1.The flexible application of image examination in diagnosis of breast diseases
Chinese Journal of Primary Medicine and Pharmacy 2014;(z2):4-6
Objective To investigate the advantage and diagnosis rate of different image examination in breast diseases.Methods From January 2010 to February 2014,all image examination data of 389 breast disease pa-tients who received surgical operation were collected and analyzed retrospectively.All patients underwent color Doppler ultrasound examination.Breast X-ray photographic examination was performed in 325 patients,and MRI ex-amination in 188 patients,while 122 patients received MSCT examination.Results All surgical specimens were ex-amined and diagnosed pathologically.Of all the patients,176 patients were diagnosed with breast cancer(including 117 cases of infiltrating ductal carcinoma,48 cases of mucinous carcinoma,and 11 cases of carcinoma simplex),213 patients were confirmed as benign lesions (including 86 cases of adenomas,35 cases of intraductal papilloma,14 cases of lipoma,26 cases of atypical hyperplasia,34 cases of cystic hyperplasia,3 cases of fibroids,12 cases of adenomyosis, 2 cases of phyllodes tumor,and 1 cases with inflammation).The diagnosis rate with color Doppler ultrasound was 91.0%(354 /389),and the results showed suggestive of malignancy was 75.0%(132 /176 cases).The diagnosis rate with breast X-ray photographic examination was 89.5% (291 /325 cases),and suggestive of malignancy rate was 89.8%(158 /176).The diagnosis rate with MRI was 92.0%(173 /188),suggestive of malignancy was 93.8%(165 /176).The diagnosis rate with MSCT was 91.8% (112 /122),while the suggestive of malignancy was 92.0%(162 /176).Conclusions Both MRI and MSCT have a high diagnostic value than other image examination in discriminat-ing benign and malignant breast diseases.However,there is no difference in diagnosis rate in breast diseases whenever color Doppler ultrasound,breast X-ray photographic examination,MRI or MSCT was used.
2.Relation between sesamoid position of hallux and the function of metatarsophalangeal joints
Orthopedic Journal of China 2006;0(07):-
[Objective]To discuss the alterations of sesamoid position before and after opertation and its relation to the function of the metatarsophalangeal joints.[Methods]Eighty feet(39 hallux valgus feet,41 normal foot) were selected.The distance from sesamoids to the second metatarsal,the relative position of sesamoid bone to the first metatarsal bone,the function of the first metatarsophalangeal joints were determined and analyzed.[Results]The distance from sesamoid to the second metatarsal had no statistical significance in normal feet compared with the hallux valgus feet(P
3.Application of Early Enteral Nutrition on Treatment of Severe Acute Pancreatitis
Chinese Journal of Bases and Clinics in General Surgery 2008;0(08):-
Objective To discuss the feasibility and safety of early enteral nutrition (EN) on treatment of severe acute pancreatitis (SAP) and its influence. Methods The advancement about application of early EN on treatment of SAP in recent years were reviewed. Results In patients with SAP, early EN via catheter placed in the jejunum could protect the integrity of intestinal barrier and reduce infectious complications. But no consensus had been reached about the starting time, ingredient and infusion mode yet. Conclusion Early EN may have positive effects on treatment of SAP, but further researches are still needed.
4.Distribution and characters of peptide YY receptor in rat jejunum epithelial cell
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(01):-
Objective To detect normal rat jejunum epithelial cells to learn about the distribution of peptide YY(PYY)receptor and measured two important parameters of PYY receptor so as to explore the target that PYY binds to and display its physiological function.Methods Receptor radioligand assay was conducted by using 125I-PYY to detect normal rat jejunum epithelial cells.We also measured receptor dissociation constant(Kd),the affinity or the ability that the receptor could bind ligand;maximum binding capacity(Bmax),the concentration of binding site;and Hill coefficient.Results There were PYY receptors in normal rat jejunum epithelial cells.Dissociation constant(Kd)of PYY receptor was(386.69?129.95)pmol/L.Maximum binding capacity(Bmax)was(303.21?116.85)fmol/mg protein.Hill coefficient was 1.PYY receptor had high affinity.Conclusion There are distributions of PYY receptors in normal rat jejunum epithelial cells.Kd means that PYY receptor has high affinity.Bmax means that the number of receptors is limited and decides the characters of saturability.We think that PYY directly inhibits secretion by binding to PYY receptor in jejunum epithelial cells when PYY inhibiting jejunum secretion.
