1.Histopathology and immunohistochemical study in the classification of lymph node lesions
Huong Duc Tran ; Roanh Dinh Le ; Hoe Dinh Le ; Chu Van Nguyen
Journal of Medical Research 2007;49(3):35-40
Background: Large lymph-node is clinically common sign. However, in some cases, it is difficult to diagnosis by staining method routinely. Objectives: To classify of lymph node lesions by histopathological and immunohistochemical study. Subjects and methods: 1860 cases carried out lymph node biopsies at K Hospital were histologically and immunohistochemically analyzed. Results: The most common lesions were lymph node metastasis (35.25%) chronic lymphnoditis (20.82%), tuberculous lymphnoditis (19.42%) and non Hodgkin lymphoma (18.62%). Histological typing of metastasis revealed that the most frequent types were undifferentiated carcinomas (28.13%), squamous carcinomas (23.7%), adenocarcinomas (16.97%) and type-unspecified carcinomas (13.3%). Non Hodgkin lymphoma rate was higher than that of Hodgkin lymphoma (86.06% versus 12.8%). Immunopheotype of non Hodgkin lymphomas showed that 79.71 % were B cell type, 18.15% were T cell type and 2.14% were Ki-1 type. The most common types of B cell lymphomas were diffuse large B cell lymphomas (35.57%), follicular lymphomas (25.9%) and diffuse small B cell lymphomas (13.83%), The most common types of T cell lymphomas were lymphoblastic T cell lymphomas (41.8%)., large T cell lymphomas (23.53%) and unspecified periphery T cell lymphomas (11.76%). Conclusion: Immunohistochemical analysis of metastasis allowed identifying immunophenotypes of different types of metastatic carcinoma and melanoma and evaluating the origin of unknown primary metastasis. \r\n', u'\r\n', u'\r\n', u'
Immunohistochemistry
;
Lymphadenitis
;
Lymphoma
2.Primary result of building a street food safety and hygiene model in Hue city
Hong Xuan Duong ; Son Dinh Nguyen ; Hoa Thai Nguyen ; Dam -- Tran ; Nam Huu Hoang ; Oanh Dinh Tran ; Linh Van Bach
Journal of Preventive Medicine 2007;17(4):27-32
Background: Hue city is a cultural and tourism center of The middle and the whole country. Beside developing tourism services, food processing establishments, traditional specialities, eating and drinking services especially street food services more and more develop plentifully and multiform, satisfy daily demand of consumers. Objectives: Assessment on improvement level on some targets of street food safety and hygiene after 2 years intervention. Subjects and method: All street food processing establishments in 3 wards: V\u0129nh Ninh, Ph\xfa H\u1ed9i, V\ufffd?D\ufffd?of Hue city. Method: Cross-sectional study with comparison before and after intervention. Results: Kitchen utensils samples have met hygiene requirements and the proportion of food samples without borax both increase. The infection rate of bacteria in cook\ufffd?hands, kitchen utensils, cooked food were improved after 2 years carried out targeted model. Clean water for processing street food have not enough although 100% households use running water. The proportion of people were trained about food safety and hygiene knowledges and health examination increase. The situation of using food colourings and poisonous additives decrease remarkably. Salesclerks have more consciousness of preserving and covering food. 86,4% of food processing establishments have recycle bins obtain requirement to reduce polluted food. Conclusion: Street food is an important stage of food supplying network in 3 wards above. Somewhere having interest of Government and local authorities, Steering committee have efficient activities street food model develop conveniently.
Food Safety/ methods
3.Histological classification of lymph node malignant non-Hodgkin lymphoma based on the new WHO 2001 classification.
