1.Strengthening the Management of Medical Measurement and Ensuring the Safe Use of Medical Equipment
Chinese Medical Equipment Journal 1993;0(06):-
Strengthening the management of medical measurement is introduced to ensure the safe use of medical equipment. The methods about strengthening the management of medical measurement is introduced from the three aspects in which strengthening the construct of measurement institution and rational allocation of staff, regulating the process to ensure the verification quality, multi-path detection and equipment to ensure that more controlled, at the same time, in maintaining the accuracy and security of instruments and equipment has done a number of exploration.
2.Design of digital video acquisition card based on TMS320C6201
Na WEI ; Zheng WANG ; Liang CUI ; Dianzhong HUANG ; Yue TIAN
Chinese Medical Equipment Journal 2004;0(07):-
Conventional digital video acquisition card can only collect but not process video frequency.This paper introduces the design of a digital video acquisition card based on C6000 DSP chip of TI company,which can process digital video automatically and communicate with mainframe through PCI interface.
3.Research on management of medical equipment
Zheng WANG ; Dianzhong HUANG ; Na WEI ; Yanping SU
Chinese Medical Equipment Journal 2003;0(12):-
As a part of modern medical practice,medical treatment facility(MTF) has playing an important role in disease diagnosis and medical treatment;therefore,nowadays more attention is paid to the medical equipment management.The methods of equipment management which combine actuality and practical experience are introduced in order to make the management of medical equipment more scientific and effective.
4.Influences and Strategy of Temperature and Humidity to Medical Equipments
Yanping SU ; Xiangdong LI ; Zheng WANG ; Dianzhong HUANG
Chinese Medical Equipment Journal 2003;0(10):-
To analyze and study the influences of temperature and humidity to the medical equipments, and indicate the problem and strategy of the medical equipment in the operation. To give some references in installation and maintenance of facilities.
5.Medical Image Segmentation Method Based on Texture Character and GRBF Network
Na WEI ; Xiangdong LI ; Dianzhong HUANG ; Zheng WANG
Chinese Medical Equipment Journal 2003;0(11):-
Objective To get a better medical image segmentation result by studing a new image segmentation method. Methods Medical images were segmented using image segmentation method based on texture character and generalized radial basis function neural networks. The texture character parameters were obtained according to gray level co-occurrence matrix. The parameters were input to the generalized radial basis function neural networks to train the network. Results Comparatively, perfect binary images were obtained by using this new image segmentation method. Conclusion The emulational results show that the method is an effective medical image segmentation method.
6.The identification value of diffusion weighted imaging in different molecular subtypes for breast cancer classification
Guanqiao JIN ; Danke SU ; Dianzhong LUO ; Shaolü LAI ; Ningbin LUO ; Wei KAN ; Xiangyang HUANG ; Xianliu FANG
Journal of Practical Radiology 2015;(6):929-932,941
Objective To investigate the value of diffusion weighted imaging (DWI)in identification of different molecular sub-types for breast cancer classifications.Methods All patients with breast cancer were divided into four subtypes groups by immuno-histochemistry results including Luminal A subtype,Luminal B subtype,HER2-over expressing (HER2-OE)subtype,and triple negative breast cancer (TNBC),respectively.The means of maximum,average,and minimum ADC of the lesions in all patients were recorded.The analysis of ANOVA and least significant difference test (LSD-t )were used for the statistical evaluation.Results There were significant differences in maximum ADC,average ADC,and minimum ADC among Luminal A subtype (n=21),Lu-minal B subtype (n=22),HER2-OE subtype (n=1 7)and TNBC subtype (n=12)groups (P =0.025,0.039 and 0.041,respec-tively).However,paired comparison in mean of maximum ADC,average ADC and minimum ADC by LSD-t multiple comparisons among Luminal A,Luminal B,HER2-OE and TNBC respectively were not significantly different.Conclusion DWI may be difficult to discriminate the molecular subtypes of breast cancer classification before surgery or biopsy.
