Objective To evaluate the feasibility and safety of uniportal Video-assisted thoracoscopicsurgery(VATS) anatomic segmentectomy for lung diseases.Methods We performed a retrospective review of 52 patients undergoing uniportal VATS anatomic segmentectomy from Mar 2015 to Dec 2015.There were 16 males and 36 females with a mean age of 52.7 years (32-82 years).The incision,about 4 to 5 cm long,is performed at the fourth or the fifth intercostal space.The camera and the instruments are all through the single incision.Results Fifty-one patients underwent uniportal VATS segmentectomy successfully.1 patient with extensive pleural adhesion was needed for auxiliary incision.The median operative time was 125 min (60-240 min),the median blood loss in operation was 60 ml (10-300 ml),the median hospital stay after operation was 4.6 days(2-14 days).There was no perioperative mortality.Major morbidity occurred in 7 patients(13.5％).Pathological examination showed that there were 10 cases of benign diseases and 42 cases of non-small cell lung cancer(26 cases of carcinoma in situ and micro invasive adenocarcinoma,16 cases of infiltrating adenocarcinoma,mucinous adenocarcinoma and carcinoid).Conclusion Uniportal VATS segmentectomy has the advantage of less intercostal nerve injury and good operative perspective.It is a safe and feasible procedure after surgery practice.

National investment in lung cancer related research projects increased during the past few years , the funding from National Natural Science Foundation of China(NSFC) also have an upward trend year by year.As the statistical analysis shows, the NSFC devoted a lot to the projects of lung cancer in both numbers and amounts from 2006 to 2015, and grows rapid-ly.General projects and youth fund projects are predominant types of funds; medical science department is the majority of all departments; Hot research projects include MicroRNA, EMT, lung cancer stem cell, apoptosis, lung cancer genomics,angio-genesis of lung cancer,EGFR, lncRNA, Wnt pathway, etc.The autophagy、lncRNA and Wnt pathway related researchs have gone through the process from scratch, and investments have continued to increase.The purpose of this study is to analyze the distribution and hotspot research of NSFC funded projects in the field of lung cancer in China.