1.Effect of ultraviolet rays and mechanism of injury to eyes
Chinese Journal of Radiological Medicine and Protection 2016;36(2):149-153
With continued ozone deletion and increased ultraviolet application,ultraviolet (UV) induced eye injury receives more attention,especially for astronauts,residents on high elevation plateaus and other people exposed to intense beams of UV.Continuous exposure to UV can lead to damage of conjunctiva,cornea,crystalline lens and retina,which are correlated with conjunctivitis,keratitis,ocular tumor,climatic droplet keratopathy,and pterygium.This paper focuses on the effect of UV on eyes,with a systematic elaboration of UV-induced eye injury.
2.Non-skeletal actions of vitamin D
Chinese Journal of Clinical Nutrition 2009;17(4):246-250
non-skeletal actions,including immunoregulation,anti-tumor effect,and protecting from central nervous system diseases and metabelie syndrome.
3.Efficacy and safety of dipeptide base peptidase 4 inhibitors combined with metformin combination therapy in type 2 diabetes
Ran DING ; Guocong DING ; Rihong CAI
Chinese Journal of Biochemical Pharmaceutics 2016;36(12):154-156,159
Objective To evaluate the clinical efficacy and safety of dipeptide base peptidase 4 ( DPP-4 ) inhibitors alone or combined with metformin in curing type 2 diabetes mellitus (T2DM).Methods 90 patients diagnosed with type 2 diabetes in Tangshan Fengrun District Hospital and Tangshan Checheng Hospital were selected and randomly divided into therapy group ( DPP4 inhibitor ) , control group ( metformin ) and combination therapy group with 30 cases in each group.And treatment for three months, the free blood glucose (FPG), 2-hour postprandial blood glucose (2hPG), glycated hemoglobin (HbA1c) levels and other indicators were compare before and after treatment, and the rates of hypoglycaemia and adverse events during treatment were monitored and counted.Results After 3 months of treatment, the free blood glucose, 2-hour postprandial blood glucose, LDL-C and HbA1c levels were significantly decreased, the difference was statistically significant (P<0.05) while the combination therapy group compared with the the therapy group and control group with better results.The incidence of side-effect in the combination therapy group is significantly lower than the therapy group and control group, the difference was statistically significant (P<0.05).It is no cases of hypoglycemia occurs in the combination therapy group, and had a smaller effect on BMI.Conclusion DPP-4 inhibitors combined with metformin in patients with type 2 diabetes has better efficacy and safety.
4.Effect of Parallel Scalp Acupuncture Therapy on Hemodynamic Function of Cerebral Circulation in Post-stroke Patients
Li LI ; Jianqiu GONG ; Guanghong DING ; Deheng CAI ; Yi CAI
Journal of Acupuncture and Tuina Science 2008;6(5):309-311
Objective: To evaluate the effect of parallel scalp acupuncture therapy on hemodynamic function of cerebral circulation in post-stroke patients. Methods: Twenty post-stroke patients were taken as our objects. The cerebral circulation indices before and after parallel acupuncture therapy, were detected with KF-3000 Brain Circulation Analyze, to compare the change of hemodynamics indexes before and after parallel scalp acupuncture. Results: After the therapy, minimum and mean blood velocity of carotid artery (Vmin and Vmean) increased significantly (P<0.001); peripheral resistance (Rc) decreased significantly (P<0.001). And the other indices had no significant differences. Conclusion: Parallel Scalp Acupuncture can improve the state of cerebrovascular autoregulation, raise the velocity of blood, decrease the peripheral resistance, and increase the steady energy, total energy and the ratio of kinetic energy to total energy, decrease the ratio of oscillatory kinetic energy to total kinetic energy.
