Objective:To investigate the effect of moderatehy pothermia on tumor necrosis factor alpha(TNF-?),interleukin-6(IL-6) and intedeukin-8(IL-8)in cerebrospinal fluid(CSF)of patients with severe traumatic brain injury(STBI)and its clinical significance.Methods:Forty patients with severe traumatic brain injury were randomly divided into hypothermic group and control group.Inclusion criteria included Glasgow Coma Scale(GCS)score ≤8 and time of after injury to on admission must be within 6 hours.TNF-?,IL-6,IL-8concentrations of CSF were tested before and after hypothermic therapy by radioimmunoassay.Results:Levels of serum TNF-?,IL-6 and IL-8 were decreased more significantly in the moderate hypothermia group than the control group(P

Objective To investigate the standard hemicraniectomy and temporal muscleresection therapeutic in the treatment effect of massive cerebral infarction patients .Methods Looking back at my hospital from February 2006 to October 2012 massive cerebral infarction patients ,30 cases were divided into two groups ,namely simple drug treatment(group A) ,the standard hemicrani-ectomy combined temporal muscleresection treatment (group B) .Followed up two groups of patients and deaths neurological deficit situation after treatment ,compared two groups of patients in hospital mortality and one month after treatment ,neurological impair-ment score .Results After treatment ,the patient midline reply ,mortality ,cure rates three aspects ,group B than the group A .Con-clusion Standard hemicraniectomy combined temporal muscle resection in the treatment can reduce the mortality rate of patients w ith active .

Objective: To summarize the effective of high intensity interval training on cognitive executive function among adolescents through Meta analysis,and to provide reference for medical rehabilitation and physical education practice. Methods: Literature search was conducted for Chinese and English keywords "High Intensity Interval Training", "Cognition", "Cognition Function"，"Executive Function" and "Executive Controls" regarding the effect of high intensity interval training on cognitive executive function among adolescents published prior to September 20, 2020 in PubMed, Cochrane library, Web of science, Embase, the China National Knowledge Infrastructure (CNKI), the Wanfang database and the VIP database. Stata 14 software and Revman 5.3 software were used for Meta analysis, fixed effect or random effect model was used to combine the results based on the heterogeneity. Results: The response time of Stroop test immediately after acute high intensity interval training significantly decreased ( SMD=0.70，95%CI =0.28-1.11， z=3.29，P <0.01); there was no significant change in response time of Stroop test 30 min after training ( SMD=0.23，95%CI=-0.14-0.60，z=1.23，P >0.05); the correct rate of Stroop test immediately after acute high intensity interval training increased significantly ( SMD=0.26，95%CI=0.03-0.50，z=2.21，P <0.05); there was no significant change in correct rate of Stroop test 30 min after training ( SMD=-1.38，95%CI=-4.28-1.52，z=0.93，P >0.05). After long term high intensity interval training, the response time of Stroop and TMT test were significantly shortened ( SMD=0.38, 95%CI=0.07-0.70, z=2.41, P < 0.05 ). Conclusion Acute and long term high intensity interval training can effectively improve cognitive executive function among adolescents, but the long term effect of acute training is unclear.