Due to the latent and highly invasive characteristics of liver carcinoma,a majority of patients are frequently not diagnosed until moderate or advanced stage in the disease process,and usually complicate with cirrhosis.Only 15％ -30％ of the patients are eligible for radical resection.The overall survival time is about 3-4 months.Therefore,on the basis of early diagnosis and treatment of liver carcinoma,how to improve the treatment effect of the moderate and advanced liver carcinoma,ameliorate the quality of life and prolong the survival time,becomes the focuses and difficulties both at home and abroad.

To introduce composition,the testing principle of the urine analyzer,To reduce the failure rate, extend the service life of the instrument and improve the accuracy of diagnosis. Make the maintenance system ,according to the system of equipment maintenance maintain the urine analyzer daily and monthly. The maintenance plays an important role in reducing the failure rate, extending equipment life and improving the accuracy of diagnosis.

Objective To observe the clinical efficacy of combining Yuan-Primary and Luo-Connecting points in treating insomnia due to imbalance between heart and kidney, for providing novel method and evidence for the treatment of insomnia with acupuncture-moxibustion.Method Totally 100 insomnia patients due to imbalance between heart and kidney were randomized into a treatment group and a control group, 50 in each. The treatment group was intervened by acupuncture at Yuan-Primary and Luo-Connecting points, while the control group was by conventional acupuncture. The Pittsburgh Sleep Quality Index (PSQI), self-rating anxiety scale (SAS), and self-rating depression scale (SDS) were observed before and after intervention for efficacy evaluation.Result The PSQI item scores were significantly changed after intervention in both groups (P<0.05). The SAS and SDS scores were significantly different from that before treatment in both groups (P<0.05). After treatment, the SAS and SDS scores of the treatment group were significantly different from that of the control group (P<0.05). The recovery rate and total effective rate were 26.0% and 92.0% in the treatment group versus 12.0% and 86.0% in the control group, and there was a significant difference in comparing the recovery rate (P<0.05).Conclusion Combining use of Yuan-Primary and Luo-Connecting points is an effective approach in treating insomnia due to imbalance between heart and kidney.

?Objective: To evaluate the mechanical properties of low noble alloy Au Pd and Ag Pd developed by Stomatological College,Fourth Millitaly Medical University and Xi'an University of Architecture & Techuology. Methods:The two low noble alloys were cast by means of a centrifugal induction furnace into the tensile bars whose dimensions accorded with the standards of China for Dental Casting Precious Metal Alloys. Tensile properties (?b)were determined by means of a conventional testing machine. The 0.2% offset yield strength(?0.2), elongation(?) and microhardness (HV)were determined in a conventional manner. All data were the average of four specimens of each alloy. Results:?b(MPa),?0.2(MPa),?(%) and HV of Au Pd were 485?12.9,365 ?14.8,7.8?1.1 and 220?14.3;those of Ag Pd 550?9.5,435?8.2,13.5?5.4 and 245?15.1,respectivey.Conclusion:The mechanical properties of the two low noble alloys meet the demands of standards and have lower microhardness than natural tooth enamel.

Objective To compare the contents of Ferulic Acid and Polysaccharide in Angelica Sinensis oliv. with Lotiform Angelica sinensis because of the morphosis related to lateral bud of Angelica Sinensis. Method The contents of Polysaccharide was determined by Polysaccharide-Phenol-Sulfuric acid reaction system. The content of ferulic acid was determined by HPLC. Result There is no significantly difference in the contents of Ferulic Acid and Polysaccharide between Angelica sinensis and lotiform Angelica sinens. Conclusion The contents of Ferulic Acid and Polysaccharide between Angelica Sinensis oliv. and Lotiform Angelica sinensis has no significantly difference because of the morphosis related to lateral bud of Angelica Sinensis.

A union operation method of chromatograph mass spectrometer was applied in analyses of volatile oil compositions in flowers and leaves of Radix Ginseng. The preliminary identification indicated thai there were 15 and 32 kinds of chemical compositions in flowers and leaves of Radix Ginseng, respectively. Meanwhile, their relative content has also been determined.

Objective To study the chemical constituents from the roots of Zanthoxylum nitidum.Methods The constituents were isolated and purified by column chromatography.Their structures were identified on the basis of physiochemical properties and spectral data.Results Two benzophenanthridine alkaloids,1,3-bis(8-dihydronitidinyl)-acetone(1)and 8-acetonyldihydrofagaridine(2),have been iso-lated from the roots of Z.nitidum.Conclusion Compounds 1 and 2 are new compounds named nitidumtone A and nitidumtone B.

Endomyocardial Fibrosis ; Fibroblasts ; Humans ; Myocardium ; pathology

Resveratrol,which is produced by natural plants,has various biological activities,including anti-inflammatory,antioxidant and anticancer properties.Recently,it is found that resveratrol can inhibit the proliferation and promote the apoptosis of breast cancer through multiple molecular targets,which provides a theoretical basis for resveratrol used in the treatment of breast cancer.

Objective To investigate the significance of metastasis associated lung adenocarcinoma transcript 1 (MALAT1) in the occurrence and development of non-small cell lung cancer(NSCLC).Methods Eighty-six NSCLC lung tissue samples and 86 corresponding adjacent tissues were collected.Real-time quantitative polymerase chain reaction (RT-PCR) was used to detect MALAT1 mRNA expression.The correlation analysis of the gender,age,carcinoma embryonic antigen (CEA),clinical stage,and the degree of differentiation was performed.Results MALAT1 expression levels showed an average 2.16-fold increase in NSCLC lung tissues(87.23 ±9.72) when compared with adjacent tissues(40.38 ± 5.49),the difference was statistically significant (t =7.894,P ＜ 0.01).There was no significant difference between gender,age,histological type,tumor diameter,CEA level in terms of MALAT1 expression (P ＞ 0.05).There was significant differences between pathological stage (Ⅰ stage =52.38％ (11/21),Ⅱ stage =76.00％ (19/25),Ⅲ stage =97.50％ (39/40),x2 =11.839,P =0.042),tumor differentiation (High differentiated =39.13％ (9/23),moderately differentiated =74.47％ (35/47),low differentiated =100％ (16/16),x2 =15.383,P =0.032)and lymph node metastasis (with =97.22％ (35/36),no =46.00％ (23/50),x2 =23.947,P =0.030).Conclusion MALAT1 might be involved in the development of NSCLC,and could be an auxiliary diagnosis marker.