6.Alteration of the plasma concentration of all-trans retinoic acid(ATRA) in type 1 diabetes mellitus
Li DING ; Dehong CAI ; Di WANG
Chinese Journal of Diabetes 2006;14(1):50-51
To study the abnormality of the plasma concentration of ATRA in T1DM patients.T1DM patients(n=26),T2DM patients(n=33) and healthy people(n=30) were enrolled.The plasma concentration of ATRA was determined by HPLC.Compared with T2DM patients and healthy people,the concentration of ATRA increased significantly in T1DM patients.
7.The anatomic relationship between the thoracic transverse process and adjacent bony structures
Xingang CUI ; Zihai DING ; Jinfang CAI
Chinese Journal of Orthopaedic Trauma 2014;16(6):518-520
Objective To study the anatomic relationship between the thoracic transverse process and adjacent bony structures and its clinical significance for thoracic screw fixation.Methods The present anatomic measurement used 45 dry cadaveric specimens of the normal adult thoracic vertebrae.We measured the distances from the horizontal midline of the transverse process to the superior,middle and inferior margius of the pedicle,the height of the anterolateral transverse process sheltered by ribs,and the position at the horizontal midline of the transverse process corresponding to the vertebral body.Results The horizontal midlines margius of the transverse processes of T1 to T10 are localized in the plane ranging from the superior to the inferior margins of the pedicle.The midlines of the transverse process are closer at T6 and T7 while more apart at T9 and T10.From T1 to T8,the anterolateral transverse process is totally or mostly sheltered by ribs,but the shelter is much less at T9 and T10.The horizontal midline of the transverse process corresponds to the upper 1/3 or middle 1/3 of the vertebral body.Conclusion Thoracic screw fixation across the transverse process to the vertebral body is safe,reliable and feasible in clinic.
8.Thoughts on management of scientific research instruments in the Second Military Medical University
Li DING ; Guojun CAI ; Yuanying JIANG
Chinese Journal of Medical Science Research Management 2010;23(5):320-321
As the investments from the state and society in universities increased rapidly, the scientific and technological resources gained huge promotion. However, the efficiency of some instruments remained low, and the repeated purchases of some instruments occurred frequently. Here the authors discussed about building a practical, reasonable and efficient system for lab management.
9.The association of platelet-derived endothelial cell growth factor with bladder transitional cell carcinoma
Yichun ZHENG ; Wei DING ; Songliang CAI
Chinese Journal of Urology 2001;0(11):-
Objective To investigate the correlation of clinical and pathological characteristics of bladder transitional cell carcinoma(BTCC) with platelet-derived endothelial cell growth factor (PD-ECGF). Methods Expression of PD-ECGF,VEGF and MVD were examined in the specimens of 52 cases of BTCC by Envision immunohistochemical staining.All the 52 cases were followed up via interview for a period of 5 years. Results Of the 52 cases 50 provided complete relevant data.The 5-year postoperative tumor-free survival rate was 42.9%(21/49) and overall survival rate was 78.0%(39/50).The positive expression rate of PD-ECGF in G 1 tumors was 17.6%(3/17);in G 2,59.3%(16/27) and in G 3,87.5%(7/8)(P
10.The study of the induction of thymocytes apoptotisis by superantigen SEB in vitro
Li DING ; Dehong CAI ; Dingwen JIANG
Chinese Journal of Immunology 1985;0(02):-
Objective:To investigate whether superantigen SEB,with the assistance of APCs,could induce apoptosis of thymocytes in vitro,and to study the mechanism involved.Methods:SEB was given to thymocytes which were cultured together with APCs.Apoptosis was detected by DNA electrophoresis and DNA fragmentation assay.Expressions of Fas and FasL were detected by flow cytometry.Results:The thymocytes treated with SEB had the characters of apoptosis,and the apoptotic rate and expressions of Fas and FasL was significantly increased compared with control.Conclusion:SEB,together with APCs,can induce apoptosis of thymocytes in vitro,high expressions of Fas and FasL on thymocyte may participate in the mediation of apoptosis.This may provide a method to study the negative selection of thymocytes.