), model group (n=20) and positive control group (n=20), CSEI high dose group (1.20 mL/kg, n=20), middle dose group (0.60 mL/kg, n=20) and low-dose group (0.30 mL/kg, n=20). Besides the normal group, mice in other groups were intraperitoneal injected cyclophosphamide at dose of 80 mg/kg for three consecutive days to induce immunocompromised model. Continuous dosing after 10 days to viscera index, index, natural killer cells (natural killer cell, NK) kill rate, the number of peripheral blood leukocytes (white blood cell, the WBC), lymphocyte count (lymphocytes, LYM) and serum against sheep red blood cells (the Sheep Red blood cell, SRBC) IgG levels as examining index, verify the CSEI effect on the regulation of immune function was low immune function in mice. Results Compared with model group, CSEI groups of high middle and low dose had improved viscera index, phagocytic coefficient, NK cell killing activity, serum specific antibody level, peripheral WBC count and lymphocyte count(P<0.05). Conclusion CSEI has possess immunomodulatory effects on the immunocompromised mice.
3.Effect of milrinone on refractory heart failure
Chinese Journal of Primary Medicine and Pharmacy 2014;21(12):1801-1803
Objective To investigate the effects of the milrinone in adjuvant treatment of intractable heart failure.Methods 60 cases of patients with intractable heart failure were randomly divided into observation group and control group according to hospitalization sequence,30 cases each group.The control group was given conventional therapy for heart failure,the observation group based on the use of milrinone.Changes of cardiac function index,NT-proBNP were compared between two groups before and after medication,and recorded the adverse reactions and the efficacy evaluation.Results After taking drugs,HR,LVEDD of the two groups were significantly decreased(t =5.31,5.92,4.61,4.22,all P < 0.05),SV,LVEF and 6 minutes walking distance increased significantly(t =7.22,4.78,8.78,4.56,4.11,4.05,all P < 0.05) ; group HR,LVEDD were significantly lower than those in the control group(t =4.31,4.92,all P <0.05).SV,LVEF and 6-minute walking distance was significantly higher than that in the control group(t =4.31,4.92,4.11,all P < 0.05).After taking drugs,the observation group NT-proBNP levels decreased significantly than before treatment (t =14.55,P < 0.05),and significantly lower than that in the control group (t =7.12,P < 0.05).No significant change in NT-proBNP levels before and after treatment in control group was found (t =1.03,P > 0.05).The observation group in the total effective rate was 93.33 % (28/30),the control group was 63.33% (19/30),the difference was statistically significant(x2 =5.26,P < 0.05).5 cases of adverse reactions to the observation group,4 patients in the control group,no significant difference in the adverse reactions was found between the two groups (x2 =0.67,P > 0.05).Conclusion Low dose,short-term use of milrinone can make the heart function of patients with refractory heart failure was obviously improved,significantly improve the efficacy with higher safety.
4.Expression and significance of Pokemon protein and p53 protein in ovarian carcinoma
Chinese Journal of Primary Medicine and Pharmacy 2014;21(12):1782-1784
Objective To explore the expression of Pokemon protein and p53 protein in ovarian carcinoma and assure the relationship with clinicopathologic parameters.Methods 52 cases of ovarian cancer were enrolled as the observation group,60 cases of benign ovarian tissue as the control group.Expression of Pokemon protein and p53 protein were detected by immunohistochemistry.Results The positive rate of Pokemon protein were respectively 69.2% (36/52) in the observation group and 11.7% (7/60) in the control group,a significant differences between the two groups (x2 =12.74,P <0.01).The positive rate of p53 protein were respectively 78.8% (41/52) in the observation group and 15.0% (9/60) in the control group,a significant differences between the two groups(x2 =22.71,P < 0.01).Pokemon protein expression were associated with ovarian cancer tumor invasion depth (x2 =9.16,P < 0.05),clinical stage(x2 =5.86,P < 0.05),lymph node metastasis (x2 =32.28,P < 0.01) and recurrence (x2 =27.08,P < 0.01) and no significant relationship with tumor differentiation (x2 =0.82,P > 0.05).p53 protein expression were associated with ovarian cancer tumor invasion depth (x2 =8.24,P < 0.05),clinical stage (x2 =9.24,P < 0.05),lymph node metastasis (x2 =19.62,P < 0.01) and recurrence (x2 =21.16,P < 0.01) and no significant relationship with tumor differentiation(x2 =0.77,P >0.05).By correlation analysis,Pokemon protein expression had a significant positive correlation and p53 protein(r =0.297,P < 0.05).Conclusion Pokemon protein and p53 protein had closely related with diagnosis,lesion degree and prognosis in ovarian cancer.
5.Clinical analysis of arterial perfusion intervention combined with radiation and chemotherapy in the treatment of locally advanced cervical cancer
Chinese Journal of Postgraduates of Medicine 2014;37(15):46-48
Objective To analyze the effect of artery perfusion intervention combined with radiation and chemotherapy in the treatment of locally advanced cervical cancer,and to provide clinical reference.Methods One hundred and eighteen cases with locally advanced cervical cancer patients were divided into observation group and control group by random digits table method,each group 59 cases,all patients in two groups received preoperative chemoradiation,observation group based on this,and added arterial perfusion interventional chemotherapy,compared the clinical curative effect of two groups.Results The effective rate in observation group was significantly higher than that in control group[93.22%(55/59) vs.77.97%(46/59)] (x2 =5.567,P=0.018).Seventeen cases in observation group with Ⅰ and Ⅱ degree of nausea,vomiting,2 cases with Ⅲ degree of nausea,vomiting,4 cases with Ⅰ degree of bone marrow suppression,the incidence of adverse reactions were 38.98%(23/59);18 cases in control group with Ⅰ and Ⅱ degree of nausea,vomiting,3 cases with bone marrow suppression,the incidence of adverse reactions were 35.59% (21/59),there was no statistically significant difference between two groups (x2 =0.145,P =0.703).Conclusions Preoperative arterial perfusion intervention combined with chemoradiotherapy can effectively improve the curative effect for locally advanced cervical cancer,and has no increase in adverse reactions,and has important clinical value.