Huong Duc Tran ; Roanh Dinh Le ; Hoe Duc Le ; Chu Van Nguyen
Journal of Medical Research 2007;47(2):38-44
Background: Non-Hodgkin's lymphoma is a malignant (cancerous) growth of B or T white blood cells (lymphocytes) in the lymph system. Many lymphoma classifications were proposed. All were based by groups of the original cells, histopathological appearances and clinical features. Purpose: Histological classification of lymph node malignant non - \r\n", u'Hodgkin lymphoma based on the new WHO 2001 classification. Objectives: To apply new WHO 2001 classification of 165 cases of malignant non Hodgkin lymphoma were histopathologically and immunohisto chemically studied at K hospital in Hanoi. Subjects and method: The study included 165 patients with malignant non Hodgkin lymphoma were examined and treated at K hospital in Hanoi from 2000 to 2003. Results: The study based on new WHO 2001 classification of 165 cases of malignant non Hodgkin lymphoma showed results B lymphoma: Diffuse large B - cell lymphoma accounts for 63.3%, follicular lymphoma: 17.5%, small lymphocytic lymphoma: 12.5%, mantle cell lymphoma: 1.7% and the others are at low rate. T lymphoma: large T-cell lymphoma accounts for 35.0%, T lymphoblastic lymphoma: 30.0%, angioimmunoblastic T-cell lymphoma: 12.5%, peripheral T- cell lymphoma, unspecified: 10.0%, the others are at low rate. Conclusion: We concluded that new WHO classification of malignant non Hodgkin is reproducible in our practice and should be useful in the treatment decision. \r\n', u'
Lymphoma
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Non-Hodgkin/ pathology
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epidemiology Neoplasms by Histologic Type
4.The epidemic of Dengue Fever/Dengue Haemorrhagic Fever (DF/DHF) in Khanh Hoa province in the year 2005
Hai Van Nguyen ; Mai Thi Tuyet Tran ; Luu Dinh Duong ; Xuan Thanh Dang ; Trong Thi Luong
Journal of Preventive Medicine 2008;18(2):32-38
Background: In Vietnam, Dengue Fever/Dengue Haemorrhagic Fever (DF/DHF) is one of ten contagious diseases causing epidemics with the highest prevalence.\r\n', u'Objectives: To describe some characteristics of DF/DHF epidemic in Khanhhoa province in 2005. \r\n', u'Subjects and methods: The descriptive study based on available data obtained from the surveillance reporting system.\r\n', u'Results: Total reported cases were: 5.365 (morbidity rate = 469.58 per 100.000) and 4 deaths (CFR = 0,074%).446 of 1.661 Mac Elisa tested cases were positives (positively = 26.9%). The positive cases in male were higher than that in female. Almost all of the positive cases were less than 15 years of age. Virus serotype D1 and D2 were isolated in the epidemic. 5 of 7 districts (except 2 mountainous districts) had outbreaks. The epidemic started in April and stopped in December. Ninhhoa district was the first location of the outbreak and Vanninh district was the last one. Geographical distribution of the epidemic was as follows: costal communes=54.6%, delta communes = 30.3%, urban communes =15.1%. The epidemic level was medium (>20% - <50% of communes having the epidemic). "Pilot intervention communes" had 4 times the higher risk of DF/DHF than "non pilot intervention communes". \r\n', u'Conclusions: IEC activities for preventing DF/DHF should be strengthened. For maintaining the low mosquito and breutau index, we need routine preventive actions. Authorities need to consider and to consolidate the activities of Pilot intervention communes. Coastal communes should be supplied with running water. \r\n', u'\r\n', u'
dengue fever/dengue haemorrhagic fever
;
epidemic
5.Remarks on food safety and hygiene at Thua Thien Hue province (1992 - 2006)
Hoa Thai Nguyen ; Son Dinh Nguyen ; Dam Tran ; Hong Xuan Duong ; Hao Van Huynh ; Loc Danh Tran
Journal of Preventive Medicine 2007;17(4):22-26
Background: At present, management and supervision on food safety and hygiene quality have many difficulties because supervisory system from province to district, commune is still insufficient. Objectives: Assessment on food safety and hygiene situation at Thua Thien Hue province, propose solutions to intensify State management on food safety and hygiene quality and step by step enhance efficiency of food safety and hygiene activities in the next years. Subjects and method: Food processing establishments at Thua Thien Hue province. Method: Inspection in Action months for food safety and hygiene, supervision usually on food processing establishments were chosen accidentally in area. Food samples were inspected indexes of microorganisms, physicochemical have met the criteria of Ministry of Health. Results: The proportion of food processing establishments and cafeterias which have not met the regulations on food safety and hygiene was decreasing from 40,93% to 27,45%. Also in 2002-2006, 36,71% of kitchen utensils and the cooks\ufffd?hands failed to meet the regulations. Regarding to microorganisms, the indices of ice-cream, bean sweet porridge and soft drinks had improved remarkably. The index of ice had been decreased from 33,02% to 22,56%. 45,25% of bowls and plates didn\u2019t meet chemical and physical criteria. 68,4% of food colourings didn\u2019t meet criteria because inorganic and industrial colourings were used. Traditional foods still contain borax although the prevalence is decreasing from 65% to 35%. Ice cream and bean sweet porridge cooked with saccharine were 37,34%. Conclusion: Understanding of producers and consumers about food have still many limitations.