7.Value of apparent diffusion coefficient histogram analysis in the assessment of response to neoadjuvant chemotherapy in patients with in locally advanced breast cancer
Guanqiao JIN ; Danke SU ; Dianzhong LUO ; Shaolyu LAI ; Ningbin LUO ; Wei KANG ; Xiangyang HUANG ; Xianliu FANG
Chinese Journal of Radiology 2015;(7):491-494
Objective To investigate the value of ADC histogram analysis in the assessment of response to neoadjuvant chemotherapy (NACT) in patients with in locally advanced breast cancer (LABC). Methods Thirty?five female patients with invasive ductal carcinoma proved by pathology before NACT and treated with operation after NACT were retrospectively analyzed. All patients were received MR examination (including non?enhanced MRI, enhanced?MRI, and DWI) breast before NACT. After neoadjuvant chemotherapy, 19 of 35 patients were categorized as responders and 16 were categorized as non?responders according response evaluation criteria in solid tumors criteria. Per?patient weighted ADC histograms were generated. Mean ADC, mode ADC, maximum ADC, minimum ADC, median ADC, skewness, and kurtosis were analyzed by using t test between responders and non responders groups. ROC curves were constructed to determine the optimum threshold for each histogram parameter to differentiate non?responders and responders in breast cancers. The optimal threshold values, determined by maximal Youden index were selected when significant differences existed in two groups. Results Mean, minimum, skewness, and kurtosis of ADC between responders and non?responders group were(0.955 ± 0.135)× 10?3mm2/s,(0.535 ± 0.115)×10?3mm2/s,0.85±0.61, 2.93±0.17,and(1.103±0.233)×10?3 mm2/s,(0.650±0.104)×10?3mm2/s,-0.42± 0.17, 3.11 ± 0.25,respectively. Significant differences were found mean ADC, minimum ADC, skewness, and kurtosis (t=2.345, 3.096, 8.051 and 2.524,P<0.05), and there was no differences in mode, median, maximum between responders and non?responders(P>0.05).We set the optimal threshold criteria of mean ADC (0.956×10?3mm2/s), minimum ADC (0.580×10?3mm2/s), skewness (0.890), sensitivity, specificity of three parameters for predicting responders in LABC were 73.7%,62.5%, 78.9%,68.8%, and 63.2%,75.0%, respectively, and the areas under ROC curve of mean ADC, minimum ADC, skewness was 0.678, 0.770, and 0.890, respectively. Kurtosis of responders and non?responders did not get cutoff value for much more overlap. Conclusion ADC histogram analysis is valuable in predicting LABC in patients with NACT effect, the minimum and skewness of ADC is highest sensitivity, specificity, respectively.
8.Prevalence of Avian Influenza Virus Receptor in Human Respiratory Tract
Zengfeng ZHANG ; Xiaohui FAN ; Kangsheng LI ; Kai HUANG ; Dianzhong LUO ; Zhenbo FENG ; Minyi WEI ; Yi GUAN ; Honglin CHEN ; Jinxia ZHANG
Progress in Biochemistry and Biophysics 2008;35(12):1387-1393
SAαt2,6 and SAα2,3 linked sialic acid molecules on epithelial cell membrane served as receptors for influenza virus, which axe specifically recognized by human and avian influenza viruses, respectively. The distribution of these two species of sialic acids in human respiratory tract from different anatomical sites and different age groups was investigated. The results showed that SAα2,3Gal species was prevalent in respiratory bronchiole and lung alveolar epithelium, but was infiequent in trachea, bronchus and bronchiole. On the contrary, the SAα2,6Gal species was more common in the trachea and bronchus and to a lesser degree in the alveolar epithelium. When compared the expression levels of SAα2,6Gal and α2,3Gal in the respiratory tract among different age groups, no significant difference was found. In the ex vivo H5N1 virus infection study, alveolus epithelium were found to be more susceptible to avian influenza than trachea and bronchus epithelial cells. These results suggest that the human respiratory tract, to some extent, is permissive for avian influenza viruses. The currently-observed limited human to human transmission of H5N1 virus may be associated with the different abundance of SAα2,3Gal linkages in human upper respiratory tract among individuals.