Objective To investigate the prevention effect of auto-crosslinked hyaluronic acid gel on re-adhesion for patients with moderate to severe intrauteriae adhesion (IUA) after hysteroscopy surgery. Methods 92 patients with moderate to severe IUA underwent hysteroscopy surgery from June 2013 to December 2014 were enrolled for the study and randomly divided into observation group and control group, 46 cases in each group. Patients in control group were given Foley balloon catheter to intrauterine after operation. Based on it, patients in observation group were given auto-crosslinked hyaluronic acid gel. American fertility society (AFS) IUA score, effective prevention rate and incidence of moderate to severe IUA in 3 months after operation were compared between the two groups. Results The scores of adhesive type and menstrual pattern and total AFS score of observation group in 3 months were significantly lower than that in control group (P <0.05). Effective prevention rate of observation group was sig-nificantly higher than that in control group, and the incidence of moderate to severe IUA was significantly lower than that in control group, the differences had statistical significance ( P<0.05). Conclusions Auto-crosslinked hyaluron-ic acid gel could effectively prevent the happening of re-adhesion in patients with moderate to severe IUA after hys-teroscopy surgery. It is safe and reliable, worthy of clinical popularization and application.

Objective:To analyse ZHOU Zhong-ying’effective combination drugs in preventing and treating the systemic lupus erythematosus(SLE).Methods:Association rules based on Chi-squared analysis and influence degree was used.Results:73 Rules of TCM couples were selected in the high frequency drugs distribution,and the drugs were mainly those for heat clearing,antidote medicines and blood act stasis remove medicines,which was in accordance with the main pathological mechanism factor for SLE given by Professor Zhou.Conclusion:The new method could find out many significant TCM couples in the study of the compatibility of TCM.

OBJECTIVE:To evaluate the efficacy and safety of Yupingfeng powder combined with second- generation antihistamines versus second-generation antihistamines for chronic urticaria(CU)systematically,and to provide evidence-based reference for clinical treatment for CU. METHODS:Retrieved from PubMed,Embase,The Cochrane Library,CJFD,VIP and CBM,RCT about therapeutic efficacy(total response rate,cure rate,recurrence rate)and safety(the incidence of ADR)of Yupingfeng combined with second-generation antihistamines(trial group)versus second-generation antihistamines(control group) in the treatment of CU were collected. The data extraction was performed for included clinical studies,and Meta-analysis was performed by using Rev Man 5.3 statistical software after quality evaluation with Cochrane Handbook 5.1.0 evaluation criteria. RESULTS:A total of 34 RCTs were enrolled,involved 3 405 patients in total. Results of Meta-analysis showed that the total response rate [OR=4.02,95%CI(3.03,5.34),P<0.001],cure rate [OR=2.25,95%CI(1.95,2.60),P<0.001] and recurrence rate [OR=0.33,95%CI(0.26,0.42),P<0.001] of trial group were significantly better than those of control group,with statistical significance. There was no statistical significance in the incidence of ADR between 2 groups [OR=0.98,95%CI(0.71,1.37),P=0.92]. CONCLUSIONS:For CU therapy,Yupingfeng powder combined with second-generation antihistamines is better than second-generation antihistamines alone in improving total response rate and cure rate,reducing recurrence rate,both have similar safety.