Food Safety/ methods
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6.Epidemiological characteristics of HIV/AIDS patients and community care in Thua Thien Hue
Ngoc Thi Tran ; Son Dinh Nguyen ; Minh Quang Duong ; Hoa Thai Nguyen ; Tam Le Nguyen ; Son Van Ly ; Son Huu Le ; Dung My Tran ; Hao Van Huynh
Journal of Preventive Medicine 2007;17(4):39-44
Background: HIV/AIDS pandemic really become danger to mankind on the earth. Objectives: Description epidemiological characteristics of HIV/AIDS patients. Studying clinical expression, learning aboutdemands of infected patients and community care for infected patients. Subjects and method: 71 HIV/AIDS people in Thua Thien Hue were studied in 2006. Using descriptive method to give epidemiological characteristics and behaviour of HIV/AIDS people. People were determined HIV/AIDS infection based on the criteria of Ministry of Health. The information were collected by target study. Results: HIV/AIDS people mainly from the age of 20 to 39 (83,10%), males were 52,10% and in various levels of education and all kinds of occupation. The rate of sexually transmitted infection was 84,5% and infection transmission was 15,5%. The rate of sexually transmitted infection within the last 12 months was 57,7%. 63,4% of infected people used condom while having sex with their spouses or partners. 1,4% of infected people using drug infection within the last month. 38% of the infected people had manifestations of AIDS, 77,8% of HIV/AIDS were treated with antiviral drugs. Families and communities had positive attitudes and behaviors to the HIV/AIDS people. Infected people being remoted from the society was 12,7%, 88,7% of them receiving supports from their communities such as disease treatment, spirit and material supports and job opportunities. Conclusion: Strengthen communication activities to change behavior of HIV/AIDS people and in communitiy to reduce alienation, discrimination for infected people. Execute socialization in care and support for HIV/AIDS people.
HIV/ immunology
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isolation &
;
purification
;
pathogenicity
;
Community Health Services/ organization &
;
administration
;
Epidemiologic Methods
;
7.Performance and kap of army medical officers at the border area
Son Dinh Nguyen ; Hoa Thai Nguyen ; Dung Nguyen ; Nhien Dai Tu Vo ; Hao Van Huynh ; Loc Danh Tran
Journal of Preventive Medicine 2007;17(4):5-11
Background: The combination medical between army and pepople in protection, healthcare for people and army in the whole country was a great policy of The Party and State. Objectives: Evaluate result of combination between armed forces in epidemic control and preventive medicine programs at mountainous and coastal areas of Thua Thien Hue in 2006. Studying knowledge, attitude, practice of army medical officers and men canvassed masses about epidemic control and preventive medicine programs. Subjects and method: Officers, men, army medical officers in 41 communes (28 coastal communes and 13 mountainous communes) of 5 district have combination medical between army and pepople. Using epidemiology method to description, analysis, cross-sectional study. Results: In 2006, home-flies spraying was carried out in 18 out of 20 markets; 1,030 all size restaurants and 18 residential areas of 5 districts. The number of chemically treated latrines in high epidemic areas was accounted fof 15,1%. A population-based latrine construction project was initiated to build 838 new latrines, contributing to minimize the invironmental pollution. 9,17% of waterwells and water tanks were hygienically treated; 11,434 people used clean water source; and 46,436 people washed their hands with soap. Studying knowledge, attitude, practice on preventive medicine programs of army medical officers showed very good results. Conclusion: The combination medical between army and pepople in preventive medicine, epidemic control gave wide efficiency for mountainous and coastal communes of Thua Thien Hue. It actively supported for Health station of 28 coastal communes and 13 mountainous communes in preventive medicine work.
Community Health Services/ ethics
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manpower
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Health Knowledge
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Attitudes
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Practice
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8.Application of microplate almar blue assay for rapid detection of drug resistance of M. tuberculosis strains
Ly Minh Ho ; Hoa Thanh Tran ; Lien Kim Pham ; Hung Van Nguyen ; Phuong Thi Hoang ; Sy Ngoc Dinh
Journal of Preventive Medicine 2008;0(3):60-66
Background: Recently, microplate almar blue assay has been used commonly in detecting gen related to tuberculosis drug resistance, which provides results after 5-7 days with lower cost compared to traditional methods. Objective: To evaluate the application of microplate almar blue assay for rapid detection of drug resistance of M. tuberculosis strains. Subject and Method: A microplate-based assay which uses Alamar blue reagent - an oxidation reduction dye (MABA), was used for the determination of the anti-tuberculosis drug (isoniazid-INH, rifampicine-RIF, streptomycine-STR and ethabuton=EMB) resistance of 96 M. tuberculosis strains isolated from Vietnamese patients in comparison to those obtained by conversional method. Result: MABA showed to have high sensitivity and specificity in testing the sensitivity to individual anti-tuberculosis drugs (from 82.4% for STR to 93.3% for - INH and from 82.5% for EMB to 98.4% for STR; respectively), as well as for the multi-drug resistant M.tuberculosis (86.4% of sensitivity), highly correlated with the result determined by proportion method. Conclusion: MABA reveals the advantage in shortening test time, in simple performance and lower cost compared with the conversional culture based methods.