5.Dynamic MR imaging of intrahepatic peripheral cholangiocarcinoma
Chinese Journal of Radiology 2000;0(11):-
Objective To evaluate the dynamic MR imaging findings of peripheral cholangiocarcinoma (PCC) of the liver. Methods Seventeen patients with PCC underwent dynamic MRI during the early, middle, and delayed phase after contrast medium administration. Enhancement pattern of the tumor, the wedge-like enhancement area peripheral to the tumor, dilatation of the intrahepatic biliary ducts, vascular involvement, and extrahepatic tumor invasion were evaluated. Results Early peripheral enhancement with progressive and concentric filling by contrast medium was the most frequent enhancement pattern (9 patients). A wedge-like enhancement area was observed in 10 patients. Ductal dilatation was found in 11 patients. Vascular involvement and extrahepatic invasion were seen in 8 and 2 patients, respectively. Conclusion Enhancement pattern is relative to the character of pathology (quantity and distribution of cell and fibrosis). Early peripheral enhancement with progressive and concentric filling by contrast medium may be specific for PCC.
6.Classification of symptoms and signs in clinical term system of traditional Chinese medicine
Chinese Journal of Medical Library and Information Science 2015;24(10):77-80
After the concept of symptoms in traditional Chinese medicine was defined, the classification of symp-toms in traditional Chinese medicine and the characteristics of clinical diagnosis and treatment in traditional Chinese medicine were described .It was suggested that the symptoms in traditional Chinese medicine should be classified into 3 kinds, namely symptoms and signs according to the 4 diagnostic methods, symptoms and signs according to the diagnostic devices, symptoms and signs according to the physical constitutions of patients in order to lay a foun-dation for improving the classification in clinical term system of traditional Chinese medicine.
7.Clinical study on moxibustion combined with pressing beans on auricular point in the trentment of elderly patients with chronic diarrhea
Chinese Journal of Primary Medicine and Pharmacy 2013;20(13):1924-1925
Objective To observe the efficacy of the combination of moxibustion and pressing beans on auricular in the treatment of elderly patients with chronic diarrhea.Methods 45 elderly patients met the diagnostic criteria for diarrhea were divided into two groups,the treatment group (23 cases) received the treatment of combined moxibustion with ear pressure beans,the control group (22 cases) received traditional Chinese medicine treatment.The efficacy was observed and compared after two weeks.Results The effective rate reached 95.6% in the treatment group,81.8% in the control group (statistically significant difference,odds ratio 1.16).Conclusion Combined ear pressure beans with moxibustion treatment will receive a significant effect for the elderly patients with chronic diarrhea.The therapy is worth clinical application.
8.Super-antioxidant activity of natural astaxanthin and its application
Chinese Journal of Marine Drugs 1994;0(04):-
The source, super-antioxidant activity, biological safety and application in medicine, health food and animal feed industry of natural astaxanthin are reviewed in present paper. The industrialization prospect of astaxanthin in China is also proposed.
9.Status quo and Countermeasures of Medical Equipment in Use and Maintenance
Chinese Medical Equipment Journal 2003;0(10):-
This paper expatiates and analyzes the various problems in the course of using and maintaining the medical equipment in hospital.It also puts forward some substantive countermeasures to solve the problems such as training for operators,setting of management regulations,broadening the position and team construction of qualified personnel in medical engineering,etc.
10.Research the expression of NF-?B and apoptosis of neutrophils induced by TNF-? treated with Lidocaine
Chinese Journal of Clinical Pharmacology and Therapeutics 2004;0(12):-
AIM:To observe the effect of lidocaine to the activation of NF-?B and apoptosis in human neutrophils(PMN)in vitro.METHODS:Human PMN were divided into five groups:control group(0.9% sodium chloride);TNF-?(200 ng/L);TNF-?+lidocaine(1.0 mmol/L);TNF-?+lidocaine(2.0 mmol/L),and TNF-?+ lidocaine(4.0 mmol/L).The expression of NF-?B subunit p65 mRNA in the nuclear and I-?B mRNA in the cytosol extracts were analyzed by Western blotting,after co-incubation for 3 h and the content of p65 protein were observed by RT-PCR.PMN apoptosis was detected on flow cytometry after co-incubation 12 h and 24 h.RESULTS:The expression of NF-?B mRNA was significantly decreased and the expression of I-?B mRNA was markedly increased in lidocaine groups(P