Toll-like receptor (TLR) plays a crucial role in innate immune response and the subsequent induction of adaptive immunity. TLR is expressed on immune cells as well as epithelial cells and tumor cells. When endogenous and exogenous ligands bind with TLR, TLR signaling pathways are activated and a large number of inflammatory cytokines are released, creating an inflammatory microenvironment and leading to tumor formation, invasion and metastasis.

By classification with syndrome differentia -tion into the three patterns of deficient cold in the lower energizer, qi deficiency in the spleen and lung and damp heat in the Liver Meridian, 43 cases of enuresis were treated by puncturing Baihui (GV 20), Guanyuan (CV 4)and Sanyinjiao (SP 6). After two courses of the treatment,the results showed cure in 28 cases, improvement in 13 cases and failure in 2 cases.

Objective To optimize the extraction conditions for Yuemu eye drops.Methods The extraction conditions were studied with orthogonal test L_9(3~4),the content of caffeic acid was determined by HPLC as index.Results Alcohol concentration and frequency of extraction were remarkable factors in the test. Conclusion The optimum extraction technology for Yuemu eye drops was to reflux and extract the materials for 2 times in 80% alcohol,the volume of which was 6 times the weight of herbal medicine,with 1 hour for each time.

OBJECTIVE:To establish sodium tetraphenylborate volumetric method in place of gravimetric analysis method for the determination of the content of potassium chloride in compound sodium chloride injection.METHODS:The contents of potassium chloride in compound sodium chloride injection were determined by sodium tetraphenylborate volumetric method and sodium tetraphenylborate gravimetric method respectively,the results of which were compared.RESULTS:The average recovery of volumetric method was99.75%(RSD=0.46%,n=9),there was no significant difference in the t-test comparison between the determination results of volumetric method and that of the gravimetric method.CONCLUSION:The sodium tetraphenylborate volumetric method is simple,fast and accurate,which can take the place of gravimetric method for the deter?mination of contents of potassium chloride in compound sodium chloride injection.

0.05),but there were more side-effects in study group(P

ObjectiveTo compare the clinical effect and security of Reparil Gel on osteoarthritis of the knee.Methods60 patients were randomly divided into Reparil Gel group and Fenbid group, who applied Reparil Gel or take Fenbid orally respectively. Western Ontario and McMaster University Osteoarthritis Index (WOMAC) was used to assess patients' pain, joint stiffness and disability of knee on 0 week, 2 week, 6 week after treatment. The side effect was observed.ResultsBoth group showed good clinic effect on 2 weeks (P<0.05)and 6 weeks (P<0.001)after treatment. Significant difference between two group was found 2 weeks after treatment, but there was no difference 6 weeks after. There was no side effect had been observed in Reparil Gel group, while stomachache, nausea or anorexia had been found in 4 case of Fenbid group 2 weeks after, and 8 case of Fenbid group 6 weeks after.ConclusionReparil Gel are same effective as Fenbid, but less side effect happened.

Adolescent ; Adrenergic beta-Agonists ; therapeutic use ; Albuterol ; analogs & derivatives ; therapeutic use ; Asthma ; drug therapy ; physiopathology ; Child ; Child, Preschool ; Female ; Forced Expiratory Volume ; drug effects ; Humans ; Male ; Salmeterol Xinafoate

Child ; Congresses as Topic ; Humans ; Pediatrics ; Sleep

Child ; Humans ; Vesico-Ureteral Reflux ; therapy