Microplate almar blue assay
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M. tuberculosis
;
drug resistance
9.Assessment of child health care practices in Tu Liem district, Ha Noi and Tien Hai district, Thai Binh province
Mai Thi Phuong Le ; Thuy Thi Thanh Nguyen ; Quyet Tu Nguyen ; Dinh Van Tran ; Dung Phuong Luu
Journal of Preventive Medicine 2008;96(4):43-48
Background: Child health care practices in the context of households and community is an important factor to improving the health of children. Some indexes were proposed by the World Health Organization to evaluate these practices. Objectives: To describe the knowledge and practice of pregnant women, under-5-year-old children\u2019s health care and assess the application of the survey toolkit in evaluating various indexes of healthcare practice at family and community levels. Subjects and method: By employing a structured interview, this cross-sectional survey has been conducted in Tu Liem district - Hanoi city and Tien Hai district \u2013 Thai Binh province. 120 mothers of under-5-year-old children participated in the survey. Results:98% of mothers had at least 3 antenatal visits during pregnancy. The rate of complete tetanus vaccination reached 43.3% in Tu Liem and 65% in Tien Hai. Prevalence of infant with low birth weight for age accounted for 8.3% in both districts. The percentage of children given complementary feeding at age of 6 to 9 months as the National Nutrition Program recommendations was only 30%. 65.7% and 68.5% of under-2-year-old children in Tu Liem and Tien Hai were breastfed within the first 30 minutes after delivery. There were a small proportion of mothers who gave complementary food either too early or too late, 8.3% and 8.4% in Tu Liem, 6.7% and 6.6% in Tien Hai, respectively. More than 90% of children were given normal feeding as usual during last their illness, but only 50% of children were given more fluid than usual. 98.2% of mothers knew 2 signs to immediately bring the child to health facilities. The most common injuries in under-5-year-old children were animal bites (62.5%) and falling (31.3%), however only 62.5% of mothers knew at least two measures of injury prevention. Conclusion: The toolkit for collecting data of practical index assessment can be applied at communes.
child health care
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practice
;
knowledge
10.The situation of HIV/AIDS infection of prisoners at Binh Dien prison from 2005-2006
Tam Le Nguyen ; Minh Quang Duong ; Hue Thanh Dinh ; Son Dinh Nguyen ; Ngoc Thi Tran ; Hoa Thai Nguyen ; Son Van Ly ; Son Huu Le ; Dung Thi My Tran ; Hung Chi Nguyen
Journal of Preventive Medicine 2007;17(4):45-50
Background: With the development of HIV/AIDS pandemic in community, amount of HIV/AIDS people more and more increase in prison. Objectives: Determine the rate of HIV/AIDS infection of prisoners at Binh Dien prison. Learning about related elements to HIV/AIDS infection. Subjects and method: Prisoners at Binh Dien prison. Method: 492 prisoners were chosen, interviewed directly and taken blood samples to HIV test. Using cross-sectional study on accidental samples. Techniques were used in this study: SERODIA-HIV and ELISA technique. Results: The rate of current HIV/AIDS infections was 21,74%, some HIV/AIDS related factors in the prison included sex, religion, income source, marrital status, common knowledge of HIV/AIDS, drug addiction history, needle sharing, sexually transmitted disease history, body tatoos and forskin inserted with metal balls, alcohol and beer drinking history, some factors such as: age and educational level were not associated with HIV/AIDS infection in prison. Conclusion: Strengthen interventional activities in prison to prevent HIV/AIDS spread between prisoners. To prisoners who were not infected HIV/AIDS: strengthen educational communication to they may prevent themselves from HIV/AIDS infection behaviors. To HIV/AIDS prisoners: Need to educate and consult especially to they have right behaviors, prevent HIV/AIDS spread for the others while they were in prison as well as they return to society.
HIV Infections/ blood
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complications
;
epidemiology
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