6.Pay more attention to the selection of proper surgical timing and method for oculoplasty in the pediatric
Ophthalmology in China 2006;0(06):-
The pediatric population with the orbital and eyeball malformations has been an important part in ophthalmic plastic surgery.The pediatric is with great difference from adult in physiology and anatomy.Besides,visual function,orbit and face during childhood are still under development.The orbital deformityes during the childhood,especially for some congenital abnormalities,are always associated with or a cause of visual disfunction.And the congenital or acquired anophthalmia or microphthalm may lead to the retardation of orbital growth and overall of the face afterwards,so it is not only a simple cosmetic surgery for the oculoplastic surgery in the pediatric population,but also the reconstruction of function.Thus we should pay special attention for the oculoplastic surgery to the effect of development of visual function and orbit in the pediatric.Accordingly,it is crucial to select a proper surgical timing and method for ophthalmic plastic surgery in the pediatric.
7.The clinical analysis of ganciclovirum for children infectious mononucleosis treatment
Chinese Journal of Primary Medicine and Pharmacy 2006;0(07):-
Objective To observe the clinical effects and safety of ganciclovirum for children infectious mononucleosis.Methods 56 cases diagnosed children were divided into ganciclovirum group(n=30) and virazole group(n=26) randomly.The two groups accepted ganciclovirum and virazole treatment respectively.The clinical effects and side effects were compared.Results The fever period,the time of lymph node,liver,spleen enlargement,pharyngitis of ganciclovirum group were shorter than those of virazole group.The difference was significant.No obvious side effect was observed during ganciclovirum treatment period.Conclusion Ganciclovirum is more effective and safe for children infectious mononucleosis.
8.Clinical Treatment and Analysis for One Psychosexual Trauma Cases
Chinese Journal of Clinical Psychology 2001;0(03):-
The papers introduced how to deal with and analyse a psychosexual trauma case.The case was mainly caused by childhood experiences of sex trauma and childhood separation anxiety,which resulted in a series of problems such as child barriers,learning disabilities,interpersonal barriers,and affective disorder.Treatment of this case was mainly psychological analysis,integrated use of cognitive therapy,therapy centers and so on.Treatment consisted of three stages: analysis of early experience — understanding and experience-feel self;analysis of medium-term: childhood trauma of separation anxiety,and deal with the shadow of mother.The last stage: touch and face somatization of trauma symptoms,and the psychological trauma.
9.The influence of disease uncertainty on dependency of remedy, shoulder joint movement and ability in daily life in post-operative breast cancer patients
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(11):-
Objective To observe the influence of disease uncertainty ( DU) to patients' compliance with rehabilitation training ( CWRT) , shoulder joint movement (SJM) , and abilities in activities of daily living ( ADL) in post-operative breast cancer (BCPO) patients. Methods Sixty-seven BCPO patients uncertain about their health was assessed using Missals' DU protocol. They were then treated according to the breast cancer rehabilitation training plan recommended by the Japanese Cancer Association. CWRT, SJM and ADL were evaluated before and after treatment. Results The scores on dependency of recovery training, systematic remedy and the ability to change their life style were distinctly higher among patients with low DU scores than among those with high DU scores. The shoulder joint mobility in two groups was similar before the remedy, but became better after treatment. ADL category grades and ADL total scores in the two groups were similar before treatment, and had increased significantly after treatment. The item scores for defecating, diet, dressing and bathing, as well as ADL total scores, were significantly lower in the high uncertainty group. Conclusion DU is one of most important factors for BCPO patients. It can influence CWRT and therapeutic effects in rehabilitation.
10.Clinical analysis of 52 cases of acute pulmonary embolism
Clinical Medicine of China 2008;24(5):451-453
Objective To explore the early characteristics,risk factors and correct diagnosis procedure of acute pulmonary embolism.Methods The onset,axillary examination and susceptibility of 52 cases of acute pulmonary embolism between Jan 2004 and Dec 2005 were analyzed.Results The early manifestation of acute pulmonary embolism was difficulty in breathing,chest pain,hemota and fatigue.Only 11.5%patients presented all the obove symptomes at the same time.D-dimer>500μg/L was 100%.Blood gas analysis showed hypoximia in 94.2%,typical SⅠQⅢTⅢin 13.6% on electrocardiograph,pulmonary artery hypertension in 82.5%on ultrasonography,dilated right in 38.5%of all the subjects.The diagnosis rate was 82.7%at the first diagnosis.Lower limb deep vein embolism,chronic cardiac,kidney disease,malignant tumor and periooperation patients were the risk factors.Conclusion Acute pulmonary embolism is specific-free of clincial manifestation,patients with history of vertigo but excluding difficulty in breathing,chest pain,hemato should go proper examination.